Research output per year
Research output per year
Research output
- 43 results
Search results
-
2023
Antigen presentation by B cells enables epitope spreading across an MHC barrier
Fahlquist-Hagert, C., Wittenborn, T. R., Terczyńska-Dyla, E., Kastberg, K. S., Yang, E., Rallistan, A. N., Markett, Q. R., Winther, G., Fonager, S., Voss, L. F., Pedersen, M. K., van Campen, N., Ferapontov, A., Jensen, L., Huang, J., Nieland, J. D., van der Poel, C. E., Palmfeldt, J., Carroll, M. C., Utz, P. J., & 3 others, 31 Oct 2023, In: Nature Communications. 14, 1, 6941.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile1 Citation (Scopus)21 Downloads (Pure) -
Histological and MRI brain atlas of the common shrew, Sorex araneus, with brain region-specific gene expression profiles
Baldoni, C., Thomas, W. R., von Elverfeldt, D., Reisert, M., Làzaro, J., Muturi, M., Dávalos, L. M., Nieland, J. D. & Dechmann, D. K. N., 3 May 2023, In: Frontiers in Neuroanatomy. 17, 1168523.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile20 Downloads (Pure) -
Inhibition of carnitine palmitoyl-transferase 1 is a potential target in a mouse model of Parkinson's disease
Trabjerg, M. S., Andersen, D. C., Huntjens, P., Mørk, K., Warming, N., Kullab, U. B., Skjønnemand, M-L. N., Oklinski, M. K., Oklinski, K. E., Bolther, L., Kroese, L. J., Pritchard, C. E. J., Huijbers, I. J., Corthals, A., Søndergaard, M. T., Kjeldal, H. B., Pedersen, C. F. M. & Nieland, J. D. V., 21 Jan 2023, In: NPJ Parkinson's disease. 9, 1, 6.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile4 Citations (Scopus)60 Downloads (Pure) -
Rethinking neurodegenerative diseases: neurometabolic concept linking lipid oxidation to diseases in the central nervous system
Helgudottir, S. S., Nieland, J. D. & Mørkholt, A. S., 8 Nov 2023, In: Neural Regeneration Research.Research output: Contribution to journal › Journal article › Research › peer-review
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2022
Neuroprotective Effect of Sonic Hedgehog Mediated PI3K/AKT Pathway in Amyotrophic Lateral Sclerosis Model Mice
Qi, Y., Yang, C., Zhao, H., Deng, Z., Xu, J., Liang, W., Sun, Z. & Nieland, J. D. V., Nov 2022, In: Molecular Neurobiology. 59, 11, p. 6971-6982 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile3 Citations (Scopus)35 Downloads (Pure) -
2021
Downregulating carnitine palmitoyl transferase 1 affects disease progression in the SOD1 G93A mouse model of ALS
Trabjerg, M. S., Andersen, D. C., Huntjens, P., Oklinski, K. E., Bolther, L., Hald, J. L., Baisgaard, A. E., Mørk, K., Warming, N., Kullab, U. B., Kroese, L. J., Pritchard, C. E. J., Huijbers, I. J. & Nieland, J. D. V., 30 Apr 2021, In: Communications Biology. 4, 1, 509.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile16 Citations (Scopus)128 Downloads (Pure) -
Maternal Separation Followed by Chronic Mild Stress in Adulthood Is Associated with Concerted Epigenetic Regulation of AP-1 Complex Genes
Lundgaard Donovan, L., Henningsen, K., Flou Kristensen, A., Wiborg, O., Nieland, J. D. & Lichota, J., 16 Mar 2021, In: Journal of Personalized Medicine. 11, 3, 209.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile6 Citations (Scopus)57 Downloads (Pure) -
Mitochondria–A target for attenuation of astrocyte pathology
Morch, M. T., Khorooshi, R., Marczynska, J., Dubik, M., Nielsen, S., Nieland, J. D., Asgari, N. & Owens, T., 15 Sept 2021, In: Journal of Neuroimmunology. 358, 577657.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile1 Citation (Scopus)46 Downloads (Pure) -
2020
Dysregulation of metabolic pathways by carnitine palmitoyl-transferase 1 plays a key role in central nervous system disorders: experimental evidence based on animal models
Trabjerg, M. S., Mørkholt, A. S., Lichota, J., Oklinski, M. K. E., Andersen, D. C., Jønsson, K., Mørk, K., Skjønnemand, M-L. N., Kroese, L. J., Pritchard, C. E. J., Huijbers, I. J., Gazerani, P., Corthals, A. & Nieland, J. D. V., 24 Sept 2020, In: Scientific Reports. 10, 1, 15583.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile12 Citations (Scopus)123 Downloads (Pure) -
Pharmacological inhibition of carnitine palmitoyl transferase 1 inhibits and reverses experimental autoimmune encephalitis in rodents
Mørkholt, A. S., Oklinski, M. K., Larsen, A., Bockermann, R., Issazadeh-Navikas, S., Nieland, J. G. K., Kwon, T-H., Corthals, A., Nielsen, S. & Nieland, J. D. V., 2020, In: PLOS ONE. 15, 6, 17 p., e0234493.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile17 Citations (Scopus)131 Downloads (Pure) -
2019
CPT1A plays a key role in the development and treatment of multiple sclerosis and experimental autoimmune encephalomyelitis
Mørkholt, A. S., Trabjerg, M. S., Oklinski, M. K. E., Bolther, L., Kroese, L. J., Pritchard, C. E. J., Huijbers, I. J. & Nieland, J. D. V., 16 Sept 2019, In: Scientific Reports. 9, 1, 13299.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile15 Citations (Scopus)142 Downloads (Pure) -
Identification and characterization of potent and selective aquaporin-3 and aquaporin-7 inhibitors
Sonntag, Y., Gena, P., Maggio, A., Singh, T., Artner, I., Oklinski, M. K., Johanson, U., Kjellbom, P., Nieland, J. D., Nielsen, S., Calamita, G. & Rützler, M., 3 May 2019, In: The Journal of Biological Chemistry. 294, 18, p. 7377-7387 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access36 Citations (Scopus) -
2018
Identification of brain antigens recognized by autoantibodies in experimental autoimmune encephalomyelitis-induced animals treated with etomoxir or interferon-β
Mørkholt, A. S., Kastaniegaard, K., Trabjerg, M. S., Gopalasingam, G., Niganze, W., Larsen, A., Stensballe, A., Nielsen, S. & Nieland, J. D., 4 May 2018, In: Scientific Reports. 8, 1, 11 p., 7092.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile10 Citations (Scopus)344 Downloads (Pure) -
2017
Blocking of carnitine palmitoyl transferase 1 potently reduces stress-induced depression in rat highlighting a pivotal role of lipid metabolism
Mørkholt, A. S., Wiborg, O., Nieland, J. G. K., Nielsen, S. & Nieland, J. D., 19 May 2017, In: Scientific Reports. 7, 9 p., 2158.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile20 Citations (Scopus)372 Downloads (Pure) -
2013
Mutant HSP70 reverses autoimmune depigmentation in vitiligo
Mosenson, J. A., Zloza, A., Nieland, J. D., Garrett-Mayer, E., Eby, J. M., Huelsmann, E. J., Kumar, P., Denman, C. J., Lacek, A. T., Kohlhapp, F. J., Alamiri, A., Hughes, T., Bines, S. D., Kaufman, H. L., Overbeck, A., Mehrotra, S., Hernandez, C., Nishimura, M. I., Guevara-Patino, J. A. & Le Poole, I. C., 27 Feb 2013, In: Science Translational Medicine. 5, 174, 174ra28.Research output: Contribution to journal › Journal article › Research › peer-review
101 Citations (Scopus) -
2009
Cationic liposomes target sites of acute neuroinflammation in experimental autoimmune encephalomyelitis
Cavaletti, G., Cassetti, A., Canta, A., Galbiati, S., Gilardini, A., Oggioni, N., Rodriguez-Menendez, V., Fasano, A., Liuzzi, G. M., Fattler, U., Ries, S., Nieland, J., Riccio, P. & Haas, H., 5 Oct 2009, In: Molecular Pharmaceutics. 6, 5, p. 1363-1370 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
28 Citations (Scopus) -
2008
Trimerization of apolipoprotein A-I retards plasma clearance and preserves antiatherosclerotic properties
Graversen, J. H., Laurberg, J. M., Andersen, M. H., Falk, E., Nieland, J., Christensen, J., Etzerodt, M., Thøgersen, H. C. & Moestrup, S. K., Feb 2008, In: Journal of Cardiovascular Pharmacology. 51, 2, p. 170-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
21 Citations (Scopus) -
2007
Vaccination trial with HPV16 L1E7 chimeric virus-like particles in women suffering from high grade cervical intraepithelial neoplasia (CIN 2/3)
Kaufmann, A. M., Nieland, J. D., Jochmus, I., Baur, S., Friese, K., Gabelsberger, J., Gieseking, F., Gissmann, L., Glasschröder, B., Grubert, T., Hillemanns, P., Höpfl, R., Ikenberg, H., Schwarz, J., Karrasch, M., Knoll, A., Küppers, V., Lechmann, M., Lelle, R. J., Meissner, H., & 6 others, 15 Nov 2007, In: International Journal of Cancer. 121, 12, p. 2794-2800 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
122 Citations (Scopus) -
2005
A new therapeutic approach to treat psoriasis by inhibition of fatty acid oxidation by Etomoxir
Caspary, F., Elliott, G., Navé, B. T., Verzaal, P., Rohrbach, M., Das, P. K., Nagelkerken, L. & Nieland, J. D., 1 Nov 2005, In: British Journal of Dermatology. 153, 5, p. 937-944 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
25 Citations (Scopus) -
Multiplex human papillomavirus serology based on in situ-purified glutathione S-transferase fusion proteins
Waterboer, T., Sehr, P., Michael, K. M., Franceschi, S., Nieland, J. D., Joos, T. O., Templin, M. F. & Pawlita, M., 1 Oct 2005, In: Clinical Chemistry. 51, 10, p. 1845-1853 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access472 Citations (Scopus) -
2003
Identification of a naturally processed HLA-A*0201 HPV18 E7 T cell epitope by tumor cell mediated in vitro vaccination
Kather, A., Ferrara, A., Nonn, M., Schinz, M., Nieland, J., Schneider, A., Dürst, M. & Kaufmann, A. M., 10 Apr 2003, In: International Journal of Cancer. 104, 3, p. 345-353 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
25 Citations (Scopus) -
2001
HPV16 L1E7 chimeric virus-like particles induce specific HLA-restricted T cells in humans after in vitro vaccination
Kaufmann, A. M., Nieland, J., Schinz, M., Nonn, M., Gabelsberger, J., Meissner, H., Mller, R. T., Jochmus, I., Gissmann, L., Schneider, A. & Drst, M., 15 Apr 2001, In: International Journal of Cancer. 92, 2, p. 285-293 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
72 Citations (Scopus) -
Physical interaction of human papillomavirus virus-like particles with immune cells
Da Silva, D. M., Velders, M. P., Nieland, J. D., Schiller, J. T., Nickoloff, B. J. & Kast, W. M., 1 Jan 2001, In: International Immunology. 13, 5, p. 633-641 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access51 Citations (Scopus) -
1999
Chimeric papillomavirus virus-like particles induce a murine self- antigen-specific protective and therapeutic antitumor immune response
Nieland, J. D., Da Silva, D. M., Velders, M. P., De Visser, K. E., Schiller, J. T., Müller, M. & Kast, W. M., 1 May 1999, In: Journal of Cellular Biochemistry. 73, 2, p. 145-152 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
46 Citations (Scopus) -
Induction of HPV16 capsid protein-specific human T cell responses by virus-like particles
Rudolf, M. P., Nieland, J. D., DaSilva, D. M., Velders, M. P., Müller, M., Greenstone, H. L., Schiller, J. T. & Kast, W. M., Mar 1999, In: Biological Chemistry. 380, 3, p. 335-340 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
46 Citations (Scopus) -
1998
CD40 and CD70 co-stimulate a potent in vivo antitumor T cell response
Nieland, J. D., Graus, Y. F., Dortmans, Y. E., Kremers, B. L. J. M. & Kruisbeek, A. M., 1 Jan 1998, In: Journal of Immunotherapy. 21, 3, 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
45 Citations (Scopus) -
Chimeric papillomavirus virus-like particles elicit antitumor immunity against the e7 oncoprotein in an hpv16 tumor model
Greenstone, H. L., Nieland, J. D., De Visser, K. E., De Bruijn, M. L. H., Kirnbauer, R., Roden, R. B. S., Lowy, D. R., Kast, W. M. & Schiller, J. T., 17 Feb 1998, In: Proceedings of the National Academy of Sciences of the United States of America. 95, 4, p. 1800-1805 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access312 Citations (Scopus) -
Functional analysis of Ran/TC4 as a protein regulating T-cell costimulation
Nieland, J. D., Haks, M. C., Kremers, B. L. J. M., Leupers, T. J. M., Bakker, A. Q., Offringa, R. & Kruisbeek, A. M., 1 Dec 1998, In: Cancer Gene Therapy. 5, 5, p. 259-273 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
7 Citations (Scopus) -
PBLs of early breast carcinoma patients with a high nuclear grade tumor unlike PBLs of cervical carcinoma patients do not show a decreased TCRζ expression but are functionally impaired
Nieland, J. D., Loviscek, K., Kono, K., Albain, K. S., McCall, A. R., Potkul, R. K., Fisher, S. G., Velders, M. P., Petersson, M., Kiessling, R. & Martin Kast, W., 1 Jan 1998, In: Journal of Immunotherapy. 21, 4, 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
23 Citations (Scopus) -
1997
Identification of peptides for immunotherapy of cancer. It is still worth the effort
Velders, M. P., Nieland, J. D., Rudolf, M. P., Loviscek, K., Weijzen, S., De Visser, K. E., Fatima Macedo, M., Carbone, M. & Kast, W. M., 1 Jan 1997, In: Critical Reviews in Immunology. 18, 1-2, p. 7-27 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
21 Citations (Scopus) -
1995
A T cell lymphoma can provide potent co-stimulatory effects to T cells that are not mediated by B7-1, B7-2, CD40, HSA or CD70
Nieland, J. D. & Kruisbeek, A. M., 1 Nov 1995, In: International Immunology. 7, 11, p. 1827-1838 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
8 Citations (Scopus) -
Novel mAbs reveal potent co-stimulatory activity of murine CD27
Gravestein, L. A., Nieland, J. D., Kruisbeek, A. M. & Borst, J., 1 Apr 1995, In: International Immunology. 7, 4, p. 551-557 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
82 Citations (Scopus) -
1994
Flow cytometric analysis reveals unexpected shared antigens between histologically defined populations of thymic stromal cells
Izon, D. J., Nieland, J. D., Godfrey, D. I., Boyd, R. L. & Krulsbeek, A. M., 1 Jan 1994, In: International Immunology. 6, 1, p. 31-39 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
19 Citations (Scopus) -
Identification of an H-2 Kb-presented Moloney murine leukemia virus cytotoxic T-lymphocyte epitope that displays enhanced recognition in H-2 Db mutant bm13 mice
Sijts, A. J. A. M., De Bruijn, M. L. H., Ressing, M. E., Nieland, J. D., Mengedé, E. A. M., Boog, C. J. P., Ossendorp, F., Kast, W. M. & Melief, C. J. M., 1 Sept 1994, In: Journal of Virology. 68, 9, p. 6038-6046 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
30 Citations (Scopus) -
1993
Cd28 - B7 interactions are not required for intrathymic clonal deletion
Jones, L. A., Izon, D. J., Nieland, J. D., Linsley, P. S. & Kruisbeek, A. M., May 1993, In: International Immunology. 5, 5, p. 503-512 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
70 Citations (Scopus) -
1992
Cytotoxic T lymphocytes against the antigen‐processing‐defective RMA‐S tumor cell line
Sijts, A. J. A. M., De Bruijn, M. L. H., Nieland, J. D., Kast, W. M. & Melief, C. J. M., Jun 1992, In: European Journal of Immunology. 22, 6, p. 1639-1642 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
30 Citations (Scopus) -
Mechanism of tolerance induction
Kruisbeek, A. M., Nieland, J. D. & Jones, L. A., 1 Dec 1992, In: Advances in Experimental Medicine and Biology. 323, p. 101-110 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
1 Citation (Scopus) -
Mechanisms of induction of primary virus‐specific cytotoxic T lymphocyte responses
De Bruijn, M. L. H., Nieland, J. D., Schumacher, T. N. M., Ploegh, H. L., Martin Kast, W. & Melief, C. J. M., Nov 1992, In: European Journal of Immunology. 22, 11, p. 3013-3020 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
59 Citations (Scopus) -
Processing and presentation of intact hen egg‐white lysozyme by dendritic cells
De Bruijn, M. L. H., Nieland, J. D., Harding, C. V. & Melief, C. J. M., Sept 1992, In: European Journal of Immunology. 22, 9, p. 2347-2352 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
41 Citations (Scopus) -
1991
Peptide loading of empty major histocompatibility complex molecules on RMA‐S cells allows the induction of primary cytotoxic T lymphocyte responses
De Bruijn, M. L. H., Schumacher, T. N. M., Nieland, J. D., Ploegh, H. L., Martin Kast, W. & Melief, C. J. M., Dec 1991, In: European Journal of Immunology. 21, 12, p. 2963-2970 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
100 Citations (Scopus) -
1990
N-linked glycan modification on antigen-presenting cells restores an allospecific cytotoxic T cell response
Neefjes, J. J., De Bruijn, M. L. H., Boog, C. J. P., Nieland, J. D., Boes, J., Melief, C. J. M. & Ploegh, H. L., 1 Feb 1990, In: Journal of Experimental Medicine. 171, 2, p. 583-588 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access28 Citations (Scopus) -
1989
Distinct chromosomal abnormalities in murine leukemia virus‐induced T‐ and B‐cell lymphomas
Vasmel, W. L. E., Matthews, E. A., Gillis, C. P. M., Nieland, J., Borst, E. A., Leupers, C. J. M., Melief, C. J. M. & Slater, R. M., 15 Jun 1989, In: International Journal of Cancer. 43, 6, p. 1112-1119 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
6 Citations (Scopus) -
1986
Imbalanced MHC class II molecule expression at surface of murine B cell lymphomas
Zijlstra, M., Vasmel, W. L. E., Voormanns, M., De Goede, R. E. Y., Schoenmakers, H. J., Nieland, J., Slater, R. M. & Melief, C. J. M., 1 May 1986, In: Journal of Experimental Medicine. 163, 5, p. 1213-1226 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access6 Citations (Scopus)