• Fredrik Bajers Vej 7, E4 121

    9220 Aalborg Ø

    Denmark

1986 …2019
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Research Output 1986 2019

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Journal article
2019
7 Downloads (Pure)

CPT1A plays a key role in the development and treatment of multiple sclerosis and experimental autoimmune encephalomyelitis

Mørkholt, A. S., Trabjerg, M. S., Oklinski, M. K. E., Bolther, L., Kroese, L. J., Pritchard, C. E. J., Huijbers, I. J. & Nieland, J. D. V., 16 Sep 2019, In : Scientific Reports. 9, 1

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
2 Citations (Scopus)

Identification and characterization of potent and selective aquaporin-3 and aquaporin-7 inhibitors

Sonntag, Y., Gena, P., Maggio, A., Singh, T., Artner, I., Oklinski, M. K., Johanson, U., Kjellbom, P., Nieland, J. D., Nielsen, S., Calamita, G. & Rützler, M., 3 May 2019, In : The Journal of Biological Chemistry. 294, 18, p. 7377-7387 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Aquaporin 3
Aquaporins
Aquaglyceroporins
Permeability
Protein Isoforms
2018
2 Citations (Scopus)
208 Downloads (Pure)
Autoimmune Experimental Encephalomyelitis
Autoantibodies
Interferons
Multiple Sclerosis
Antigens
2 Citations (Scopus)
208 Downloads (Pure)

Identification of brain antigens recognized by autoantibodies in experimental autoimmune encephalomyelitis-induced animals treated with etomoxir or interferon-β

Mørkholt, A. S., Kastaniegaard, K., Trabjerg, M. S., Gopalasingam, G., Niganze, W., Larsen, A., Stensballe, A., Nielsen, S. & Nieland, J. D., 4 May 2018, In : Scientific Reports. 8, 1, 11 p., 7092.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Autoimmune Experimental Encephalomyelitis
Autoantibodies
Interferons
Multiple Sclerosis
Antigens
2017
3 Citations (Scopus)
242 Downloads (Pure)

Blocking of carnitine palmitoyl transferase 1 potently reduces stress-induced depression in rat highlighting a pivotal role of lipid metabolism

Mørkholt, A. S., Wiborg, O., Nieland, J. G. K., Nielsen, S. & Nieland, J. D., 19 May 2017, In : Scientific Reports. 7, 9 p., 2158.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Carnitine
Transferases
Lipid Metabolism
Depression
Citalopram
2013
48 Citations (Scopus)

Mutant HSP70 reverses autoimmune depigmentation in vitiligo

Mosenson, J. A., Zloza, A., Nieland, J. D., Garrett-Mayer, E., Eby, J. M., Huelsmann, E. J., Kumar, P., Denman, C. J., Lacek, A. T., Kohlhapp, F. J., Alamiri, A., Hughes, T., Bines, S. D., Kaufman, H. L., Overbeck, A., Mehrotra, S., Hernandez, C., Nishimura, M. I., Guevara-Patino, J. A. & Le Poole, I. C., 27 Feb 2013, In : Science Translational Medicine. 5, 174, 174ra28.

Research output: Contribution to journalJournal articleResearchpeer-review

Vitiligo
Melanocytes
Dendritic Cells
T-Lymphocytes
Phenotype
2009
17 Citations (Scopus)

Cationic liposomes target sites of acute neuroinflammation in experimental autoimmune encephalomyelitis

Cavaletti, G., Cassetti, A., Canta, A., Galbiati, S., Gilardini, A., Oggioni, N., Rodriguez-Menendez, V., Fasano, A., Liuzzi, G. M., Fattler, U., Ries, S., Nieland, J., Riccio, P. & Haas, H., 5 Oct 2009, In : Molecular Pharmaceutics. 6, 5, p. 1363-1370 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Autoimmune Experimental Encephalomyelitis
Liposomes
Blood-Brain Barrier
Blood Vessels
Spinal Cord
2007
100 Citations (Scopus)

Vaccination trial with HPV16 L1E7 chimeric virus-like particles in women suffering from high grade cervical intraepithelial neoplasia (CIN 2/3)

Kaufmann, A. M., Nieland, J. D., Jochmus, I., Baur, S., Friese, K., Gabelsberger, J., Gieseking, F., Gissmann, L., Glasschröder, B., Grubert, T., Hillemanns, P., Höpfl, R., Ikenberg, H., Schwarz, J., Karrasch, M., Knoll, A., Küppers, V., Lechmann, M., Lelle, R. J., Meissner, H. & 6 others, Müller, R. T., Pawlita, M., Petry, K. U., Pilch, H., Walek, E. & Schneider, A., 15 Nov 2007, In : International Journal of Cancer. 121, 12, p. 2794-2800 7 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Cervical Intraepithelial Neoplasia
Virion
Vaccination
Vaccines
Safety
2005
18 Citations (Scopus)

A new therapeutic approach to treat psoriasis by inhibition of fatty acid oxidation by Etomoxir

Caspary, F., Elliott, G., Navé, B. T., Verzaal, P., Rohrbach, M., Das, P. K., Nagelkerken, L. & Nieland, J. D., 1 Nov 2005, In : British Journal of Dermatology. 153, 5, p. 937-944 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Carnitine O-Palmitoyltransferase
Psoriasis
Fatty Acids
Skin
Therapeutics
326 Citations (Scopus)

Multiplex human papillomavirus serology based on in situ-purified glutathione S-transferase fusion proteins

Waterboer, T., Sehr, P., Michael, K. M., Franceschi, S., Nieland, J. D., Joos, T. O., Templin, M. F. & Pawlita, M., 1 Oct 2005, In : Clinical Chemistry. 51, 10, p. 1845-1853 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
Serology
Glutathione Transferase
Fusion reactions
Antibodies
Uterine Cervical Neoplasms
2003
23 Citations (Scopus)

Identification of a naturally processed HLA-A*0201 HPV18 E7 T cell epitope by tumor cell mediated in vitro vaccination

Kather, A., Ferrara, A., Nonn, M., Schinz, M., Nieland, J., Schneider, A., Dürst, M. & Kaufmann, A. M., 10 Apr 2003, In : International Journal of Cancer. 104, 3, p. 345-353 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

T-Lymphocyte Epitopes
Vaccination
Epitopes
Peptides
Neoplasms
2001
67 Citations (Scopus)

HPV16 L1E7 chimeric virus-like particles induce specific HLA-restricted T cells in humans after in vitro vaccination

Kaufmann, A. M., Nieland, J., Schinz, M., Nonn, M., Gabelsberger, J., Meissner, H., Mller, R. T., Jochmus, I., Gissmann, L., Schneider, A. & Drst, M., 15 Apr 2001, In : International Journal of Cancer. 92, 2, p. 285-293 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

HLA Antigens
Virion
Vaccination
T-Lymphocytes
Uterine Cervical Neoplasms
47 Citations (Scopus)

Physical interaction of human papillomavirus virus-like particles with immune cells

Da Silva, D. M., Velders, M. P., Nieland, J. D., Schiller, J. T., Nickoloff, B. J. & Kast, W. M., 1 Jan 2001, In : International Immunology. 13, 5, p. 633-641 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
Papillomaviridae
Virion
Antigen-Presenting Cells
B-Lymphocytes
Foreskin
1999
45 Citations (Scopus)

Chimeric papillomavirus virus-like particles induce a murine self- antigen-specific protective and therapeutic antitumor immune response

Nieland, J. D., Da Silva, D. M., Velders, M. P., De Visser, K. E., Schiller, J. T., Müller, M. & Kast, W. M., 1 May 1999, In : Journal of Cellular Biochemistry. 73, 2, p. 145-152 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Autoantigens
Virion
Neoplasm Antigens
Peptides
Immunization
44 Citations (Scopus)

Induction of HPV16 capsid protein-specific human T cell responses by virus-like particles

Rudolf, M. P., Nieland, J. D., DaSilva, D. M., Velders, M. P., Müller, M., Greenstone, H. L., Schiller, J. T. & Kast, W. M., Mar 1999, In : Biological Chemistry. 380, 3, p. 335-340 6 p.

Research output: Contribution to journalJournal articleResearchpeer-review

T-cells
Capsid Proteins
Viruses
Virion
T-Lymphocytes
1998
44 Citations (Scopus)

CD40 and CD70 co-stimulate a potent in vivo antitumor T cell response

Nieland, J. D., Graus, Y. F., Dortmans, Y. E., Kremers, B. L. J. M. & Kruisbeek, A. M., 1 Jan 1998, In : Journal of Immunotherapy. 21, 3, 1 p.

Research output: Contribution to journalJournal articleResearchpeer-review

T-Lymphocytes
Neoplasms
Aptitude
Cytotoxic T-Lymphocytes
Major Histocompatibility Complex
288 Citations (Scopus)

Chimeric papillomavirus virus-like particles elicit antitumor immunity against the e7 oncoprotein in an hpv16 tumor model

Greenstone, H. L., Nieland, J. D., De Visser, K. E., De Bruijn, M. L. H., Kirnbauer, R., Roden, R. B. S., Lowy, D. R., Kast, W. M. & Schiller, J. T., 17 Feb 1998, In : Proceedings of the National Academy of Sciences of the United States of America. 95, 4, p. 1800-1805 6 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
Oncogene Proteins
Virion
Immunity
Capsid Proteins
Vaccines
6 Citations (Scopus)

Functional analysis of Ran/TC4 as a protein regulating T-cell costimulation

Nieland, J. D., Haks, M. C., Kremers, B. L. J. M., Leupers, T. J. M., Bakker, A. Q., Offringa, R. & Kruisbeek, A. M., 1 Dec 1998, In : Cancer Gene Therapy. 5, 5, p. 259-273 15 p.

Research output: Contribution to journalJournal articleResearchpeer-review

T-Lymphocytes
Neoplasms
Proteins
ran GTP-Binding Protein
COS Cells
23 Citations (Scopus)

PBLs of early breast carcinoma patients with a high nuclear grade tumor unlike PBLs of cervical carcinoma patients do not show a decreased TCRζ expression but are functionally impaired

Nieland, J. D., Loviscek, K., Kono, K., Albain, K. S., McCall, A. R., Potkul, R. K., Fisher, S. G., Velders, M. P., Petersson, M., Kiessling, R. & Martin Kast, W., 1 Jan 1998, In : Journal of Immunotherapy. 21, 4, 1 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Lymphocytes
Breast Neoplasms
Carcinoma
Neoplasms
Interferons
1997
21 Citations (Scopus)

Identification of peptides for immunotherapy of cancer. It is still worth the effort

Velders, M. P., Nieland, J. D., Rudolf, M. P., Loviscek, K., Weijzen, S., De Visser, K. E., Fatima Macedo, M., Carbone, M. & Kast, W. M., 1 Jan 1997, In : Critical Reviews in Immunology. 18, 1-2, p. 7-27 21 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Immunotherapy
Peptides
Neoplasms
Vaccination
T-Lymphocytes
1995
8 Citations (Scopus)

A T cell lymphoma can provide potent co-stimulatory effects to T cells that are not mediated by B7-1, B7-2, CD40, HSA or CD70

Nieland, J. D. & Kruisbeek, A. M., 1 Nov 1995, In : International Immunology. 7, 11, p. 1827-1838 12 p.

Research output: Contribution to journalJournal articleResearchpeer-review

T-Cell Lymphoma
T-Lymphocytes
Concanavalin A
Interleukin-2
Lymphoma
76 Citations (Scopus)

Novel mAbs reveal potent co-stimulatory activity of murine CD27

Gravestein, L. A., Nieland, J. D., Kruisbeek, A. M. & Borst, J., 1 Apr 1995, In : International Immunology. 7, 4, p. 551-557 7 p.

Research output: Contribution to journalJournal articleResearchpeer-review

T-Lymphocytes
Thymocytes
B-Lymphocytes
Tumor Necrosis Factor Receptors
Concanavalin A
1994
18 Citations (Scopus)

Flow cytometric analysis reveals unexpected shared antigens between histologically defined populations of thymic stromal cells

Izon, D. J., Nieland, J. D., Godfrey, D. I., Boyd, R. L. & Krulsbeek, A. M., 1 Jan 1994, In : International Immunology. 6, 1, p. 31-39 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Stromal Cells
Antigens
Population
T-Lymphocytes
Dendritic Cells
28 Citations (Scopus)

Identification of an H-2 Kb-presented Moloney murine leukemia virus cytotoxic T-lymphocyte epitope that displays enhanced recognition in H-2 Db mutant bm13 mice

Sijts, A. J. A. M., De Bruijn, M. L. H., Ressing, M. E., Nieland, J. D., Mengedé, E. A. M., Boog, C. J. P., Ossendorp, F., Kast, W. M. & Melief, C. J. M., 1 Sep 1994, In : Journal of Virology. 68, 9, p. 6038-6046 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Murine leukemia virus
Moloney murine leukemia virus
cytotoxic T-lymphocytes
T-Lymphocyte Epitopes
Cytotoxic T-Lymphocytes
1993
68 Citations (Scopus)

Cd28 - B7 interactions are not required for intrathymic clonal deletion

Jones, L. A., Izon, D. J., Nieland, J. D., Linsley, P. S. & Kruisbeek, A. M., May 1993, In : International Immunology. 5, 5, p. 503-512 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Clonal Deletion
B7 Antigens
T-Lymphocytes
Superantigens
T-Cell Antigen Receptor-CD3 Complex
1992
25 Citations (Scopus)

Cytotoxic T lymphocytes against the antigen‐processing‐defective RMA‐S tumor cell line

Sijts, A. J. A. M., De Bruijn, M. L. H., Nieland, J. D., Kast, W. M. & Melief, C. J. M., Jun 1992, In : European Journal of Immunology. 22, 6, p. 1639-1642 4 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Cytotoxic T-Lymphocytes
Tumor Cell Line
Peptides
Major Histocompatibility Complex
Rauscher Virus
1 Citation (Scopus)

Mechanism of tolerance induction

Kruisbeek, A. M., Nieland, J. D. & Jones, L. A., 1 Dec 1992, In : Advances in Experimental Medicine and Biology. 323, p. 101-110 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

56 Citations (Scopus)

Mechanisms of induction of primary virus‐specific cytotoxic T lymphocyte responses

De Bruijn, M. L. H., Nieland, J. D., Schumacher, T. N. M., Ploegh, H. L., Martin Kast, W. & Melief, C. J. M., Nov 1992, In : European Journal of Immunology. 22, 11, p. 3013-3020 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Cytotoxic T-Lymphocytes
Dendritic Cells
T-Lymphocytes
Peptides
Major Histocompatibility Complex
38 Citations (Scopus)

Processing and presentation of intact hen egg‐white lysozyme by dendritic cells

De Bruijn, M. L. H., Nieland, J. D., Harding, C. V. & Melief, C. J. M., Sep 1992, In : European Journal of Immunology. 22, 9, p. 2347-2352 6 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Muramidase
Dendritic Cells
Proteins
Antigen Presentation
Chloroquine
1991
92 Citations (Scopus)

Peptide loading of empty major histocompatibility complex molecules on RMA‐S cells allows the induction of primary cytotoxic T lymphocyte responses

De Bruijn, M. L. H., Schumacher, T. N. M., Nieland, J. D., Ploegh, H. L., Martin Kast, W. & Melief, C. J. M., Dec 1991, In : European Journal of Immunology. 21, 12, p. 2963-2970 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Cytotoxic T-Lymphocytes
Major Histocompatibility Complex
Peptides
Adenovirus E1A Proteins
Sendai virus
1990
23 Citations (Scopus)

N-linked glycan modification on antigen-presenting cells restores an allospecific cytotoxic T cell response

Neefjes, J. J., De Bruijn, M. L. H., Boog, C. J. P., Nieland, J. D., Boes, J., Melief, C. J. M. & Ploegh, H. L., 1 Feb 1990, In : Journal of Experimental Medicine. 171, 2, p. 583-588 6 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
1989
6 Citations (Scopus)

Distinct chromosomal abnormalities in murine leukemia virus‐induced T‐ and B‐cell lymphomas

Vasmel, W. L. E., Matthews, E. A., Gillis, C. P. M., Nieland, J., Borst, E. A., Leupers, C. J. M., Melief, C. J. M. & Slater, R. M., 15 Jun 1989, In : International Journal of Cancer. 43, 6, p. 1112-1119 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Chromosome Aberrations
Lymphoma
Leukemia
Neoplasms
Cytogenetics
1986
6 Citations (Scopus)

Imbalanced MHC class II molecule expression at surface of murine B cell lymphomas

Zijlstra, M., Vasmel, W. L. E., Voormanns, M., De Goede, R. E. Y., Schoenmakers, H. J., Nieland, J., Slater, R. M. & Melief, C. J. M., 1 May 1986, In : Journal of Experimental Medicine. 163, 5, p. 1213-1226 14 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access