Projects per year
Personal profile
Research profile
I am an assistant professor working with the labs of Per H Nielsen and Mads Albertsen. The focuses of my postdoc have been recovering high-quality metagenome-assembled genomes of wastewater and anaerobic digester bacteria and archaea, and investigating the metabolic potential and phylogeny of key functional groups. I am also involved in projects investigating biogeochemical cycles through the bacteria and archaea of Denmark. My interests centre on the relationship of bacteria and archaea to the natural environment, and ways microorganisms are affected by or can help mitigate human impact.
I did my PhD at the Australian Centre for Ecogenomics (ACE) under the supervision of Prof. Gene Tyson and Dr. Ben Woodcroft and was part of an international team exploring the microbes in thawing permafrost. I did my Honours degree at ACE under the supervision of Prof. Phil Hugenholtz.
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Collaborations from the last five years
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Microflora Danica: The Microbiome of Denmark
Albertsen, M. (PI), Nielsen, P. H. (PI), Jensen, T. B. N. (Project Participant), Sørensen, E. A. (Project Participant), Sereika, M. (Project Participant), Dottorini, G. (Project Participant), Petriglieri, F. (Project Participant), Jørgensen, V. R. (Project Participant), Kirkegaard, R. H. (Project Participant), Yang, Y. (Project Participant), Karst, S. M. (Project Participant), Giguere, A. T. (Project Participant), Knutsson, S. (Project Participant), Singleton, C. M. (Project Participant), Dueholm, M. K. D. (Project Participant), Mølvang Dall, S. (Project Participant), Kristensen, J. M. (Project Participant) & Delogu, F. (Project Participant)
01/01/2019 → 31/12/2025
Project: Research
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Illumination of microbial dark matter
Nielsen, P. H. (PI), Dueholm, M. K. D. (Project Participant), Nierychlo, M. (Project Participant), Albertsen, M. (Project Participant), Hove Hansen, S. (Other), Dottorini, G. (Project Participant), Singleton, C. M. (Project Participant), Kondrotaite, Z. (Project Participant), Petersen, J. F. (Project Participant), Petriglieri, F. (PI) & Peces Gomez, M. (Project Participant)
01/01/2017 → 31/12/2024
Project: Research
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REPARES: Research platform on antibiotic resistance spread through wastewater treatment plants
Nielsen, P. H., Hove Hansen, S., Nierychlo, M. & Singleton, C. M.
01/10/2019 → 30/06/2023
Project: Research
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Long-Read Metagenome-Assembled Genomes Improve Identification of Novel Complete Biosynthetic Gene Clusters in a Complex Microbial Activated Sludge Ecosystem
Sanchez Navarro, R., Nuhamunada, M., Mohite, O., Wasmund, K., Albertsen, M., Gram, L., Nielsen, P. H., Weber, T. & Singleton, C. M., 29 Nov 2022, In: mSystems. 7, 6, e00632-22.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile15 Citations (Scopus)42 Downloads (Pure) -
Connecting structure to function with the recovery of over 1000 high-quality metagenome-assembled genomes from activated sludge using long-read sequencing
Singleton, C. M., Petriglieri, F., Kristensen, J. M., Kirkegaard, R. H., Michaelsen, T. Y., Andersen, M. H., Kondrotaite, Z., Karst, S. M., Dueholm, M. S., Nielsen, P. H. & Albertsen, M., 31 Mar 2021, In: Nature Communications. 12, 1, 13 p., 2009.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile162 Citations (Scopus)179 Downloads (Pure) -
Genome-centric view of carbon processing in thawing permafrost
Woodcroft, B. J., Singleton, C. M., Boyd, J. A., Evans, P. N., Emerson, J. B., Zayed, A. A. F., Hoelzle, R. D., Lamberton, T. O., McCalley, C. K., Hodgkins, S. B., Wilson, R. M., Purvine, S. O., Nicora, C. D., Li, C., Frolking, S., Chanton, J. P., Crill, P. M., Saleska, S. R., Rich, V. I. & Tyson, G. W., 2 Aug 2018, In: Nature. 560, 7716, p. 49-54 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
262 Citations (Scopus) -
The novel genus, ‘Candidatus Phosphoribacter’, previously identified as Tetrasphaera, is the dominant polyphosphate accumulating lineage in EBPR wastewater treatment plants worldwide
Singleton, C. M., Petriglieri, F., Wasmund, K., Nierychlo, M., Kondrotaite, Z., Petersen, J. F., Peces, M., Dueholm, M. S., Wagner, M. & Nielsen, P. H., Jun 2022, In: ISME Journal. 16, 6, p. 1605-1616 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile46 Citations (Scopus)58 Downloads (Pure) -
A genomic view of the reef-building coral Porites lutea and its microbial symbionts
ReFuGe2020 Consortium, 1 Dec 2019, In: Nature Microbiology. 4, 12, p. 2090-2100 11 p.Research output: Contribution to journal › Letter › peer-review
158 Citations (Scopus)
Activities
- 1 Conference presentations
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MAGnifying biogas production efficiency: high-quality metagenome-assembled genome recovery in anaerobic digesters reveals abundant novel populations with key functional roles
Caitlin Margaret Singleton (Speaker), Chenjing Jiang (Other), Lei Liu (Other), Rasmus Hansen Kirkegaard (Other), Morten Kam Dahl Dueholm (Other) & Per Halkjær Nielsen (Other)
12 Sept 2023Activity: Talks and presentations › Conference presentations
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