Projects per year
Personal profile
Research profile
I am a researcher with one foot in the clinic in the Department of Hematology at Aalborg University Hospital. My research emerges from clinical challenges, and I am engaged in several epidemiological and biochemical studies of coagulation and hematological diseases, and an innovative project investigating effects of ketones in cancer treatment. My main research area is development of new, non-invasive diagnostics and monitoring of diseases and treatments by omics-analysis of the air we exhale.
My research in exhaled breath proteomics is inspired from my clinical work, where I often deal with acute medical conditions in fragile patients.
With +10 years of experience with collection and analysis of exhaled breath samples, I have demonstrated that the air we exhale contains endogenous proteins from a broad variety of biological processes in our bodies. I think of our exhaled breath as a biological sample, just like a blood sample, but with the great benefits of non-invasive collection (as we must breathe anyway) and potential for continuous sample collection.
I lead the Exhaled Breath Diagnostics and Monitoring research group (ExBreDia) in the Department of Hematology at Aalborg University hospital. The research group was established with a Clinical Emerging Investigator grant from the Novo Nordisk Foundation in 2024. As investigation of non-volatile organic compounds in the exhaled breath is still an emerging field of research, the research group focuses on method optimization and investigation of the potential for rapid diagnostics in various types of medical conditions to find the most promising paths to clinical implementation.
Throughout the years, I have been actively engaged with industrial and academic collaborators to improve exhaled breath collection and analysis, leading to advancements in equipment and methodologies opening a novel research avenue for identifying biomarkers with the potential to transform point-of-care diagnostics and monitoring. My ultimate research aim is the application of non-invasive exhaled breath precision diagnostic and monitoring methods for the benefit of both patients and society.
PhD Supervision
PhD main supervisor for Sophie Rex Christensen, 2025 -
PhD co-supervisor for Jesper Erik Karl Strandberg, 2020 -
PhD co-supervisor for Jennifer Bøgh, Department of Clinical Medicine, Århus University, 2024 -
Moderator of the PhD defence by Mia Solholt Godthaab Brath, 2024
PhD predefence chairman for Andreas Øvlisen, 2019 and Line Bjerrehave Nielsen, 2023
Teaching profile
I teach medical students at master level. With PBL as take-off, I use cases from my own clinical practice in both case - and formal classes. I mainly cover lymphoproliferative diseases, anemia and acute hematological conditions.
I have been supervising several student projects, please see the up-loaded portfoli for furter information, and keep an eye on the project catalogue for projects from the ExBreDia group.
Administrative profile
2024: Medstifter af Netværk for Kliniske Lektorer ved Aalborg Universitet, forperson for forskningsudvalget herunder.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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- 1 Similar Profiles
Collaborations from the last five years
Projects
- 5 Active
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Exhaled Breath Collector
Gade, I. L. (PI), Rex Christensen, S. (CoI), Rees, S. E. (CoI) & Honoré, B. (CoI)
01/09/2025 → …
Project: Other
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Exploring exhaled breath biomarkers for non-invasive diagnostics showcased by stroke and pulmonary embolism
Gade, I. L. (PI), Kjærgaard, B. (CoPI), Modrau, B. (CoPI), Rees, S. E. (CoI) & Honoré, B. (CoPI)
01/02/2025 → …
Project: Research
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NILEX: Non-invasive Diagnosis of Pulmonary Embolism by use of Biomarkers in Exhaled Breath
Gade, I. L. (PI), Honoré, B. (CoPI), Krarup, A. L. (Project Participant), Roed, M. L. (Project Participant) & Kristensen, S. R. (CoPI)
01/02/2024 → …
Project: Research
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Exhaled breath protein composition in patients
Gade, I. L. (PI), Bennike, T. B. (PI), Kristensen, S. R. (PI) & Honoré, B. (PI)
01/02/2024 → …
Project: Research
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NIPA: Non-invasive Diagnosis of Invasive Pulmonary Aspergillosis by use of Biomarkers in Exhaled Breath Condensate
Gade, I. L. (PI) & Honoré, B. (CoI)
Independent Research Fund Denmark
01/02/2023 → 31/01/2026
Project: Research
Research output
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A systematic review of the exhaled breaths protein composition
Pedersen, J. L., Christensen, S. R., Bennike, T. B., Honoré, B. & Gade, I. L., 2025, Breath Summit 2025: Conference Programme and Book of Abstracts. Innsbruck, Austria, p. 177-178 1 p.Research output: Contribution to book/anthology/report/conference proceeding › Conference abstract in proceeding › Research › peer-review
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Detection of pathogenic DNA in exhaled breath condensate using Pneumocystis jirovecii as example
Christensen, S. R., Lundsted, D. H., Nørholt, D. H., Jensen, E., Wittrup, J. H., Abou-Harb, J., Stentoft, V. D. F. & Gade, I. L., 2025, Breath Summit 2025 : Conference Programme and Book of Abstracts. Innsbruck, Austria, p. 109-110 2 p.Research output: Contribution to book/anthology/report/conference proceeding › Conference abstract in proceeding › Research › peer-review
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Exhaled breath protein composition in patients hospitalised during the first wave of COVID-19
Gade, I. L., Bodilsen, J., Mariager, T., Hertz, S., Duerlund, L. S. S., Holm, C. K., Madsen, P. H., Bennike, T. B. & Honoré, B., 1 Jul 2025, In: Journal of Breath Research. 19, 3, 036008.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile12 Downloads (Pure) -
Forsøgsprotokollen
El-Galaly, T. C., Gade, I. L. & Jensen, P., 2025, Kliniske lægemiddelforsøg. Johnsen, S., Hansen, L. & Klokker, D. (eds.). 1. ed. FADL's Forlag a/s, p. 32-42 11 p.Research output: Contribution to book/anthology/report/conference proceeding › Book chapter › Education › peer-review
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Increased contact system activity three months after starting combined oral contraceptives
Strandberg, J., Nybo, J., Gade, I. L., Palarasah, Y., Bladbjerg, E.-M. & Kristensen, S. R., Sept 2025, In: Thrombosis Research. 253, 5 p., 109428.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile
Activities
- 1 Conference presentations
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Bottom-up proteomic analysis of the exhaled breath condensate from twenty-six individual healthy persons
Gade, I. L. (Lecturer), Bennike, T. B. (Lecturer), Kristensen, S. R. (Other) & Honoré, B. (Other)
14 Jun 2022Activity: Talks and presentations › Conference presentations
Press/Media
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Udåndingsluft kan blive en værdifuld diagnostisk metode
Gade, I. L. & Kristensen, S. R.
14/04/2023
1 item of Media coverage
Press/Media: Press / Media
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Brok ved morgenkonferencen kan blive til bud på nye løsninger
Jørgensen , C. H., Driever, C. D., Gade, I. L., Huus Pedersen, S., Siggaard, L. D., Hviid, C. V. B. & Abood, A.A.-H.
14/04/2023
1 item of Media coverage
Press/Media: Press / Media
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Priser til fire lægelige talenter
Gade, I. L., Petersen, C. N., Holm, K. F. & Sørensen Bork, C.
02/11/2020
1 item of Media coverage
Press/Media: Press / Media
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Priser til fire lægelige ildsjæle
Holm, K. F., Petersen, C. N., Gade, I. L. & Sørensen Bork, C.
24/10/2020
1 item of Media coverage
Press/Media: Press / Media
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Ny viden om behandling for akut blodprop i lungerne
22/11/2019
1 item of Media coverage
Press/Media: Press / Media