Karen Dybkær

2024

A systematic literature review on clonal evolution events preceding relapse in multiple myeloma

Jakobsen, M. Z., Brøndum, R. F., Gregersen, H., Due, H. & Dybkær, K., Jan 2025, In: Critical Reviews in Oncology/Hematology. 205, 16 p., 104560.

Research output: Contribution to journal › Review article › peer-review

Open Access

CRISPR-Cas9 Knockout Screens Identify DNA Damage Response Pathways and BTK as Essential for Cisplatin Response in Diffuse Large B-Cell Lymphoma

Issa, I. I., Due, H., Brøndum, R. F., Veeravakaran, V., Haraldsdóttir, H., Sylvester, C., Brogaard, A., Dhanjal, S., Schmierer, B. & Dybkær, K., 2 Jul 2024, In: Cancers. 16, 13, 2437.

Research output: Contribution to journal › Journal article › Research › peer-review

Open Access

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1 Citation (Scopus)

21 Downloads (Pure)

DNA mismatch repair defect and intratumor heterogeneous deficiency differently impact immune responses in diffuse large B-cell lymphoma

Xu-Monette, Z. Y., Luo, C., Yu, L., Li, Y., Bhagat, G., Tzankov, A., Visco, C., Fan, X., Dybkaer, K., Sakhdari, A., Wang, N. T., Yuan, A. F., Chiu, A., Tam, W., Zu, Y., Hsi, E. D., Perry, A. M., Song, W., O'Malley, D. & Au, Q. & 11 others, Nunns, H., Go, H., Møller, M. B., Parsons, B. M., Montes-Moreno, S., Ponzoni, M., Ferreri, A. J. M., Sohani, A. R., Abramson, J. S., Xu, B. & Young, K. H., Aug 2024, In: OncoImmunology. 13, 1, 13 p., 2384667.

Research output: Contribution to journal › Journal article › Research › peer-review

Open Access

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6 Downloads (Pure)

The Prognostic Potential of circRNAs in Multiple Myeloma: Insights From Whole Bone Marrow and Purified Plasma Cells

Jakobsen, T., Pløen, G. G., Behsen, A. D., Møller, H. J., Plesner, T., Dybkær, K., Andersen, M. N., Misund, K. & Kristensen, L. S., Nov 2024, In: Journal of Cellular and Molecular Medicine. 28, 22, 14 p., e70215.

Research output: Contribution to journal › Journal article › Research › peer-review

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2023

An Aggressive Course of Transformed Splenic Diffuse Red Pulp Small B-Cell Lymphoma With Novel Somatic Loss-of-Function Mutation in RB1

Christensen, L.-M., Severinsen, M. T., Katoch, P., Ovlisen, A. K., Hoyer, T., Jensen, P., Dybkaer, K. & Kristensen, D. T., Jun 2023, In: Journal of Hematology. 12, 3, p. 118-122 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

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50 Downloads (Pure)

Annual report 2022: Department of Haematology

Severinsen, M. T. (Editor), Dybkær, K. (Editor), Bøgsted, M. (Editor), El-Galaly, T. C. (Editor), Gulbæk, M. (Editor), Gregersen, H. (Editor), Hansen, A. L. (Editor) & Elkjær, L. T. (Editor), May 2023, Aalborg Universitetshospital. 28 p.

Research output: Book/Report › Report › Communication

Diffuse Large B-Cell Lymphoma Has a Low Frequency of dMMR and High Frequencies of DNA Mismatch Repair Protein High Expression Associated with Lower T-Cell Infiltration

Xu-Monette, Z. Y., Yu, L., Luo, C., Li, Y., Bhagat, G., Tzankov, A., Visco, C., Fan, X., Dybkaer, K., Sakhdari, A., Chiu, A., Tam, W., Zu, Y., Hsi, E. D., Hagemeister, F. B., O'Malley, D., Au, Q., Nunns, H., Go, H. & Ponzoni, M. & 9 others, Ferreri, A. J. M., Møller, M., Parsons, B. M., Van Krieken, J. H. J. M., Piris, M., Winter, J., Xu, B., Zhang, M. & Young, K. H., 2 Nov 2023, In: Blood. 142, Suppl. 1, p. 6079-6081 3 p.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Early diagnosis of ovarian cancer based on methylation profiles in peripheral blood cell-free DNA: a systematic review

Terp, S. K., Stoico, M. P., Dybkær, K. & Pedersen, I. S., 14 Feb 2023, In: Clinical Epigenetics. 15, 1, 17 p., 24.

Research output: Contribution to journal › Review article › peer-review

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19 Citations (Scopus)

100 Downloads (Pure)

EBV-positive DLBCL frequently harbors somatic mutations associated with clonal hematopoiesis of indeterminate potential

Li, Y., Xu-Monette, Z. Y., Abramson, J., Sohani, A., Bhagat, G., Tzankov, A., Visco, C., Zhang, S., Dybkaer, K., Pan, Z., Xu, M., Tam, W., Zu, Y., Hsi, E. D., Hagemeister, F. B., Go, H., van Krieken, J. H., Winter, J. N., Ponzoni, M. & Ferreri, A. J. M. & 5 others, Møller, M. B., Piris, M. A., Wang, Y., Zhang, M. & Young, K. H., 11 Apr 2023, In: Blood advances. 7, 7, p. 1308–1311 4 p.

Research output: Contribution to journal › Letter › peer-review

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7 Citations (Scopus)

32 Downloads (Pure)

Feasibility and early clinical impact of precision medicine for late-stage cancer patients in a regional public academic hospital

Ladekarl, M., Nøhr, A. K., Sønderkær, M., Dahl, S. C., Sunde, L., Vesteghem, C., Mapendano, C. K., Haslund, C. A., Pagh, A., Carus, A., Lörincz, T., Nowicka-Matus, K., Poulsen, L. Ø., Laursen, R. J., Dybkær, K., Poulsen, B. K., Frøkjær, J. B., Brügmann, A. H., Ernst, A. & Wanders, A. & 2 others, Bøgsted, M. & Pedersen, I. S., Mar 2023, In: Acta Oncologica. 62, 3, p. 261-271 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

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2 Citations (Scopus)

83 Downloads (Pure)

Predictive biomarkers in radioresistant rectal cancer: A systematic review

Slipsager, A., Henrichsen, S. N., Falkmer, U. G., Dybkær, K., Belting, M. & Poulsen, L. Ø., Jun 2023, In: Critical Reviews in Oncology/Hematology. 186, 6 p., 103991.

Research output: Contribution to journal › Review article › peer-review

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55 Downloads (Pure)

Resistance to vincristine in DLBCL by disruption of p53-induced cell cycle arrest and apoptosis mediated by KIF18B and USP28

Rovsing, A. B., Thomsen, E. A., Nielsen, I., Skov, T. W., Luo, Y., Dybkær, K. & Mikkelsen, J. G., Aug 2023, In: British Journal of Haematology. 202, 4, p. 825-839 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

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8 Citations (Scopus)

47 Downloads (Pure)

Tumor-infiltrating normal B cells revealed by immunoglobulin repertoire clonotype analysis are highly prognostic and crucial for antitumor immune responses in DLBCL

Xu-Monette, Z. Y., Li, Y., Snyder, T., Yu, T., Lu, T., Tzankov, A., Visco, C., Bhagat, G., Qian, W., Dybkaer, K., Chiu, A., Tam, W., Zu, Y., Hsi, E. D., Hagemeister, F. B., Wang, Y., Go, H., Ponzoni, M., Ferreri, A. J. M. & Møller, M. B. & 11 others, Parsons, B. M., Fan, X., van Krieken, J. H., Piris, M. A., Winter, J. N., Au, Q., Kirsch, I., Zhang, M., Shaughnessy, J., Xu, B. & Young, K. H., 1 Dec 2023, In: Clinical Cancer Research. 29, 23, p. 4808-4821 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

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6 Citations (Scopus)

2 Downloads (Pure)

2022

Annual report 2021: Department of Haematology

Severinsen, M. T. (Editor), Dybkær, K. (Editor), Bøgsted, M. (Editor), El-Galaly, T. C. (Editor), Gulbæk, M. (Editor), Gregersen, H. (Editor), Hansen, A. L. (Editor) & Elkjær, L. T. (Editor), Jul 2022, Aalborg Universitetshospital. 28 p.

Research output: Book/Report › Report › Communication

Determining clinical course of diffuse large B-cell lymphoma using targeted transcriptome and machine learning algorithms

Albitar, M., Zhang, H., Goy, A., Xu-Monette, Z. Y., Bhagat, G., Visco, C., Tzankov, A., Fang, X., Zhu, F., Dybkaer, K., Chiu, A., Tam, W., Zu, Y., Hsi, E. D., Hagemeister, F. B., Huh, J., Ponzoni, M., Ferreri, A. J. M., Møller, M. B. & Parsons, B. M. & 6 others, van Krieken, J. H., Piris, M. A., Winter, J. N., Li, Y., Xu, B. & Young, K. H., 1 Feb 2022, In: Blood Cancer Journal. 12, 2, 25.

Research output: Contribution to journal › Journal article › Research › peer-review

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12 Citations (Scopus)

38 Downloads (Pure)

Genetic subtyping and phenotypic characterization of the immune microenvironment and MYC/BCL2 double expression reveal heterogeneity in diffuse large B-cell lymphoma

Xu-Monette, Z. Y., Wei, L., Fang, X., Au, Q., Nunns, H., Nagy, M., Tzankov, A., Zhu, F., Visco, C., Bhagat, G., Dybkaer, K., Chiu, A., Tam, W., Zu, Y., Hsi, E. D., Hagemeister, F. B., Sun, X., Han, X., Go, H. & Ponzoni, M. & 11 others, Ferreri, A. J. M., Møller, M. B., Parsons, B. M., van Krieken, J. H., Piris, M. A., Winter, J. N., Li, Y., Xu, B., Albitar, M., You, H. & Young, K. H., 1 Mar 2022, In: Clinical Cancer Research. 28, 5, p. 972-983 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Open Access

25 Citations (Scopus)

Hsp90 inhibition sensitizes DLBCL cells to cisplatin

Schmidt, L., Issa, I. I., Haraldsdóttir, H., Hald, J. L., Schmitz, A., Due, H. & Dybkær, K., Apr 2022, In: Cancer Chemotherapy and Pharmacology. 89, 4, p. 431-440 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

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7 Citations (Scopus)

60 Downloads (Pure)

Implementing a data infrastructure for precision oncology projects leveraging REDCap

Vesteghem, C., Dahl, S. C., Brøndum, R. F., Sønderkær, M., Bødker, J. S., Schmitz, A., Weischenfeldt, J., Pedersen, I. S., Sommer, M., Rytter, A. S., Nielsen, M. M., Ladekarl, M., Severinsen, M. T., Dybkær, K., Grønbæk, K., El-Galaly, T., Roug, A. S. & Bøgsted, M., 12 May 2022, medRxiv, 20 p. (medRxiv).

Research output: Working paper/Preprint › Preprint

Longitudinal minimal residual disease assessment in multiple myeloma patients in complete remission - results from the NMSG flow-MRD substudy within the EMN02/HO95 MM trial

Schmitz, A., Brøndum, R. F., Johnsen, H. E., Mellqvist, U.-H., Waage, A., Gimsing, P., Op Bruinink, D. H., van der Velden, V., van der Holt, B., Hansson, M., Andersen, N. F., Frølund, U. C., Helleberg, C., Schjesvold, F. H., Ahlberg, L., Gulbrandsen, N., Andreasson, B., Lauri, B., Haukas, E. & Bødker, J. S. & 7 others, Roug, A. S., Bøgsted, M., Severinsen, M. T., Gregersen, H., Abildgaard, N., Sonneveld, P. & Dybkær, K., 5 Feb 2022, In: BMC Cancer. 22, 1, 147.

Research output: Contribution to journal › Journal article › Research › peer-review

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1 Citation (Scopus)

32 Downloads (Pure)

2021

A bendamustine resistance gene signature in diffuse large B-cell lymphoma and multiple myeloma

Issa, I. I., Brøndum, R. F., Due, H., Schmidt, A. L. A. M., Bøgsted, M. & Dybkær, K., 2021, In: Cancer Drug Resistance. 4, 1, p. 208-222 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

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84 Downloads (Pure)

Aggressive B-cell Lymphoma with MYC/TP53 Dual Alterations Displays Distinct Clinicopathobiological Features and Response to Novel Targeted Agents

Deng, M., Xu-Monette, Z. Y., Pham, L. V., Wang, X., Tzankov, A., Fang, X., Zhu, F., Visco, C., Bhagat, G., Dybkaer, K., Chiu, A., Tam, W., Zu, Y., Hsi, E. D., You, H., Huh, J., Ponzoni, M., Ferreri, A. J. M., Moller, M. B. & Parsons, B. M. & 8 others, Hagemeister, F., van Krieken, J. H., Piris, M. A., Winter, J. N., Li, Y., Xu, B., Liu, P. & Young, K. H., 1 Feb 2021, In: Molecular Cancer Research. 19, 2, p. 249-260 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Open Access

24 Citations (Scopus)

Aktivitetsrapport. Relapsprojektet 2015-2020: Personlig medicin ved hæmatologisk kræft

Bøgsted, M. (Editor), Führer, A., Roug, A. S., Rytter, A. S., Vesteghem, C., Høholt, H., Ildal, J., Dybkær, K., Nielsen, L. B., Elkjær, L. T., Sønderkær, M., Severinsen, M. T., Bøgsted, M., Sommer, M., Jensen, P., Blindum, P. F., Brøndum, R. F., Dahl, S. C. & El-Galaly, T. C., Mar 2021, 1 ed. Aalborg Universitetshospital. 20 p.

Research output: Book/Report › Report › Communication

Direct costs of antineoplastic and supportive treatment for progressive multiple myeloma in a tax-based health system

Brøndum, R. F., Vestergaard, A. S., Børty, L., Vesteghem, C., Rytter, A. S., Nielsen, M. M., Severinsen, M. T., Jensen, P., Gregersen, H., El-Galaly, T. C., Dybkær, K., Ehlers, L. H., Bøgsted, M. & Roug, A. S., Sept 2021, In: Future Oncology. 17, 25, p. 3331-3341 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Dynamic Intracellular Metabolic Cell Signaling Profiles During Ag-Dependent B-Cell Differentiation

Díez, P., Pérez-Andrés, M., Bøgsted, M., Azkargorta, M., García-Valiente, R., Dégano, R. M., Blanco, E., Mateos-Gomez, S., Bárcena, P., Santa Cruz, S., Góngora, R., Elortza, F., Landeira-Viñuela, A., Juanes-Velasco, P., Segura, V., Manzano-Román, R., Almeida, J., Dybkaer, K., Orfao, A. & Fuentes, M., Mar 2021, In: Frontiers in Immunology. 12, 16 p., 637832.

Research output: Contribution to journal › Journal article › Research › peer-review

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3 Citations (Scopus)

42 Downloads (Pure)

Genomic complexity is associated with epigenetic regulator mutations and poor prognosis in diffuse large B-cell lymphoma

You, H., Xu-Monette, Z. Y., Wei, L., Nunns, H., Nagy, M. L., Bhagat, G., Fang, X., Zhu, F., Visco, C., Tzankov, A., Dybkaer, K., Chiu, A., Tam, W., Zu, Y., Hsi, E. D., Hagemeister, F. B., Huh, J., Ponzoni, M., Ferreri, A. J. M. & Møller, M. B. & 9 others, Parsons, B. M., Van Krieken, J. H., Piris, M. A., Winter, J. N., Li, Y., Au, Q., Xu, B., Albitar, M. & Young, K. H., 2021, In: OncoImmunology. 10, 1, 1928365.

Research output: Contribution to journal › Journal article › Research › peer-review

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7 Citations (Scopus)

30 Downloads (Pure)

Long Non-Coding RNAs in Diffuse Large B-Cell Lymphoma

Karstensen, K. T., Schein, A., Petri, A., Bøgsted, M., Dybkær, K., Uchida, S. & Kauppinen, S., Jan 2021, In: Non-coding RNA. 7, 1, 13 p., 1.

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10 Citations (Scopus)

91 Downloads (Pure)

Optimization of Preanalytical Variables for cfDNA Processing and Detection of ctDNA in Archival Plasma Samples

Nesic, M., Bødker, J. S., Terp, S. K. & Dybkær, K., 2021, In: BioMed Research International. 2021, 5585148.

Research output: Contribution to journal › Journal article › Research › peer-review

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10 Citations (Scopus)

53 Downloads (Pure)

The mutational profile of immune surveillance genes in diagnostic and refractory/relapsed DLBCLs

Nesic, M., Sønderkær, M., Brøndum, R. F., El-Galaly, T. C., Pedersen, I. S., Bøgsted, M. & Dybkær, K., 18 Jul 2021, In: BMC Cancer. 21, 1, 12 p., 829.

Research output: Contribution to journal › Journal article › Research › peer-review

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4 Citations (Scopus)

45 Downloads (Pure)

2020

A refined cell-of-origin classifier with targeted NGS and artificial intelligence shows robust predictive value in DLBCL

Xu-Monette, Z. Y., Zhang, H., Zhu, F., Tzankov, A., Bhagat, G., Visco, C., Dybkaer, K., Chiu, A., Tam, W., Zu, Y., Hsi, E. D., You, H., Huh, J., Ponzoni, M., Ferreri, A. J. M., Møller, M. B., Parsons, B. M., van Krieken, J. H., Piris, M. A. & Winter, J. N. & 8 others, Hagemeister, F. B., Shahbaba, B., De Dios, I., Zhang, H., Li, Y., Xu, B., Albitar, M. & Young, K. H., 28 Jul 2020, In: Blood advances. 4, 14, p. 3391-3404 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

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26 Citations (Scopus)

44 Downloads (Pure)

Development of a Precision Medicine Workflow in Hematological Cancers, Aalborg University Hospital, Denmark

Bødker, J. S., Sønderkær, M., Vesteghem, C., Schmitz, A., Brøndum, R. F., Sommer, M., Rytter, A. S., Nielsen, M. M., Madsen, J., Jensen, P., Pedersen, I. S., Grubach, L., Severinsen, M. T., Roug, A. S., El-Galaly, T. C., Dybkær, K. & Bøgsted, M., Feb 2020, In: Cancers. 12, 2, 23 p., 312.

Research output: Contribution to journal › Journal article › Research › peer-review

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10 Citations (Scopus)

132 Downloads (Pure)

DNA methylation biomarkers in peripheral blood of patients with head and neck squamous cell carcinomas. A systematic review

Danstrup, C. S., Marcussen, M., Pedersen, I. S., Jacobsen, H., Dybkær, K. & Gaihede, M., 17 Dec 2020, In: PLOS ONE. 15, 12, e0244101.

Research output: Contribution to journal › Review article › peer-review

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8 Citations (Scopus)

85 Downloads (Pure)

Identification of BLNK and BTK as mediators of rituximab-induced programmed cell death by CRISPR screens in GCB-subtype diffuse large B-cell lymphoma

Thomsen, E. A., Rovsing, A. B., Anderson, M. V., Due, H., Huang, J., Luo, Y., Dybkær, K. & Mikkelsen, J. G., 1 Sept 2020, In: Molecular Oncology. 14, 9, p. 1978-1997 20 p.

Research output: Contribution to journal › Journal article › Research › peer-review

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17 Citations (Scopus)

82 Downloads (Pure)

Implementing the FAIR Data Principles in precision oncology: review of supporting initiatives

Vesteghem, C., Brøndum, R. F., Sønderkær, M., Sommer, M., Schmitz, A., Bødker, J. S., Dybkær, K., El-Galaly, T. C. & Bøgsted, M., May 2020, In: Briefings in Bioinformatics. 21, 3, p. 936–945 10 p.

Research output: Contribution to journal › Review article › peer-review

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40 Citations (Scopus)

129 Downloads (Pure)

MicroRNAs associated to single drug components of R-CHOP identifies diffuse large B-cell lymphoma patients with poor outcome and adds prognostic value to the international prognostic index

Due, H., Brøndum, R. F., Young, K. H., Bøgsted, M. & Dybkær, K., 20 Mar 2020, In: BMC Cancer. 20, 1, 12 p., 237.

Research output: Contribution to journal › Journal article › Research › peer-review

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11 Citations (Scopus)

80 Downloads (Pure)

Mutational landscape of immune surveillance genes in diffuse large B-cell lymphoma

Nesic, M., El-Galaly, T. C., Bøgsted, M., Pedersen, I. S. & Dybkær, K., 2020, In: Expert Review of Hematology. 13, 6, p. 655-668 14 p.

Research output: Contribution to journal › Review article › peer-review

2 Citations (Scopus)

Når medicinen bliver personlig

Dybkær, K. (Producer) & Krarup, H. B. (Producer), Mar 2020

Research output: Non-textual form › Sound/Visual production (digital) › Communication

Open Access

Normal myeloid progenitor cell subset-associated gene signatures for acute myeloid leukaemia subtyping with prognostic impact

Schönherz, A. A., Bødker, J. S., Schmitz, A., Brøndum, R. F., Jakobsen, L. H., Roug, A. S., Severinsen, M. T., El-Galaly, T. C., Jensen, P., Johnsen, H. E., Bøgsted, M. & Dybkær, K., Apr 2020, In: PLOS ONE. 15, 4, p. 1-21 21 p., e0229593.

Research output: Contribution to journal › Journal article › Research › peer-review

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3 Citations (Scopus)

86 Downloads (Pure)

XPO1 expression worsens the prognosis of unfavorable DLBCL that can be effectively targeted by selinexor in the absence of mutant p53

Deng, M., Zhang, M., Xu-Monette, Z. Y., Pham, L. V., Tzankov, A., Visco, C., Fang, X., Bhagat, G., Zhu, F., Dybkaer, K., Chiu, A., Tam, W., Zu, Y., Hsi, E. D., Choi, W. W. L., Huh, J., Ponzoni, M., Ferreri, A. J. M., Møller, M. B. & Parsons, B. M. & 9 others, van Krieken, J. H., Piris, M. A., Winter, J. N., Hagemeister, F., Alinari, L., Li, Y., Andreeff, M., Xu, B. & Young, K. H., 1 Dec 2020, In: Journal of Hematology & Oncology. 13, 1, 148.

Research output: Contribution to journal › Letter › peer-review

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32 Citations (Scopus)

39 Downloads (Pure)

2019

Aspects of vincristine-induced neuropathy in hematologic malignancies: a systematic review

Madsen, M. L., Due, H., Ejskjær, N., Jensen, P., Madsen, J. & Dybkær, K., 1 Sept 2019, In: Cancer Chemotherapy and Pharmacology. 84, 3, p. 471–485 15 p.

Research output: Contribution to journal › Review article › peer-review

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89 Citations (Scopus)

227 Downloads (Pure)

Expression of NOTCH3 exon 16 differentiates Diffuse Large B-cell Lymphoma into molecular subtypes and is associated with prognosis

Jespersen, D. S., Schönherz, A. A., Due, H., Bøgsted, M., Sondergaard, T. E. & Dybkær, K., Jan 2019, In: Scientific Reports. 9, 1, 335.

Research output: Contribution to journal › Journal article › Research › peer-review

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6 Citations (Scopus)

224 Downloads (Pure)

High CXCR4 expression impairs rituximab response and the prognosis of R-CHOP-treated diffuse large B-cell lymphoma patients

Laursen, M. B., Reinholdt, L., Schönherz, A. A., Due, H., Jespersen, D. S., Grubach, L., Ettrup, M. S., Røge, R., Falgreen, S., Sørensen, S., Bødker, J. S., Schmitz, A., Johnsen, H. E., Bøgsted, M. & Dybkær, K., 22 Jan 2019, In: Oncotarget. 10, 7, p. 717-731 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

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21 Citations (Scopus)

127 Downloads (Pure)

High-throughput sequencing-based investigation of viruses in human cancers by multi-enrichment approach

Mollerup, S., Asplund, M., Friis-Nielsen, J., Kjartansdóttir, K. R., Fridholm, H., Hansen, T. A., Herrera, J. A. R., Barnes, C. J., Jensen, R. H., Richter, S. R., Nielsen, I. B., Pietroni, C., Alquezar-Planas, D. E., Rey-Iglesia, A., Olsen, P. V. S., De Meyts, E.R., Groth-Pedersen, L., von Buchwald, C., Jensen, D. H. & Gniadecki, R. & 20 others, Høgdall, E., Langhoff, J. L., Pete, I., Vereczkey, I., Baranyai, Z., Dybkaer, K., Johnsen, H. E., Steiniche, T., Hokland, P., Rosenberg, J., Baandrup, U., Sicheritz-Pontén, T., Willerslev, E., Brunak, S., Lund, O., Mourier, T., Vinner, L., Izarzugaza, J. M. G., Nielsen, L. P. & Hansen, A. J., Oct 2019, In: The Journal of Infectious Diseases. 220, 8, p. 1312-1324 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

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13 Citations (Scopus)

57 Downloads (Pure)

Immune Profiling and Quantitative Analysis Decipher the Clinical Role of Immune-Checkpoint Expression in the Tumor Immune Microenvironment of DLBCL

Xu-Monette, Z. Y., Xiao, M., Au, Q., Padmanabhan, R., Xu, B., Hoe, N., Rodríguez-Perales, S., Torres-Ruiz, R., Manyam, G. C., Visco, C., Miao, Y., Tan, X., Zhang, H., Tzankov, A., Wang, J., Dybkær, K., Tam, W., You, H., Bhagat, G. & Hsi, E. D. & 13 others, Ponzoni, M., Ferreri, A. J. M., Møller, M. B., Piris, M. A., van Krieken, J. H., Winter, J. N., Westin, J. R., Pham, L. V., Medeiros, L. J., Rassidakis, G. Z., Li, Y., Freeman, G. J. & Young, K. H., 1 Apr 2019, In: Cancer Immunology Research. 7, 4, p. 644-657 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

110 Citations (Scopus)

Immunoglobulin somatic hypermutation has clinical impact in DLBCL and potential implications for immune checkpoint blockade and neoantigen-based immunotherapies

Xu-Monette, Z. Y., Li, J., Xia, Y., Crossley, B., Bremel, R. D., Miao, Y., Xiao, M., Snyder, T., Manyam, G. C., Tan, X., Zhang, H., Visco, C., Tzankov, A., Dybkaer, K., Bhagat, G., Tam, W., You, H., Hsi, E. D., van Krieken, J. H. & Huh, J. & 10 others, Ponzoni, M., Ferreri, A. J. M., Møller, M. B., Piris, M. A., Winter, J. N., Medeiros, J. T., Xu, B., Li, Y., Kirsch, I. & Young, K. H., Oct 2019, In: Journal for immunotherapy of cancer. 7, 1, p. 1-15 15 p., 272.

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Open Access

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22 Citations (Scopus)

55 Downloads (Pure)

MicroRNA-155 controls vincristine sensitivity and predicts superior clinical outcome in diffuse large B-cell lymphoma

Due, H., Schönherz, A. A., Ryø, L., Primo, M. N., Jespersen, D. S., Thomsen, E. A., Roug, A. S., Xiao, M., Tan, X., Pang, Y., Young, K. H., Bøgsted, M., Mikkelsen, J. G. & Dybkær, K., 9 Apr 2019, In: Blood advances. 3, 7, p. 1185-1196 12 p.

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Open Access

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23 Citations (Scopus)

149 Downloads (Pure)

NEXT Bioinformatics: Activity Report: 2015 - 2018

Bøgsted, M. (Member of study group), Dybkær, K. (Member of study group), Johnsen, H. E. (Member of study group), Brøndum, R. F. (Member of study group), Vesteghem, C. (Member of study group), Pedersen, A. S. (Member of study group), Sønderkær, M. (Member of study group), Jakobsen, L. H. (Member of study group), Schönherz, A. A. (Member of study group), Bilgrau, A. E. (Member of study group), Bødker, J. S. (Member of study group), Have, J. (Member of study group), Nielsen, K. L. (Member of study group), Weerdt, D. (Member of study group) & Deltagere fra Aalborg Universitetshospital/Aalborg Universitet, Feb 2019, 28 p.

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PD-1/PD-L1 expression and interaction by automated quantitative immunofluorescent analysis show adverse prognostic impact in patients with diffuse large B-cell lymphoma having T-cell infiltration: a study from the International DLBCL Consortium Program

Li, L., Sun, R., Miao, Y., Tran, T., Adams, L., Roscoe, N., Xu, B., Manyam, G. C., Tan, X., Zhang, H., Xiao, M., Tzankov, A., Visco, C., Dybkaer, K., Bhagat, G., Tam, W., Hsi, E. D., van Krieken, J. H., You, H. & Huh, J. & 13 others, Ponzoni, M., Ferreri, A. J. M., Møller, M. B., Piris, M. A., Zhang, M., Winter, J. N., Medeiros, L. J., Rassidakis, G. Z., Vaupel, C. A., Li, Y., Dakappagari, N., Xu-Monette, Z. Y. & Young, K. H., Jun 2019, In: Modern Pathology. 32, 6, p. 741-754 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

42 Citations (Scopus)

2018

A B-cell-associated gene signature classification of diffuse large B-cell lymphoma by NanoString technology

Michaelsen, T. Y., Richter, J., Brøndum, R. F., Klapper, W., Johnsen, H. E., Albertsen, M., Dybkær, K. & Bøgsted, M., 2018, In: Blood advances. 2, 13, p. 1542-1546 5 p.

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Open Access

11 Citations (Scopus)

A multiple myeloma classification system that associates normal B-cell subset phenotypes with prognosis

Bødker, J. S., Brøndum, R. F., Schmitz, A., Schönherz, A. A., Jespersen, D. S., Sønderkær, M., Vesteghem, C., Due, H., Nørgaard, C. H., Perez-Andres, M., Samur, M. K., Davies, F., Walker, B., Pawlyn, C., Kaiser, M., Johnson, D., Bertsch, U., Broyl, A., van Duin, M. & Shah, R. & 12 others, Johansen, P., Nørgaard, M. A., Samworth, R. J., Sonneveld, P., Goldschmidt, H., Morgan, G. J., Orfao, A., Munshi, N., Johnsen, H. E., El-Galaly, T., Dybkær, K. & Bøgsted, M., 2018, In: Blood advances. 2, 18, p. 2400-2411 12 p.

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3 Citations (Scopus)

BAGS2Clinic: et let-anvendeligt genassay til klassifikation af diffus storcellet B-celle lymfom

Michaelsen, T. Y., Dybkær, K. & Bøgsted, M., Mar 2018, In: Best Practice - Hæmatologi. 8, 23, p. 18-21 4 p.

Research output: Contribution to journal › Journal article › Communication

Karen Dybkær

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