Research output per year
Research output per year
Research output
- 41 results
Search results
-
2023
A novel strategy for delivering Niemann-Pick type C2 proteins across the blood-brain barrier using the brain endothelial-specific AAV-BR1 virus
Rasmussen, C. L. M., Hede, E., Routhe, L. J., Körbelin, J., Helgudottir, S. S., Thomsen, L. B., Schwaninger, M., Burkhart, A. & Moos, T., Jan 2023, In: Journal of Neurochemistry. 164, 1, p. 6-28 23 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile5 Citations (Scopus)47 Downloads (Pure) -
The Npc2Gt(LST105)BygNya mouse signifies pathological changes comparable to human Niemann-Pick type C2 disease
Rasmussen, C. L. M., Thomsen, L. B., Heegaard, C. W., Moos, T. & Burkhart, A., Sept 2023, In: Molecular and Cellular Neuroscience. 126, 103880.Research output: Contribution to journal › Journal article › Research › peer-review
1 Citation (Scopus) -
2021
The blood-brain barrier studied in vitro across species
Thomsen, M. S., Humle, N., Hede, E., Moos, T., Burkhart, A. & Thomsen, L. B., 12 Mar 2021, In: PLOS ONE. 16, 3, e0236770.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile39 Citations (Scopus)82 Downloads (Pure) -
2019
Evaluation of Targeted Delivery to the Brain Using Magnetic Immunoliposomes and Magnetic Force
Thomsen, L. B., Linemann, T., Birkelund, S., Tarp, G. A. & Moos, T., 31 Oct 2019, In: Materials. 12, 21, 3576.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile21 Citations (Scopus)136 Downloads (Pure) -
Targeting the transferrin receptor for brain drug delivery
Bendix Johnsen, K., Burkhart, A., Bohn Thomsen, L., Andresen, T. L. & Moos, T., 1 Oct 2019, In: Progress in Neurobiology. 181, 101665.Research output: Contribution to journal › Review article › peer-review
Open AccessFile214 Citations (Scopus)1549 Downloads (Pure) -
2018
Drug delivery to the brain: How to overcome the blood-brain barrier?
Thomsen, L. B., Jan 2018, In: Journal of Self-Assembly and Molecular Electronics. 6, Suppl. 1, p. 1-1 1 p., 4.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
Open Access -
The endo-lysosomal system of brain endothelial cells is influenced by astrocytes in vitro
Toth, A. E., Siupka, P., P Augustine, T. J., Venø, S. T., Thomsen, L. B., Moos, T., Lohi, H. T., Madsen, P., Lykke-Hartmann, K. & Nielsen, M. S., Nov 2018, In: Molecular Neurobiology. 55, 11, p. 8522-8537 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
11 Citations (Scopus) -
2017
Bidirectional apical-basal traffic of the cation-independent mannose-6-phosphate receptor in brain endothelial cells
Siupka, P., Hersom, M. N. S., Lykke-Hartmann, K., Johnsen, K. B., Thomsen, L. B., Andresen, T. L., Moos, T., Abbott, N. J., Brodin, B. & Nielsen, M. S., 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 7, p. 2598–2613Research output: Contribution to journal › Journal article › Research › peer-review
20 Citations (Scopus) -
Transfection of primary brain capillary endothelial cells for protein synthesis and secretion of recombinant erythropoietin: a strategy to enable protein delivery to the brain
Larsen, A. B., Andresen, T. L., Aigner, A., Thomsen, L. B. & Moos, T., 2017, In: Cellular and Molecular Life Sciences. 74, 13, p. 2467-2485Research output: Contribution to journal › Journal article › Research › peer-review
13 Citations (Scopus) -
2016
A triple co-culture model of the blood-brain barrier using primary porcine brain endothelial cells, porcine pericytes and porcine astrocytes
Thomsen, L. B. (Inventor), Larsen, A. B. (Inventor) & Moos, T. (Inventor), 2016, IPC No. C12N 5/071 (2010.01), C12N 5/079 (2010.01), G01N 33/50 (2006.01), Patent No. WO/2016/202343 , 22 Dec 2016, Priority date 16 Jun 2016, Priority No. PCT/DK2016/050190Research output: Patent
Open Access -
Expression of iron-related proteins at the neurovascular unit supports reduction and reoxidation of iron for transport through the blood-brain barrier
Burkhart, A., Skjørringe, T., Johnsen, K. B., Siupka, P., Thomsen, L. B., Nielsen, M. S., Thomsen, L. L. & Moos, T., 2016, In: Molecular Neurobiology. 53, 10, p. 7237-7253Research output: Contribution to journal › Journal article › Research › peer-review
78 Citations (Scopus) -
Targeted vascular drug delivery in cerebral cancer
Humle, N., Johnsen, K. B., Arendt, G. A., Nielsen, R. P., Moos, T. & Thomsen, L. B., 2016, In: Current Pharmaceutical Design. 22, 35, p. 5487-5504Research output: Contribution to journal › Review article › peer-review
8 Citations (Scopus) -
Trafficking of Transferrin Receptor in primary porcine brain endothelial cells and its implication for drug delivery to the brain
Siupka, P., Thomsen, L. B., Lykke-Hartmann, K., Moos, T. & Nielsen, M. S., 2016, Final Programme, 19th International Symposium on Signal Transduction at the Blood-Brain Barriers, 14-16 September 2016, Copenhagen, Denmark. University of Copenhagen, p. 27 O-9Research output: Contribution to book/anthology/report/conference proceeding › Conference abstract in proceeding › Research › peer-review
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Vesicular transport in brain microvascular endothelial cells
Toth, A., Siupka, P., Pulikotial, A. T., Thomsen, L. B., Lohi, H. T., Lykke-Hartmann, K., Moos, T., Madsen, P. & Nielsen, M. S., 2016, Final Programme, 19th International Symposium on Signal Transduction at the Blood-Brain Barriers, 14-16 September 2016, Copenhagen, Denmark. University of Copenhagen, p. 42-43 P-29Research output: Contribution to book/anthology/report/conference proceeding › Conference abstract in proceeding › Research › peer-review
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2015
A triple culture model of the blood-brain barrier using porcine brain endothelial cells, astrocytes and pericytes
Thomsen, L. B., Burkhart, A. & Moos, T., 2015, In: PLOS ONE. 10, 8, 16 p., e0134765.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile115 Citations (Scopus)369 Downloads (Pure) -
Repercussions of glioblastoma multiforme on the blood-brain barrier
Humle, N. H., Thomsen, L. B. & Moos, T., 2015, In: Clinical Neuropathology. 34, 3, p. 149Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
Open Access -
Targeted drug delivery to the brain using magnetic nanoparticles
Thomsen, L. B., Thomsen, M. S. & Moos, T., 2015, In: Therapeutic Delivery. 6, 10, p. 1145-1155Research output: Contribution to journal › Journal article › Research › peer-review
81 Citations (Scopus) -
Transfection of brain capillary endothelial cells in primary culture with defined blood-brain barrier properties
Larsen, A. B., Thomsen, L. B., Thomsen, M. S., Lichota, J., Fazakas, C., Krizbai, I. & Moos, T., 2015, In: Fluids and Barriers of the CNS. 12, 1, 14 p., 19.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile44 Citations (Scopus)382 Downloads (Pure) -
2014
Accessing targeted nanoparticles to the brain: the vascular route
Burkhart, A., Azizi, M., Thomsen, M. S., Thomsen, L. B. & Moos, T., 2014, In: Current Medicinal Chemistry. 21, 36, p. 4092-4099Research output: Contribution to journal › Journal article › Research › peer-review
12 Citations (Scopus) -
Gene delivery of therapeutic polypeptides to brain capillary endothelial cells for protein secretion
Larsen, A. B., Thomsen, L. B. & Moos, T., 2014.Research output: Contribution to conference without publisher/journal › Conference abstract for conference › Research › peer-review
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Iron uptake and transport at the blood-brain barrier
Larsen, A. B., Thomsen, L. B. & Moos, T., 2014.Research output: Contribution to conference without publisher/journal › Conference abstract for conference › Research › peer-review
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2013
Characterisation of an in vitro blood-brain barrier model based on primary porcine capillary endothelial cells in monoculture or co-culture with primary rat or porcine astrocytes and pericytes.
Thomsen, L. B., Larsen, A. B. & Moos, T., 2013.Research output: Contribution to conference without publisher/journal › Conference abstract for conference › Research › peer-review
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Development of a Novel Lipophilic, Magnetic Nanoparticle for in Vivo Drug Delivery
Linemann, T., Thomsen, L. B., du Jardin , K. G., Laursen, J. C., Jensen, J. B., Lichota, J. & Moos, T., 2013, In: Pharmaceutics. 5, 2, p. 246-260Research output: Contribution to journal › Journal article › Research › peer-review
13 Citations (Scopus) -
Transfection of rat brain endothelium in a primary culture model of the blood-brain barrier at different states of barrier maturity
Larsen, A. B., Thomsen, L. B., Lichota, J. & Moos, T., 2013.Research output: Contribution to conference without publisher/journal › Conference abstract for conference › Research › peer-review
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Uptake and transport of superparamagnetic iron oxide nanoparticles through human brain capillary endothelial cells
Thomsen, L. B., Linemann, T., Pondman, K. M., Lichota, J., Kim, K. S., Pieters, R. J., Visser, G. M. & Moos, T., 2013, In: ACS Chemical Neuroscience. 4, 10, p. 1352-1360Research output: Contribution to journal › Journal article › Research › peer-review
74 Citations (Scopus) -
2012
Brain delivery systems via mechanism independent of receptor-mediated endocytosis and adsorptive-mediated endocytosis
Thomsen, L. B., Lichota, J., Eskehave, T. N., Linemann, T., Mortensen , J. H., du Jardin , K. G. & Moos, T., 2012, In: Current Pharmaceutical Biotechnology. 13, 12, p. 2349-2354Research output: Contribution to journal › Journal article › Research › peer-review
15 Citations (Scopus) -
Gene delivery into primary brain capillary endothelial cells for protein secretion: a novel strategy for drug delivery to the brain
Larsen, A. B., Thomsen, L. B., Lichota, J. & Moos, T., 2012.Research output: Contribution to conference without publisher/journal › Conference abstract for conference › Research › peer-review
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Gene delivery to the blood-brain barrier: non-viral gene carriers and in vitro blood-brain barrier models
Thomsen, L. B., 2012, River Publishers.Research output: Book/Report › Book › Research › peer-review
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In vitro delivery of superparamagnetic iron oxide nanoparticles through human brain capillary endothelial cells
Thomsen, L. B., Linemann, T., Lichota, J., Visser, G., Moos, T. & Kim, K. S., 2012.Research output: Contribution to conference without publisher/journal › Conference abstract for conference › Research › peer-review
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2011
Gene delivery by pullulan derivatives in brain capillary endothelial cells for protein secretion
Thomsen, L. B., Lichota, J., Kim, K. S. & Moos, T., 2011, In: Journal of Controlled Release. 151, 1, p. 45-50Research output: Contribution to journal › Journal article › Research › peer-review
65 Citations (Scopus) -
Gene delivery of therapeutic polypeptides into brain capillary endothelial cells for protein secretion
Larsen, A. B., Thomsen, L. B., Moos, T. & Lichota, J., 2011.Research output: Contribution to conference without publisher/journal › Conference abstract for conference › Research › peer-review
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Gene delivery of therapeutic polypeptides into brain capillary endothelial cells for protein secretion
Moos, T., Larsen, A. B., Thomsen, L. B. & Lichota, J., 2011.Research output: Contribution to conference without publisher/journal › Conference abstract for conference › Research › peer-review
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Macromolecular drug transport into the brain using targeted therapy
Thomsen, L. B. & Moos, T., 2011.Research output: Contribution to conference without publisher/journal › Conference abstract for conference › Research › peer-review
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Magnetic nanoparticles: a new drug-carrier approach
Thomsen, L. B., Lichota, J., Larsen, T. E., Linemann, T., Mortensen , J. H., du Jardin , K. G. & Moos, T., 2011.Research output: Contribution to conference without publisher/journal › Conference abstract for conference › Research › peer-review
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Magnetic nanoparticles: a new drug delivery approach
Thomsen, L. B., Lichota, J., Mortensen , J. H., du Jardin , K. G., Linemann, T., Eskehave, T. N., Kim, K. S., Visser, G. & Moos, T., 2011.Research output: Contribution to conference without publisher/journal › Conference abstract for conference › Research › peer-review
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Nanoparticle-derived non-viral genetic transfection at the blood-brain barrier to enable neuronal growth factor delivery by secretion from brain endothelium
Thomsen, L. B., Larsen, A. B., Lichota, J. & Moos, T., 2011, In: Current Medicinal Chemistry. 18, 22, p. 3330-3334Research output: Contribution to journal › Journal article › Research › peer-review
10 Citations (Scopus) -
2010
Macromolecular drug transport into the brain using targeted therapy
Lichota, J., Skjørringe, T., Thomsen, L. B. & Moos, T., 2010, In: Journal of Neurochemistry. 113, 1, p. 1-13 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
67 Citations (Scopus) -
Presynaptic calcium signalling in cerebellar mossy fibres
Thomsen, L. B., Jörntell, H. & Midtgaard, J., 2010, In: Frontiers in Neural Circuits. 4, p. Article No. 1 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
6 Citations (Scopus) -
2009
Non-viral gene delivery to rat brain capillary endothelial cells using spermine-derivatives of pullulan
Lichota, J., Thomsen, L. B. & Moos, T., 2009, 39th Annual Meeting of the Society for Neuroscience, Neuroscience 2009, 17-21 October 2009, Chicago, USA. p. No. 685.8/GG118Research output: Contribution to book/anthology/report/conference proceeding › Conference abstract in proceeding › Research
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2007
Presynaptic calcium signalling in cerebellar mossy fibers
Thomsen, L. B., Yde, P., Nielsen, B. & Midtgaard, J., 2007.Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review