Projects per year
Personal profile
Research profile
My research field is molecular bacterial pathogenesis, specifically in bacterial interaction with both the innate and adaptive immune systems. Recently the focus is on the activation of the complement system by Klebsiella pneumoniae in the blood of and the elimination of the bacteria in the bloodstream.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
DMSc, Aarhus University, The Molecular Biology and Diagnostics of Chlamydia trachomatis
Award Date: 27 Apr 1992
PhD, University of Aarhus, Synthesis of monoclonal antibodies by in vivo and in vitro stimulation and immunological analysis of Chlamydia trachomatis
Award Date: 27 Jan 1989
MD, University of Copenhagen
Award Date: 30 Jun 1983
Keywords
- Medicine
- Microbiology
- Chlamydia
- Klebsiella
- Immunology
- Sepsis
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Collaborations from the last five years
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Projects
- 6 Finished
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Elimination of microorganisms by the innate immune system - Obel Family Foundation - 34260
Birkelund, S. (PI)
01/09/2018 → 31/08/2022
Project: Research
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Gastrointestinal biomarkers
Stensballe, A. (Project Participant), Andersen, V. (Project Participant), Bennike, T. B. (Project Participant) & Birkelund, S. (Project Participant)
01/09/2014 → 31/08/2016
Project: Research
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Biomarkers in Osteoarthritis
Bennike, T. B. (Project Participant), Stensballe, A. (Project Participant) & Birkelund, S. (Project Participant)
01/09/2012 → 01/09/2015
Project: Research
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Interleukin-1 in the pathogenesis and treatment of inflammatory diseases
Carlsen, T. G. (Project Participant) & Birkelund, S. (Project Manager)
10/04/2012 → 01/12/2014
Project: Research
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Inflammatory Diseases - Analysis of the Underlying Biological Triggers
Carlsen, T. G. (Project Participant), Birkelund, S. (Project Participant), Bennike, T. B. (Project Participant) & Stensballe, A. (Project Participant)
01/12/2011 → 01/12/2014
Project: Research
Research output
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The role of opsonophagocytosis in killing of Klebsiella pneumoniae in human blood
Hymøller, C. M., Jensen, T. S., Rasmussen, P. V., Bech, D., Christiansen, G. & Birkelund, S., 2025, In: Current Research in Microbial Sciences. 9, 100449.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile20 Downloads (Pure) -
Differences in complement activation of serum-resistant and serum-sensitive Klebsiella pneumoniae isolates
Thomsen, M. E., Bennike, T. B., Christiansen, G., Emmersen, J., Laursen, N. S., Zarantonello, A., Andersen, G. R., Liu, L., Dueholm, M. K. D., Opstrup, K. V., Stensballe, A. & Birkelund, S., Jul 2025, In: Molecular Immunology. 183, p. 274-285 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
1 Citation (Scopus) -
Immunohistochemical Profiling of Interferon-Stimulated Genes in Histopathological Specimens: A Potential Screening Approach for Viral Infections
Thomsen, C., Birkelund, S. & Røge, R., Jun 2025, In: APMIS - Journal of Pathology, Microbiology and Immunology. 133, 6, e70034.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile1 Citation (Scopus)39 Downloads (Pure) -
Nanobodies raised against the cytotoxic α-synuclein oligomer are oligomer-specific and promote its cellular uptake
Nielsen, J., Pedersen, J. N., Kleijwegt, G., Nowak, J. S., Nami, F., Johansen, C., Sassetti, E., Berg, B. B., Lyngsø, N. M., Brøchner, B. V., Carlson, J. H., Simonsen, A., Olsen, W. P., Simonsen, B. W., Mikkelsen, J. H., Sereika-Bejder, V., Aarup Lauritsen, J., Merrild, K. F., Malle, M. G. & Valero, J. & 15 others, , Jun 2025, In: npj Biosensing. 2, 1, 23.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile21 Downloads (Pure) -
Selective Blockade of Two Aquaporin Channels, AQP3 and AQP9, Impairs Human Leukocyte Migration
Garra, S., Mejlstrup Hymøller, C., Di Molfetta, D., Zagaria, N., Gena, P., Cardone, R. A., Rützler, M., Birkelund, S. & Calamita, G., 11 Jun 2025, In: Cells. 14, 12, 880.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile1 Citation (Scopus)33 Downloads (Pure)
Datasets
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Additional file 1 of Proteomic analysis of synovial fluid from rheumatic arthritis and spondyloarthritis patients
Birkelund, S. (Creator), Bennike, T. B. (Creator), Kastaniegaard, K. (Creator), Lausen, M. (Creator), Poulsen, T. B. G. (Creator), Kragstrup, T. W. (Creator), Deleuran, B. W. (Creator), Christiansen, G. (Creator) & Stensballe, A. (Creator), Figshare, 6 Aug 2020
DOI: 10.6084/m9.figshare.12775188.v1, https://springernature.figshare.com/articles/Additional_file_1_of_Proteomic_analysis_of_synovial_fluid_from_rheumatic_arthritis_and_spondyloarthritis_patients/12775188/1 and one more link, https://springernature.figshare.com/articles/dataset/Additional_file_1_of_Proteomic_analysis_of_synovial_fluid_from_rheumatic_arthritis_and_spondyloarthritis_patients/12775188 (show fewer)
Dataset
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Complement deposition on Chlamydia trachomatis
Bennike, T. B. (Creator), Nielsen, M. L. (Creator), Thomsen, M. E. (Creator), Christiansen, G. (Creator), Karred, N. (Creator), Stensballe, A. (Creator) & Birkelund, S. (Creator), PRoteomics IDEntifications Database (PRIDE), 26 May 2020
https://www.ebi.ac.uk/pride/archive/projects/PXD019393
Dataset
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Proteomic analysis of synovial fluid from rheumatic arthritis and spondyloarthritis patients
Birkelund, S. (Creator), Bennike, T. B. (Creator), Kastaniegaard, K. (Creator), Lausen, M. (Creator), Poulsen, T. B. G. (Creator), Kragstrup, T. W. (Creator), Deleuran, B. W. (Creator), Christiansen, G. (Creator) & Stensballe, A. (Creator), Figshare, 2020
DOI: 10.6084/m9.figshare.c.5085102.v1, https://doi.org/10.6084%2Fm9.figshare.c.5085102.v1
Dataset
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Proteomic analysis of synovial fluid from rheumatic arthritis and spondyloarthritis patients
Birkelund, S. (Creator), Bennike, T. B. (Creator), Kastaniegaard, K. (Creator), Lausen, M. (Creator), Poulsen, T. B. G. (Creator), Kragstrup, T. W. (Creator), Deleuran, B. W. (Creator), Christiansen, G. (Creator) & Stensballe, A. (Creator), Figshare, 2020
DOI: 10.6084/m9.figshare.c.5085102, https://springernature.figshare.com/collections/Proteomic_analysis_of_synovial_fluid_from_rheumatic_arthritis_and_spondyloarthritis_patients/5085102
Dataset
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Additional file 4: Table S3. of Mass spectrometry analysis of adipose-derived stem cells reveals a significant effect of hypoxia on pathways regulating extracellular matrix
Pennisi, C. P. (Creator), Stensballe, A. (Creator), Birkelund, S. (Creator), Riis, S. (Creator), Emmersen, J. (Creator), Fink, T. (Creator) & Zachar, V. (Creator), Figshare, 15 Dec 2016
DOI: 10.6084/m9.figshare.c.3624224_d2.v1, https://doi.org/10.6084%2Fm9.figshare.c.3624224_d2.v1
Dataset
Press/Media
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Superbakterie på fremmarch i Europa: Livstruende for ældre
03/04/2025
1 item of Media coverage
Press/Media: Press / Media
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Superbakterie på fremmarch i Europa: Her er alt, du skal vide
19/02/2025 → 24/02/2025
8 items of Media coverage
Press/Media: Press / Media
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Læger efterlyser viden om alternativ behandling
17/08/2020
2 items of Media coverage
Press/Media: Press / Media
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Sexologi fylder meget lidt på lægeuddannelsen
24/01/2020
4 items of Media coverage
Press/Media: Press / Media