Projects per year
Personal profile
Research profile
With the initial research being focused on virology, the recent scientific interests span the fields of stem cells and regenerative medicine at large. The specific topics encompass the stem cells responses to hypoxia/normoxia and mechanical stimuli, biology of adipose-derived and limbal stem cells, and biomedical application of stem cells for tissue engineering and treating selected diseases.
Teaching profile
Teaching activities involve both the undergraduate and graduate levels. As a part of the bachelor curriculum, the main responsibility is to oversee the course on reproduction and facilitate the problem-based learning through the patient cases. At the master part, the main task is to coordinate the course on regenerative medicine and to supervise the student projects.
Administrative profile
The main administrative responsibility is to head the group of Regenerative Medicine. There are additional tasks related to the work in the committees constituted ad-hoc by the Faculty of Medicine.
PhD Supervision
Mentoring of the PhD students is carried out within the framework of the medical faculty-affiliated doctoral school.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Virology, PhD, Molecular properties of HIV, Slovak Academy of Sciences
Award Date: 11 Mar 1987
General Medicine, Doctor of Medicine, Comenius University
Award Date: 1 Aug 1980
Keywords
- Biomedicine
- Pluripotent stem cells
- Regenerative medicine
- Limbal stem cells
- Adipose-derived stem cells
- Stem cell biomarkers
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Collaborations from the last five years
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The use of electricity-stimulated stem cells for chronic wound
Peng, Q. (PI), Qian, Y. (Project Participant), Zachar, V. (Supervisor), Fink, T. (Project Participant), Porsborg, S. R. (Project Participant) & Xiao, X. (Supervisor)
01/11/2023 → 30/11/2027
Project: PhD Project
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PULSE: Precise understanding of vascular smooth muscle disease through advanced 3D-printed models
Pennisi, P. (PI), Zachar, V. (CoPI) & Gao, F. (Project Participant)
Fonden til Lægevidenskabens Fremme, Snedkermester Sophus Jacobsen og Hustru Astrid Jacobsens Fond
01/11/2023 → 31/10/2026
Project: Research
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Potency markers for Adipose-derived Stem Cells for treatment of Chronic Wounds
Ren, G. (PI), Porsborg, S. R. (Supervisor), Fink, T. (Supervisor), Peng, Q. (Project Participant) & Zachar, V. (Project Participant)
15/10/2018 → …
Project: Research
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Potency assays for wound healing
Porsborg, S. R. (PI), Ren, G. (Project Participant), Fink, T. (Project Participant), Peng, Q. (Project Participant) & Zachar, V. (Project Participant)
01/09/2018 → …
Project: Research
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Differentiation and engineering of smooth muscle
Emmersen, J. (Project Participant), Wang, F. (Project Participant), Zachar, V. (Project Participant) & Pennisi, P. (Project Participant)
01/01/2011 → …
Project: Research
Research output
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Assessment of Embedded Bioprinting for the Fabrication of Smooth Muscle Tissue Models
Gao, F., Zachar, V. & Pennisi, P., May 2025, p. 11.Research output: Contribution to conference without publisher/journal › Conference abstract for conference › Research › peer-review
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Comparative analysis of cryopreserved adipose stem cells expanded in hollow fiber bioreactor versus conventional tissue culture flasks
Ren, G., Sørensen, M. B., Porsborg, S. R., Fink, T., Zachar, V. & Peng, Q., 30 Dec 2024, In: Scientific Reports. 14, 1, 31853.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile13 Downloads (Pure) -
Effect of Postbiotics Derived from Lactobacillus rhamnosus PB01 (DSM 14870) on Sperm Quality: A Prospective In Vitro Study
Liu, S., Alipour, H., Zachar, V., Kesmodel, U. S. & Dardmeh, F., 6 Jun 2024, In: Nutrients. 16, 11, 1781.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile1 Citation (Scopus)28 Downloads (Pure) -
Hydrogel-elastomer interface engineering for cyclic mechanical stimulation of bioprinted 3D tissue constructs
Xuan, Z., Gurevich, L., Christiansen, J. D. C., Zachar, V. & Pennisi, P., Apr 2024, 17th Scandinavian Society for Biomaterials (ScSB) Meeting, Helsingør, Denmark, April 23-26, 2024: Soft Materials with Dynamic Properties. p. 46Research output: Contribution to book/anthology/report/conference proceeding › Conference abstract in proceeding › Research › peer-review
Open Access -
Immunophenotypical Characterization of Limbal Mesenchymal Stromal Cell Subsets during In Vitro Expansion
Aghazadeh, S., Peng, Q., Dardmeh, F., Hjortdal, J. Ø., Zachar, V. & Alipour, H., 9 Aug 2024, In: International Journal of Molecular Sciences . 25, 16, 8684.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile31 Downloads (Pure)
Datasets
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Maintaining RNA Integrity for Transcriptomic Profiling of Ex Vivo Cultured Limbal Epithelial Stem Cells after Fluorescence-Activated Cell Sorting (FACS)
Liu, L. (Creator), Nielsen, F. M. (Creator), Riis, S. E. (Creator), Emmersen, J. (Creator), Fink, T. (Creator), Hjortdal, J. Ø. (Creator), Bath, C. (Creator) & Zachar, V. (Creator), Figshare, 2017
DOI: 10.6084/m9.figshare.c.3952822, https://figshare.com/collections/Maintaining_RNA_Integrity_for_Transcriptomic_Profiling_of_Ex_Vivo_Cultured_Limbal_Epithelial_Stem_Cells_after_Fluorescence-Activated_Cell_Sorting_FACS_/3952822
Dataset
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Maintaining RNA Integrity for Transcriptomic Profiling of Ex Vivo Cultured Limbal Epithelial Stem Cells after Fluorescence-Activated Cell Sorting (FACS)
Liu, L. (Creator), Nielsen, F. M. (Creator), Riis, S. E. (Creator), Emmersen, J. (Creator), Fink, T. (Creator), Hjortdal, J. Ø. (Creator), Bath, C. (Creator) & Zachar, V. (Creator), Figshare, 2017
DOI: 10.6084/m9.figshare.c.3952822.v1, https://figshare.com/collections/Maintaining_RNA_Integrity_for_Transcriptomic_Profiling_of_Ex_Vivo_Cultured_Limbal_Epithelial_Stem_Cells_after_Fluorescence-Activated_Cell_Sorting_FACS_/3952822/1
Dataset
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Additional file 1: of Maintaining RNA Integrity for Transcriptomic Profiling of Ex Vivo Cultured Limbal Epithelial Stem Cells after Fluorescence-Activated Cell Sorting (FACS)
Liu, L. (Creator), Nielsen, F. M. (Creator), Riis, S. E. (Creator), Emmersen, J. (Creator), Fink, T. (Creator), Hjortdal, J. Ø. (Creator), Bath, C. (Creator) & Zachar, V. (Creator), Figshare, 2017
DOI: 10.6084/m9.figshare.5696704.v1, https://doi.org/10.6084%2Fm9.figshare.5696704.v1
Dataset
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Additional file 3: Table S2. of Mass spectrometry analysis of adipose-derived stem cells reveals a significant effect of hypoxia on pathways regulating extracellular matrix
Riis, S. (Creator), Emmersen, J. (Creator), Stensballe, A. (Creator), Birkelund, S. (Creator), Zachar, V. (Creator), Fink, T. (Creator) & Pennisi, C. P. (Creator), Figshare, 15 Dec 2016
DOI: 10.6084/m9.figshare.c.3624224_d4.v1, https://doi.org/10.6084%2Fm9.figshare.c.3624224_d4.v1
Dataset
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Additional file 2: Table S1. of Mass spectrometry analysis of adipose-derived stem cells reveals a significant effect of hypoxia on pathways regulating extracellular matrix
Birkelund, S. (Creator), Zachar, V. (Creator), Riis, S. (Creator), Emmersen, J. (Creator), Pennisi, C. P. (Creator), Stensballe, A. (Creator) & Fink, T. (Creator), Figshare, 15 Dec 2016
DOI: 10.6084/m9.figshare.c.3624224_d1.v1, https://doi.org/10.6084%2Fm9.figshare.c.3624224_d1.v1
Dataset
Press/Media
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Kommision slår fast: Sensationel stamcelleforskning var fusk
03/04/2014
1 item of Media coverage
Press/Media: Press / Media
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