Research output per year
Research output per year
Project Details
Description
The project revolves around STING-induced activation of dendritic cells and macrophages within the tumor microenvironment, and how this may aid other immunotherapeutic strategies, including check-point blockade therapy.
| Status | Active |
|---|---|
| Effective start/end date | 01/05/2018 → … |
Collaborative partners
- Aarhus University
Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
Research output
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Cholesterol-binding motifs in STING that control endoplasmic reticulum retention mediate anti-tumoral activity of cholesterol-lowering compounds
Zhang, B.-C., Laursen, M. F., Hu, L., Hazrati, H., Narita, R., Jensen, L. S., Hansen, A. S., Huang, J., Zhang, Y., Ding, X., Muyesier, M., Nilsson, E., Banasik, A., Zeiler, C., Mogensen, T. H., Etzerodt, A., Agger, R., Johannsen, M., Kofod-Olsen*, E. & Paludan*, S. R. & 1 others, , 29 Mar 2024, In: Nature Communications. 15, 1 , 2760. *contributed equally.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile1 Citation (Scopus)13 Downloads (Pure) -
Cholesterol-Inhibition Slow Development of Cancer in CT26 and MC38 Cancer Models
Jensen, T. S., Laursen, M. F., Pedersen, N. M. M., Smodek, A., Jakobsen, M. R. & Kofod-Olsen, E., 2024.Research output: Contribution to conference without publisher/journal › Conference abstract for conference › Research › peer-review
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CD11c-targeted delivery of DNA to dendritic cells leads to cGAS- and STING-dependent maturation
Laursen, M. F., Christensen, E., Degn, L. L. T., Jønsson, K., Jakobsen, M. R., Agger, R. & Kofod-Olsen, E., 2018, In: Journal of Immunotherapy. 41, 1, p. 9-18 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
11 Citations (Scopus)
Press/Media
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Regulering af kolesterolniveauer kan være nøglen til bedre kræftbehandling
30/04/2024
1 item of Media coverage
Press/Media: Press / Media