Techno-economic and life-cycle analysis of single-use technology in biomanufacturing

Single-use technology is evaluated for their potential in the seed train and whole upstream as well as downstream processing in bio-based applications. Own research on using single-use bioreactors in microbial processes is complemented with available data to investigate the potential benefits. Since sterilization and cleaning differ vastly between single-use and conventional steel-based euqipment, it is interesting to observe, under which conditions single-use equipment is a good alternative despite the disposable nature. Our research also aims for the support of open access platforms, in which individual users can get access to data to drive their own decsion for or against single-use equipment including sustainability aspects.