Project Details


Knee osteoarthritis is a frequently occurring joint disease that causes pain, joint
deformity, reduced quality-of-life and walking disability. At advanced stages, joint
replacement, so-called total knee arthroplasty (TKA), may be necessary. Although
TKA is generally considered successful, 16-30% of patients are dissatisfied. There
are multiple reasons for this, but some of the most frequent reasons for revision
are instability and joint stiffness. A possible explanation for this is that the implant
geometry is not optimized to ensure joint stability in the individual patient. This we
wish to change in this project by developing a new patient-specific implant
optimized to ensure knee stability and implement it using intraoperative sensors to
ensure an optimized result. This methodology we will compare against traditional
TKA to document that we obtain better post-operative knee stability.
Effective start/end date01/07/202030/06/2023

Collaborative partners

  • Department of Materials and Production, Aalborg University (lead)
  • Radboud University Medical Center
  • Orthosensor
  • Anybody Technology A/S


  • Independent Research Fund Denmark: DKK2,879,532.00


  • Total knee arthroplasty
  • Patient-specific implant,
  • Soft tissue balancing
  • Musculoskeletal modeling


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