A gain-of-function mutation in the ITPR1 gating domain causes male infertility in mice

Bo Sun, Mingke Ni, Shanshan Tian, Wenting Guo, Shitian Cai, Mads T Sondergaard, Yongxiang Chen, Yongxin Mu, John P Estillore, Ruiwu Wang, Ju Chen, Michael T Overgaard, Michael Fill, Josefina Ramos-Franco, Mette Nyegaard, Sui Rong Wayne Chen

Research output: Contribution to journalJournal articleResearchpeer-review

Original languageEnglish
JournalJournal of cellular physiology
Volume237
Issue number8
Pages (from-to)3305-3316
ISSN0021-9541
DOIs
Publication statusPublished - Aug 2022

Bibliographical note

© 2022 Wiley Periodicals LLC.

Keywords

  • acrosome
  • azoospermia
  • gain-of-function mutation
  • inositol 1,4,5-trisphosphate receptor
  • intracellular Ca release
  • male infertility

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