A global perspective on the treatment and maintenance of mature skin using gentle cleansers and moisturizers

Joachim W. Fluhr, Andrew F. Alexis, Anneke Andriessen*, Olga L. Ferero Barrios, Peter Bjerring, Peter Foley, Michael H. Gold, Hashim Kaderbhai, Chengfeng Zhang

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

Xerosis is highly prevalent in the population aged over 50 years and substantially impacts quality of life due to the associated stigma, related pruritus, and potential sequelae. We propose that the term mature xerosis be used for subjects over 50 who suffer from age-related xerosis and replace senile xerosis to describe the phenomenon. The etiology of xerosis depends on genetic and environmental factors that affect stratum corneum hydration and skin barrier function. Skincare to restore barrier function is essential in xerosis treatment and is relevant for maintaining and preventing its progression. Many moisturizers and cleansers are available for xerosis; however, they are underutilized by patients with mature xerosis. A panel of eight global dermatologists reviewed the unique aspects of xerosis in mature skin and discussed the specific needs, relevance, and considerations for skincare selection to prevent, treat, and maintain skin with mature xerosis. The panel selected five statements based on evidence from a literature review and the panel's clinical experience to provide clinical considerations and recommendations for dermatologists and other healthcare providers treating patients with mature xerosis. Increased recognition of the burden of xerosis in mature skin is warranted. Gentle cleansers and barrier-restoring ceramide-containing moisturizers are essential to xerosis management, reducing signs and symptoms of xerosis, including associated pruritus.

Original languageEnglish
JournalInternational Journal of Dermatology
Volume63
Issue number12
Pages (from-to)1676-1684
Number of pages9
ISSN0011-9059
DOIs
Publication statusPublished - Dec 2024

Bibliographical note

© 2024 The Author(s). International Journal of Dermatology published by Wiley Periodicals LLC on behalf of the International Society of Dermatology.

Keywords

  • ceramide
  • mature skin
  • moisturizers
  • skincare
  • xerosis

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