Photovoltaic (PV) water pumping systems are becoming popular these days. In PV water pumping, the role of the converter is most important, especially in the renewable energy-based PV systems case. This study focuses on one such application. In this proposed work, direct current (DC) based intermediate DC-DC power converter, i.e., a modified LUO (M-LUO) converter is used to extricate the availability of power in the high range from the PV array. The M-LUO converter is controlled efficiently by utilizing the Grey Wolf Optimizer (GWO)-based maximum power point tracking algorithm, which aids the smooth starting of a brushless DC (BLDC) motor. The voltage source inverter’s (VSI) fundamental switching frequency is achieved in the BLDC motor by electronic commutation. Hence, the occurrence of VSI losses due to a high switching frequency is eliminated. The GWO optimized algorithm is compared with the perturb and observe (P&O) and fuzzy logic based maximum power point tracking (MPPT) algorithms. However, by sensing the position of the rotor and comparing the reference speed with the actual speed, the speed of the BLDC motor is controlled by the proportional-integral (PI) controller. The recent advancement in motor drives based on distributed sources generates more demand for highly efficient permanent magnet (PM) motor drives, and this was the beginning of interest in BLDC motors. Thus, in this paper, the design of a high-gain boost converter optimized by a GWO algorithm is proposed to drive the BLDC-based pumping motor. The proposed work is simulated in MATLAB-SIMULINK, and the experimental results are verified using the dsPIC30F2010 controller.