A Neutralizing Monoclonal Antibody for Hospitalized Patients with Covid-19

ACTIV-3/TICO LY-CoV555 Study Group, Writing Commitee, Jens D Lundgren (Member of study group), Birgit Grund (Member of study group), Christina E Barkauskas (Member of study group), Thomas L Holland (Member of study group), Robert L Gottlieb (Member of study group), Uriel Sandkovsky (Member of study group), Samuel M Brown (Member of study group), Kirk U Knowlton (Member of study group), Wesley H Self (Member of study group), D Clark Files (Member of study group), Mamta K Jain (Member of study group), Thomas Benfield (Member of study group), Michael E Bowdish (Member of study group), Bradley G Leshnower (Member of study group), Jason V Baker (Member of study group), Jens-Ulrik Jensen (Member of study group), Edward M Gardner (Member of study group), Adit A Ginde (Member of study group)Estelle S Harris, Isik S Johansen, Norman Markowitz, Michael A Matthay, Lars Østergaard, Christina C Chang, Victoria J Davey, Anna Goodman, Elizabeth S Higgs, Daniel D Murray, Thomas A Murray, Roger Paredes, Mahesh K B Parmar, Andrew N Phillips, Cavan Reilly, Shweta Sharma, Robin L Dewar, Marc Teitelbaum, Deborah Wentworth, Huyen Cao, Paul Klekotka, Abdel G Babiker, Annetine C Gelijns, Virginia L Kan, Mark N Polizzotto, B Taylor Thompson, H Clifford Lane, James D Neaton, TICO Study Group, Henrik Nielsen

Research output: Contribution to journalJournal articlepeer-review

58 Citations (Scopus)
Original languageEnglish
JournalThe New England Journal of Medicine
Issue number10
Pages (from-to)905-914
Number of pages10
Publication statusPublished - 11 Mar 2021


  • Adenosine Monophosphate/analogs & derivatives
  • Adult
  • Aged
  • Alanine/analogs & derivatives
  • Antibodies, Monoclonal, Humanized/adverse effects
  • Antibodies, Neutralizing/adverse effects
  • Antiviral Agents/adverse effects
  • COVID-19/drug therapy
  • Double-Blind Method
  • Drug Therapy, Combination
  • Female
  • Glucocorticoids/therapeutic use
  • Hospitalization
  • Humans
  • Intention to Treat Analysis
  • Male
  • Middle Aged
  • Treatment Failure


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