A Neutralizing Monoclonal Antibody for Hospitalized Patients with Covid-19

Jens D Lundgren (Member of study group), Birgit Grund (Member of study group), Christina E Barkauskas (Member of study group), Thomas L Holland (Member of study group), Robert L Gottlieb (Member of study group), Uriel Sandkovsky (Member of study group), Samuel M Brown (Member of study group), Kirk U Knowlton (Member of study group), Wesley H Self (Member of study group), D Clark Files (Member of study group), Mamta K Jain (Member of study group), Thomas Benfield (Member of study group), Michael E Bowdish (Member of study group), Bradley G Leshnower (Member of study group), Jason V Baker (Member of study group), Jens-Ulrik Jensen (Member of study group), Edward M Gardner (Member of study group), Adit A Ginde (Member of study group), Estelle S Harris (Member of study group), Isik S Johansen (Member of study group)Norman Markowitz (Member of study group), Michael A Matthay (Member of study group), Lars Østergaard (Member of study group), Christina C Chang (Member of study group), Victoria J Davey (Member of study group), Anna Goodman (Member of study group), Elizabeth S Higgs (Member of study group), Daniel D Murray (Member of study group), Thomas A Murray (Member of study group), Roger Paredes (Member of study group), Mahesh K B Parmar (Member of study group), Andrew N Phillips (Member of study group), Cavan Reilly (Member of study group), Shweta Sharma (Member of study group), Robin L Dewar (Member of study group), Marc Teitelbaum (Member of study group), Deborah Wentworth (Member of study group), Huyen Cao (Member of study group), Paul Klekotka (Member of study group), Abdel G Babiker (Member of study group), Annetine C Gelijns (Member of study group), Virginia L Kan (Member of study group), Mark N Polizzotto (Member of study group), B Taylor Thompson (Member of study group), H Clifford Lane (Member of study group), James D Neaton (Member of study group), TICO Study Group, Henrik Nielsen (Member of study group), ACTIV-3/TICO LY-CoV555 Study Group, Writing Commitee

Research output: Contribution to journalJournal articleResearchpeer-review

196 Citations (Scopus)
Original languageEnglish
JournalThe New England Journal of Medicine
Volume384
Issue number10
Pages (from-to)905-914
Number of pages10
ISSN0028-4793
DOIs
Publication statusPublished - 11 Mar 2021

Keywords

  • Adenosine Monophosphate/analogs & derivatives
  • Adult
  • Aged
  • Alanine/analogs & derivatives
  • Antibodies, Monoclonal, Humanized/adverse effects
  • Antibodies, Neutralizing/adverse effects
  • Antiviral Agents/adverse effects
  • COVID-19/drug therapy
  • Double-Blind Method
  • Drug Therapy, Combination
  • Female
  • Glucocorticoids/therapeutic use
  • Hospitalization
  • Humans
  • Intention to Treat Analysis
  • Male
  • Middle Aged
  • Treatment Failure

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