An Untargeted Metabolomics Survey from a Perturbation Model of Nitrogen Transformation in a Tropical Wastewater Community

Rasmus Hansen Kirkegaard; Anisa Angel Cokro; Shivshankar Umashankar; Victor Nesati; Sanjay Swarup; Per Halkjær Nielsen; Rohan Williams; Stefan Wuertz

An Untargeted Metabolomics Survey from a Perturbation Model of Nitrogen Transformation in a Tropical Wastewater Community

Rasmus Hansen Kirkegaard, Anisa Angel Cokro, Shivshankar Umashankar, Victor Nesati, Sanjay Swarup, Per Halkjær Nielsen, Rohan Williams, Stefan Wuertz

Research output: Contribution to conference without publisher/journal › Conference abstract for conference › Research › peer-review

Abstract

In order to understand metabolic changes occurring during nitrogen transformation in a complex wastewater community, we conducted a metabolome time series study on a volume of freshly sourced, anoxic activated sludge, studying metabolic changes associated with the transition from anoxic to aerobic states. We develop analytic procedures for identifying reliable mass features that are modulated over the time, and are significantly correlated with shifts in physiochemical states. Our methods are widely applicable, and point towards to development of an eco-systems biology approach suitable for the targeted investigation of bioprocesses associated with engineered ecosystems.

Original language	English
Publication date	2013
Publication status	Published - 2013
Event	Microbial Ecology and Water Engineering 2013 - Ann Arbor, Michigan, United States Duration: 7 Jul 2013 → 10 Jul 2013 Conference number: 5

Conference

Conference	Microbial Ecology and Water Engineering 2013
Number	5
Country/Territory	United States
City	Ann Arbor, Michigan
Period	07/07/2013 → 10/07/2013

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title = "An Untargeted Metabolomics Survey from a Perturbation Model of Nitrogen Transformation in a Tropical Wastewater Community",

abstract = "In order to understand metabolic changes occurring during nitrogen transformation in a complex wastewater community, we conducted a metabolome time series study on a volume of freshly sourced, anoxic activated sludge, studying metabolic changes associated with the transition from anoxic to aerobic states. We develop analytic procedures for identifying reliable mass features that are modulated over the time, and are significantly correlated with shifts in physiochemical states. Our methods are widely applicable, and point towards to development of an eco-systems biology approach suitable for the targeted investigation of bioprocesses associated with engineered ecosystems.",

author = "Kirkegaard, {Rasmus Hansen} and {Angel Cokro}, Anisa and Shivshankar Umashankar and Victor Nesati and Sanjay Swarup and Nielsen, {Per Halkj{\ae}r} and Rohan Williams and Stefan Wuertz",

year = "2013",

language = "English",

note = "Microbial Ecology and Water Engineering 2013, MEWE2013 ; Conference date: 07-07-2013 Through 10-07-2013",

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An Untargeted Metabolomics Survey from a Perturbation Model of Nitrogen Transformation in a Tropical Wastewater Community. / Kirkegaard, Rasmus Hansen; Angel Cokro, Anisa; Umashankar, Shivshankar et al.
2013. Abstract from Microbial Ecology and Water Engineering 2013, Ann Arbor, Michigan, United States.

Research output: Contribution to conference without publisher/journal › Conference abstract for conference › Research › peer-review

TY - ABST

T1 - An Untargeted Metabolomics Survey from a Perturbation Model of Nitrogen Transformation in a Tropical Wastewater Community

AU - Kirkegaard, Rasmus Hansen

AU - Angel Cokro, Anisa

AU - Umashankar, Shivshankar

AU - Nesati, Victor

AU - Swarup, Sanjay

AU - Nielsen, Per Halkjær

AU - Williams, Rohan

AU - Wuertz, Stefan

N1 - Conference code: 5

PY - 2013

Y1 - 2013

N2 - In order to understand metabolic changes occurring during nitrogen transformation in a complex wastewater community, we conducted a metabolome time series study on a volume of freshly sourced, anoxic activated sludge, studying metabolic changes associated with the transition from anoxic to aerobic states. We develop analytic procedures for identifying reliable mass features that are modulated over the time, and are significantly correlated with shifts in physiochemical states. Our methods are widely applicable, and point towards to development of an eco-systems biology approach suitable for the targeted investigation of bioprocesses associated with engineered ecosystems.

AB - In order to understand metabolic changes occurring during nitrogen transformation in a complex wastewater community, we conducted a metabolome time series study on a volume of freshly sourced, anoxic activated sludge, studying metabolic changes associated with the transition from anoxic to aerobic states. We develop analytic procedures for identifying reliable mass features that are modulated over the time, and are significantly correlated with shifts in physiochemical states. Our methods are widely applicable, and point towards to development of an eco-systems biology approach suitable for the targeted investigation of bioprocesses associated with engineered ecosystems.

M3 - Conference abstract for conference

T2 - Microbial Ecology and Water Engineering 2013

Y2 - 7 July 2013 through 10 July 2013

ER -