Anti H-Y immunity in secondary recurrent miscarriage—immunogenetic and immunologic evidence

H S Nielsen, R Steffensen, A G van Halteren, E Spierings, D Miklos, E Goulmy, F Claas, O B Christiansen

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Abstract

The birth of a boy is significantly more common than a girl prior to secondary recurrent miscarriage (SRM) and is associated with a poorer chance of a subsequent live birth. Children born after SRM are more likely to be girls. High-titer antisera specific for male antigens (H-Y) have been shown to arrest development of male bovine embryos efficiently. We consequently questioned the role of H-Y antibodies in women with SRM.
Original languageEnglish
JournalJournal of Reproductive Immunology
Volume90
Pages (from-to)142-3
Number of pages2
ISSN0165-0378
DOIs
Publication statusPublished - 2011
Externally publishedYes

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