Assessment of colorectal length using the electromagnetic capsule tracking system: a comparative validation study in healthy subjects

Esben Bolvig Mark, Jakob Lykke Poulsen, Anne-Mette Haase, J B Frøkjaer, V. Schlageter, S M Scott, K Krogh, A M Drewes

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

AIM: We aimed to determine colorectal length with the 3D-Transit system by describing a 'centerline' of capsule movement and compare it to known anatomy, as determined by magnetic resonance imaging (MRI). Further, we aimed to test the day-to-day variation of colorectal length assessed with the system.

METHOD: The 3D-Transit system consists of electromagnetic capsules that can be tracked as they traverse the gastrointestinal tract. 25 healthy subjects were examined with both 3D-Transit and MRI. Another 21 healthy subjects were examined with 3D-Transit on two consecutive days.

RESULTS: Computation of colorectal length from capsule passage was possible in 60 of the 67 3D-Transit recordings. Length of the colorectum measured with MRI and 3D-Transit was respectively 95 cm (75-153 cm) and 99 cm (77-147 cm), P = 0.15. Coefficient of variation (CV) between MRI and 3D-Transit was 7.8%. Apart from the cecum / ascending colon being 26% (P = 0.002) shorter on MRI, there were no other differences in total or segmental colorectal lengths between methods (all P > 0.05). Length of the colorectum measured with 3D-Transit on two consecutive days was 102 cm (73-119 cm) and 103 cm (75-123 cm), P = 0.67. CV between days was 7.3%.

CONCLUSIONS: The 3D-Transit system allows accurate and reliable determination of colorectal length compared to MRI derived colorectal length and between days. Antegrade or retrograde capsule movement relative to this centerline, as well as the length and speed of movements may be determined by future studies to allow better classification and treatment in patients with dysmotility. This article is protected by copyright. All rights reserved.

Original languageEnglish
JournalColorectal Disease
Volume19
Issue number9
Pages (from-to)O350-O357
ISSN1462-8910
DOIs
Publication statusPublished - 2017

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Validation Studies
Electromagnetic Phenomena
Capsules
Healthy Volunteers
Magnetic Resonance Imaging
Ascending Colon
Cecum
Gastrointestinal Tract
Anatomy

Keywords

  • Journal Article

Cite this

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title = "Assessment of colorectal length using the electromagnetic capsule tracking system: a comparative validation study in healthy subjects",
abstract = "AIM: We aimed to determine colorectal length with the 3D-Transit system by describing a 'centerline' of capsule movement and compare it to known anatomy, as determined by magnetic resonance imaging (MRI). Further, we aimed to test the day-to-day variation of colorectal length assessed with the system.METHOD: The 3D-Transit system consists of electromagnetic capsules that can be tracked as they traverse the gastrointestinal tract. 25 healthy subjects were examined with both 3D-Transit and MRI. Another 21 healthy subjects were examined with 3D-Transit on two consecutive days.RESULTS: Computation of colorectal length from capsule passage was possible in 60 of the 67 3D-Transit recordings. Length of the colorectum measured with MRI and 3D-Transit was respectively 95 cm (75-153 cm) and 99 cm (77-147 cm), P = 0.15. Coefficient of variation (CV) between MRI and 3D-Transit was 7.8{\%}. Apart from the cecum / ascending colon being 26{\%} (P = 0.002) shorter on MRI, there were no other differences in total or segmental colorectal lengths between methods (all P > 0.05). Length of the colorectum measured with 3D-Transit on two consecutive days was 102 cm (73-119 cm) and 103 cm (75-123 cm), P = 0.67. CV between days was 7.3{\%}.CONCLUSIONS: The 3D-Transit system allows accurate and reliable determination of colorectal length compared to MRI derived colorectal length and between days. Antegrade or retrograde capsule movement relative to this centerline, as well as the length and speed of movements may be determined by future studies to allow better classification and treatment in patients with dysmotility. This article is protected by copyright. All rights reserved.",
keywords = "Journal Article",
author = "Mark, {Esben Bolvig} and Poulsen, {Jakob Lykke} and Anne-Mette Haase and Fr{\o}kjaer, {J B} and V. Schlageter and Scott, {S M} and K Krogh and Drewes, {A M}",
note = "This article is protected by copyright. All rights reserved.",
year = "2017",
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language = "English",
volume = "19",
pages = "O350--O357",
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Assessment of colorectal length using the electromagnetic capsule tracking system : a comparative validation study in healthy subjects. / Mark, Esben Bolvig; Poulsen, Jakob Lykke; Haase, Anne-Mette; Frøkjaer, J B; Schlageter, V.; Scott, S M; Krogh, K; Drewes, A M.

In: Colorectal Disease, Vol. 19, No. 9, 2017, p. O350-O357.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - Assessment of colorectal length using the electromagnetic capsule tracking system

T2 - a comparative validation study in healthy subjects

AU - Mark, Esben Bolvig

AU - Poulsen, Jakob Lykke

AU - Haase, Anne-Mette

AU - Frøkjaer, J B

AU - Schlageter, V.

AU - Scott, S M

AU - Krogh, K

AU - Drewes, A M

N1 - This article is protected by copyright. All rights reserved.

PY - 2017

Y1 - 2017

N2 - AIM: We aimed to determine colorectal length with the 3D-Transit system by describing a 'centerline' of capsule movement and compare it to known anatomy, as determined by magnetic resonance imaging (MRI). Further, we aimed to test the day-to-day variation of colorectal length assessed with the system.METHOD: The 3D-Transit system consists of electromagnetic capsules that can be tracked as they traverse the gastrointestinal tract. 25 healthy subjects were examined with both 3D-Transit and MRI. Another 21 healthy subjects were examined with 3D-Transit on two consecutive days.RESULTS: Computation of colorectal length from capsule passage was possible in 60 of the 67 3D-Transit recordings. Length of the colorectum measured with MRI and 3D-Transit was respectively 95 cm (75-153 cm) and 99 cm (77-147 cm), P = 0.15. Coefficient of variation (CV) between MRI and 3D-Transit was 7.8%. Apart from the cecum / ascending colon being 26% (P = 0.002) shorter on MRI, there were no other differences in total or segmental colorectal lengths between methods (all P > 0.05). Length of the colorectum measured with 3D-Transit on two consecutive days was 102 cm (73-119 cm) and 103 cm (75-123 cm), P = 0.67. CV between days was 7.3%.CONCLUSIONS: The 3D-Transit system allows accurate and reliable determination of colorectal length compared to MRI derived colorectal length and between days. Antegrade or retrograde capsule movement relative to this centerline, as well as the length and speed of movements may be determined by future studies to allow better classification and treatment in patients with dysmotility. This article is protected by copyright. All rights reserved.

AB - AIM: We aimed to determine colorectal length with the 3D-Transit system by describing a 'centerline' of capsule movement and compare it to known anatomy, as determined by magnetic resonance imaging (MRI). Further, we aimed to test the day-to-day variation of colorectal length assessed with the system.METHOD: The 3D-Transit system consists of electromagnetic capsules that can be tracked as they traverse the gastrointestinal tract. 25 healthy subjects were examined with both 3D-Transit and MRI. Another 21 healthy subjects were examined with 3D-Transit on two consecutive days.RESULTS: Computation of colorectal length from capsule passage was possible in 60 of the 67 3D-Transit recordings. Length of the colorectum measured with MRI and 3D-Transit was respectively 95 cm (75-153 cm) and 99 cm (77-147 cm), P = 0.15. Coefficient of variation (CV) between MRI and 3D-Transit was 7.8%. Apart from the cecum / ascending colon being 26% (P = 0.002) shorter on MRI, there were no other differences in total or segmental colorectal lengths between methods (all P > 0.05). Length of the colorectum measured with 3D-Transit on two consecutive days was 102 cm (73-119 cm) and 103 cm (75-123 cm), P = 0.67. CV between days was 7.3%.CONCLUSIONS: The 3D-Transit system allows accurate and reliable determination of colorectal length compared to MRI derived colorectal length and between days. Antegrade or retrograde capsule movement relative to this centerline, as well as the length and speed of movements may be determined by future studies to allow better classification and treatment in patients with dysmotility. This article is protected by copyright. All rights reserved.

KW - Journal Article

U2 - 10.1111/codi.13810

DO - 10.1111/codi.13810

M3 - Journal article

VL - 19

SP - O350-O357

JO - Colorectal Disease

JF - Colorectal Disease

SN - 1462-8910

IS - 9

ER -