Association between chronic pain and the sperm motion characteristics

Fereshteh Dardmeh, Hiva Alipour, Hans Ingolf Nielsen, Sten Rasmussen, Jasmine Tannaz Yousefi, Nadja Ditlevsen, Hanim Abdalla Abdel Karim Taha Yasin, Edon Morina, René Kleist Duus, Parisa Gazerani

Research output: Contribution to book/anthology/report/conference proceedingConference abstract in proceedingResearch

Abstract

Sex hormones play an important role in pain in many chronic pain conditions. Relationship between chronic pain and sperm quality has not been investigated thoroughly and may provide an insight to better understanding, management and treatment of cases where chronic pain and male sub-fertility co-exist.
Neat (fresh semen) and processed sperm from 15 males with orthopedic chronic pain (CP) were assessed and compared with 15 healthy age matched controls. Sperm analysis was performed using the SCA computer-aided sperm analyzer.
There was no significant difference in any parameters of the neat semen between the pain and control group. However the percentage of non-progressive motile spermatozoa (type B) was significantly higher in the pain group (27.96) compared to the control group (15.96Straight line trajectories including linearity, straightness, wobble and beat cross frequency were also significantly higher in the processed sample of the CP group.
This study demonstrated that chronic pain does not affect the sperm morphology, total concentration and motility based on conventional analysis but has significant influence at the level of sperm motion kinetics which could prove to be clinically valuable, prognostic indicators of successful fertilization. Maturation of sperm motility occurs during their transit through the epididymis and vas deferens regulated by androgens. As male gonadal hormones have an inhibitory, adaptive effect on the behavioral and neuronal responses to repeated nociceptive stimulation, it can be speculated that the observed difference in sperm kinematic parameters could be related to the alterations in serum sex hormone levels emanating from the chronic pain. Further studies are required to explain the possible mechanism of action of chronic pain on male fertility.
Original languageEnglish
Title of host publicationOfficial Program : SASP Annual Meeting 2015, Scandinavian Association for the Study of Pain, 13-14 April 2015, Stockholm, Sweden
Number of pages1
PublisherScandinavian Association for the study of Pain
Publication date2015
Publication statusPublished - 2015
EventAnnual meeting of the Scandinavian Association for the Study of Pain, SASP 2015 - Stockholm, Sweden
Duration: 13 Apr 201514 Apr 2015

Conference

ConferenceAnnual meeting of the Scandinavian Association for the Study of Pain, SASP 2015
CountrySweden
CityStockholm
Period13/04/201514/04/2015

Fingerprint

Chronic Pain
Spermatozoa
Gonadal Steroid Hormones
Semen
Pain
Gonadal Hormones
Control Groups
Vas Deferens
Sperm Motility
Epididymis
Male Infertility
Case Management
Biomechanical Phenomena
Fertilization
Androgens
Orthopedics
Fertility
Serum

Cite this

Dardmeh, F., Alipour, H., Nielsen, H. I., Rasmussen, S., Yousefi, J. T., Ditlevsen, N., ... Gazerani, P. (2015). Association between chronic pain and the sperm motion characteristics. In Official Program : SASP Annual Meeting 2015, Scandinavian Association for the Study of Pain, 13-14 April 2015, Stockholm, Sweden Scandinavian Association for the study of Pain.
Dardmeh, Fereshteh ; Alipour, Hiva ; Nielsen, Hans Ingolf ; Rasmussen, Sten ; Yousefi, Jasmine Tannaz ; Ditlevsen, Nadja ; Yasin, Hanim Abdalla Abdel Karim Taha ; Morina, Edon ; Duus, René Kleist ; Gazerani, Parisa. / Association between chronic pain and the sperm motion characteristics. Official Program : SASP Annual Meeting 2015, Scandinavian Association for the Study of Pain, 13-14 April 2015, Stockholm, Sweden. Scandinavian Association for the study of Pain, 2015.
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abstract = "Sex hormones play an important role in pain in many chronic pain conditions. Relationship between chronic pain and sperm quality has not been investigated thoroughly and may provide an insight to better understanding, management and treatment of cases where chronic pain and male sub-fertility co-exist.Neat (fresh semen) and processed sperm from 15 males with orthopedic chronic pain (CP) were assessed and compared with 15 healthy age matched controls. Sperm analysis was performed using the SCA computer-aided sperm analyzer. There was no significant difference in any parameters of the neat semen between the pain and control group. However the percentage of non-progressive motile spermatozoa (type B) was significantly higher in the pain group (27.96) compared to the control group (15.96Straight line trajectories including linearity, straightness, wobble and beat cross frequency were also significantly higher in the processed sample of the CP group. This study demonstrated that chronic pain does not affect the sperm morphology, total concentration and motility based on conventional analysis but has significant influence at the level of sperm motion kinetics which could prove to be clinically valuable, prognostic indicators of successful fertilization. Maturation of sperm motility occurs during their transit through the epididymis and vas deferens regulated by androgens. As male gonadal hormones have an inhibitory, adaptive effect on the behavioral and neuronal responses to repeated nociceptive stimulation, it can be speculated that the observed difference in sperm kinematic parameters could be related to the alterations in serum sex hormone levels emanating from the chronic pain. Further studies are required to explain the possible mechanism of action of chronic pain on male fertility.",
author = "Fereshteh Dardmeh and Hiva Alipour and Nielsen, {Hans Ingolf} and Sten Rasmussen and Yousefi, {Jasmine Tannaz} and Nadja Ditlevsen and Yasin, {Hanim Abdalla Abdel Karim Taha} and Edon Morina and Duus, {Ren{\'e} Kleist} and Parisa Gazerani",
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Dardmeh, F, Alipour, H, Nielsen, HI, Rasmussen, S, Yousefi, JT, Ditlevsen, N, Yasin, HAAKT, Morina, E, Duus, RK & Gazerani, P 2015, Association between chronic pain and the sperm motion characteristics. in Official Program : SASP Annual Meeting 2015, Scandinavian Association for the Study of Pain, 13-14 April 2015, Stockholm, Sweden. Scandinavian Association for the study of Pain, Annual meeting of the Scandinavian Association for the Study of Pain, SASP 2015, Stockholm, Sweden, 13/04/2015.

Association between chronic pain and the sperm motion characteristics. / Dardmeh, Fereshteh; Alipour, Hiva; Nielsen, Hans Ingolf; Rasmussen, Sten; Yousefi, Jasmine Tannaz; Ditlevsen, Nadja; Yasin, Hanim Abdalla Abdel Karim Taha; Morina, Edon; Duus, René Kleist; Gazerani, Parisa.

Official Program : SASP Annual Meeting 2015, Scandinavian Association for the Study of Pain, 13-14 April 2015, Stockholm, Sweden. Scandinavian Association for the study of Pain, 2015.

Research output: Contribution to book/anthology/report/conference proceedingConference abstract in proceedingResearch

TY - ABST

T1 - Association between chronic pain and the sperm motion characteristics

AU - Dardmeh, Fereshteh

AU - Alipour, Hiva

AU - Nielsen, Hans Ingolf

AU - Rasmussen, Sten

AU - Yousefi, Jasmine Tannaz

AU - Ditlevsen, Nadja

AU - Yasin, Hanim Abdalla Abdel Karim Taha

AU - Morina, Edon

AU - Duus, René Kleist

AU - Gazerani, Parisa

PY - 2015

Y1 - 2015

N2 - Sex hormones play an important role in pain in many chronic pain conditions. Relationship between chronic pain and sperm quality has not been investigated thoroughly and may provide an insight to better understanding, management and treatment of cases where chronic pain and male sub-fertility co-exist.Neat (fresh semen) and processed sperm from 15 males with orthopedic chronic pain (CP) were assessed and compared with 15 healthy age matched controls. Sperm analysis was performed using the SCA computer-aided sperm analyzer. There was no significant difference in any parameters of the neat semen between the pain and control group. However the percentage of non-progressive motile spermatozoa (type B) was significantly higher in the pain group (27.96) compared to the control group (15.96Straight line trajectories including linearity, straightness, wobble and beat cross frequency were also significantly higher in the processed sample of the CP group. This study demonstrated that chronic pain does not affect the sperm morphology, total concentration and motility based on conventional analysis but has significant influence at the level of sperm motion kinetics which could prove to be clinically valuable, prognostic indicators of successful fertilization. Maturation of sperm motility occurs during their transit through the epididymis and vas deferens regulated by androgens. As male gonadal hormones have an inhibitory, adaptive effect on the behavioral and neuronal responses to repeated nociceptive stimulation, it can be speculated that the observed difference in sperm kinematic parameters could be related to the alterations in serum sex hormone levels emanating from the chronic pain. Further studies are required to explain the possible mechanism of action of chronic pain on male fertility.

AB - Sex hormones play an important role in pain in many chronic pain conditions. Relationship between chronic pain and sperm quality has not been investigated thoroughly and may provide an insight to better understanding, management and treatment of cases where chronic pain and male sub-fertility co-exist.Neat (fresh semen) and processed sperm from 15 males with orthopedic chronic pain (CP) were assessed and compared with 15 healthy age matched controls. Sperm analysis was performed using the SCA computer-aided sperm analyzer. There was no significant difference in any parameters of the neat semen between the pain and control group. However the percentage of non-progressive motile spermatozoa (type B) was significantly higher in the pain group (27.96) compared to the control group (15.96Straight line trajectories including linearity, straightness, wobble and beat cross frequency were also significantly higher in the processed sample of the CP group. This study demonstrated that chronic pain does not affect the sperm morphology, total concentration and motility based on conventional analysis but has significant influence at the level of sperm motion kinetics which could prove to be clinically valuable, prognostic indicators of successful fertilization. Maturation of sperm motility occurs during their transit through the epididymis and vas deferens regulated by androgens. As male gonadal hormones have an inhibitory, adaptive effect on the behavioral and neuronal responses to repeated nociceptive stimulation, it can be speculated that the observed difference in sperm kinematic parameters could be related to the alterations in serum sex hormone levels emanating from the chronic pain. Further studies are required to explain the possible mechanism of action of chronic pain on male fertility.

M3 - Conference abstract in proceeding

BT - Official Program : SASP Annual Meeting 2015, Scandinavian Association for the Study of Pain, 13-14 April 2015, Stockholm, Sweden

PB - Scandinavian Association for the study of Pain

ER -

Dardmeh F, Alipour H, Nielsen HI, Rasmussen S, Yousefi JT, Ditlevsen N et al. Association between chronic pain and the sperm motion characteristics. In Official Program : SASP Annual Meeting 2015, Scandinavian Association for the Study of Pain, 13-14 April 2015, Stockholm, Sweden. Scandinavian Association for the study of Pain. 2015