Association Between Newly Diagnosed Atrial Fibrillation and Work Disability (from a Nationwide Danish Cohort Study)

Elin Danielsen Lunde*, Kirsten Fonager, Albert Marni Joensen, Søren Paaske Johnsen, Søren Lundbye-Christensen, Mogens Lytken Larsen, Sam Riahi

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review

2 Citations (Scopus)
29 Downloads (Pure)


It is previously shown that cardiovascular conditions have a negative effect on the ability to work. However, it is unknown if incident atrial fibrillation (AF) influences the ability to work. We examined the association between AF and the risk of work disability and the influence of socioeconomic factors. All Danish residents with a hospital diagnosis of AF and aged ≥30 and ≤63 years in the period January 1, 2000, to September 31, 2014, were included and matched 1:10 with an AF-free gender and age-matched random person from the general population. Permanent social security benefit was used as a marker of work disability. Risk difference (RD) and 95% confidence interval (95% CI) of work disability were calculated over 15 months. The analyses were furthermore stratified in low, medium, and high levels of socioeconomic factors. In total, 28,059 patients with AF and 312,667 matched reference persons were included. The risk of receiving permanent social security benefits within 15 months was 4.5% (4.3% to 4.8%) for the AF cohort and 1.3% (95% CI 1.3% to 1.4%) for the matched reference cohort. Adjusted RD (95% CI) was 2.3% (2.0% to 2.5%). Stratified on income, RDs were higher in low-income groups (adjusted RD 3.7% [95% CI 3.1% to 4.3%]) versus high-income groups (RD 1.3% [1.0% to 1.5%]). In conclusion, the risk of work disability within 15 months after incident AF was more than 3 times as high in patients with AF compared with the general population, especially when comparing individuals in lower socioeconomic strata.

Original languageEnglish
JournalThe American Journal of Cardiology
Pages (from-to)64-70
Number of pages7
Publication statusPublished - 15 Apr 2022

Bibliographical note

Copyright © 2021 The Author(s). Published by Elsevier Inc. All rights reserved.


  • Atrial Fibrillation/diagnosis
  • Cohort Studies
  • Denmark/epidemiology
  • Disabled Persons
  • Humans
  • Incidence
  • Risk Factors


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