Biolimus-eluting biodegradable polymer-coated stent versus durable polymer-coated sirolimus-eluting stent in unselected patients receiving percutaneous coronary intervention (SORT OUT V): a randomised non-inferiority trial

Evald Høj Christiansen; Lisette Okkels Jensen; Per Thayssen; Hans-Henrik Tilsted; Lars Romer Krusell; Knud Nørregaard Hansen; Anne Kjer Kaltoft; Michael Maeng; Steen Dalby Kristensen; Hans Erik Bøtker; Christian Juhl Terkelsen; Anton Boel Villadsen; Jan Ravkilde; Jens Aarøe; Morten Madsen; Leif Thuesen; Jens Flensted Lassen; Scandinavian Organization for Randomized Trials with Clinical Outcome (SORT OUT) V investigators

doi:10.1016/S0140-6736(12)61962-X

Biolimus-eluting biodegradable polymer-coated stent versus durable polymer-coated sirolimus-eluting stent in unselected patients receiving percutaneous coronary intervention (SORT OUT V): a randomised non-inferiority trial

Evald Høj Christiansen, Lisette Okkels Jensen, Per Thayssen, Hans-Henrik Tilsted, Lars Romer Krusell, Knud Nørregaard Hansen, Anne Kjer Kaltoft, Michael Maeng, Steen Dalby Kristensen, Hans Erik Bøtker, Christian Juhl Terkelsen, Anton Boel Villadsen, Jan Ravkilde, Jens Aarøe, Morten Madsen, Leif Thuesen, Jens Flensted Lassen, Scandinavian Organization for Randomized Trials with Clinical Outcome (SORT OUT) V investigators

Research output: Contribution to journal › Journal article › Research › peer-review

172 Citations (Scopus)

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Abstract

Third-generation biodegradable polymer drug-eluting stents might reduce the risk of stent thrombosis compared with first-generation permanent polymer drug-eluting stents. We aimed to further investigate the effects of a biodegradable polymer biolimus-eluting stent compared with a durable polymer-coated sirolimus-eluting stent in a population-based setting.

Original language	English
Journal	Lancet
Volume	381
Issue number	9867
Pages (from-to)	661-669
Number of pages	9
ISSN	0140-6736
DOIs	https://doi.org/10.1016/S0140-6736(12)61962-X
Publication status	Published - 23 Feb 2013

Keywords

Absorbable Implants
Acute Coronary Syndrome
Aged
Aspirin
Coated Materials, Biocompatible
Coronary Artery Disease
Coronary Thrombosis
Drug-Eluting Stents
Female
Humans
Male
Myocardial Infarction
Percutaneous Coronary Intervention
Platelet Aggregation Inhibitors
Polymers
Retreatment
Sirolimus

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10.1016/S0140-6736(12)61962-X

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Christiansen, E. H., Jensen, L. O., Thayssen, P., Tilsted, H-H., Krusell, L. R., Hansen, K. N., Kaltoft, A. K., Maeng, M., Kristensen, S. D., Bøtker, H. E., Terkelsen, C. J., Villadsen, A. B., Ravkilde, J., Aarøe, J., Madsen, M., Thuesen, L., Lassen, J. F., & Scandinavian Organization for Randomized Trials with Clinical Outcome (SORT OUT) V investigators (2013). Biolimus-eluting biodegradable polymer-coated stent versus durable polymer-coated sirolimus-eluting stent in unselected patients receiving percutaneous coronary intervention (SORT OUT V): a randomised non-inferiority trial. Lancet, 381(9867), 661-669. https://doi.org/10.1016/S0140-6736(12)61962-X

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title = "Biolimus-eluting biodegradable polymer-coated stent versus durable polymer-coated sirolimus-eluting stent in unselected patients receiving percutaneous coronary intervention (SORT OUT V): a randomised non-inferiority trial",

abstract = "Third-generation biodegradable polymer drug-eluting stents might reduce the risk of stent thrombosis compared with first-generation permanent polymer drug-eluting stents. We aimed to further investigate the effects of a biodegradable polymer biolimus-eluting stent compared with a durable polymer-coated sirolimus-eluting stent in a population-based setting.",

keywords = "Absorbable Implants, Acute Coronary Syndrome, Aged, Aspirin, Coated Materials, Biocompatible, Coronary Artery Disease, Coronary Thrombosis, Drug-Eluting Stents, Female, Humans, Male, Myocardial Infarction, Percutaneous Coronary Intervention, Platelet Aggregation Inhibitors, Polymers, Retreatment, Sirolimus",

author = "Christiansen, {Evald H{\o}j} and Jensen, {Lisette Okkels} and Per Thayssen and Hans-Henrik Tilsted and Krusell, {Lars Romer} and Hansen, {Knud N{\o}rregaard} and Kaltoft, {Anne Kjer} and Michael Maeng and Kristensen, {Steen Dalby} and B{\o}tker, {Hans Erik} and Terkelsen, {Christian Juhl} and Villadsen, {Anton Boel} and Jan Ravkilde and Jens Aar{\o}e and Morten Madsen and Leif Thuesen and Lassen, {Jens Flensted} and {Scandinavian Organization for Randomized Trials with Clinical Outcome (SORT OUT) V investigators}",

year = "2013",

month = feb,

day = "23",

doi = "10.1016/S0140-6736(12)61962-X",

language = "English",

volume = "381",

pages = "661--669",

journal = "Lancet",

issn = "0140-6736",

publisher = "TheLancet Publishing Group",

number = "9867",

}

Christiansen, EH, Jensen, LO, Thayssen, P, Tilsted, H-H, Krusell, LR, Hansen, KN, Kaltoft, AK, Maeng, M, Kristensen, SD, Bøtker, HE, Terkelsen, CJ, Villadsen, AB, Ravkilde, J, Aarøe, J, Madsen, M, Thuesen, L, Lassen, JF & Scandinavian Organization for Randomized Trials with Clinical Outcome (SORT OUT) V investigators 2013, 'Biolimus-eluting biodegradable polymer-coated stent versus durable polymer-coated sirolimus-eluting stent in unselected patients receiving percutaneous coronary intervention (SORT OUT V): a randomised non-inferiority trial', Lancet, vol. 381, no. 9867, pp. 661-669. https://doi.org/10.1016/S0140-6736(12)61962-X

Biolimus-eluting biodegradable polymer-coated stent versus durable polymer-coated sirolimus-eluting stent in unselected patients receiving percutaneous coronary intervention (SORT OUT V): a randomised non-inferiority trial. / Christiansen, Evald Høj; Jensen, Lisette Okkels; Thayssen, Per et al.
In: Lancet, Vol. 381, No. 9867, 23.02.2013, p. 661-669.

Research output: Contribution to journal › Journal article › Research › peer-review

TY - JOUR

T1 - Biolimus-eluting biodegradable polymer-coated stent versus durable polymer-coated sirolimus-eluting stent in unselected patients receiving percutaneous coronary intervention (SORT OUT V)

T2 - a randomised non-inferiority trial

AU - Christiansen, Evald Høj

AU - Jensen, Lisette Okkels

AU - Thayssen, Per

AU - Tilsted, Hans-Henrik

AU - Krusell, Lars Romer

AU - Hansen, Knud Nørregaard

AU - Kaltoft, Anne Kjer

AU - Maeng, Michael

AU - Kristensen, Steen Dalby

AU - Bøtker, Hans Erik

AU - Terkelsen, Christian Juhl

AU - Villadsen, Anton Boel

AU - Ravkilde, Jan

AU - Aarøe, Jens

AU - Madsen, Morten

AU - Thuesen, Leif

AU - Lassen, Jens Flensted

AU - Scandinavian Organization for Randomized Trials with Clinical Outcome (SORT OUT) V investigators

PY - 2013/2/23

Y1 - 2013/2/23

N2 - Third-generation biodegradable polymer drug-eluting stents might reduce the risk of stent thrombosis compared with first-generation permanent polymer drug-eluting stents. We aimed to further investigate the effects of a biodegradable polymer biolimus-eluting stent compared with a durable polymer-coated sirolimus-eluting stent in a population-based setting.

AB - Third-generation biodegradable polymer drug-eluting stents might reduce the risk of stent thrombosis compared with first-generation permanent polymer drug-eluting stents. We aimed to further investigate the effects of a biodegradable polymer biolimus-eluting stent compared with a durable polymer-coated sirolimus-eluting stent in a population-based setting.

KW - Absorbable Implants

KW - Acute Coronary Syndrome

KW - Aged

KW - Aspirin

KW - Coated Materials, Biocompatible

KW - Coronary Artery Disease

KW - Coronary Thrombosis

KW - Drug-Eluting Stents

KW - Female

KW - Humans

KW - Male

KW - Myocardial Infarction

KW - Percutaneous Coronary Intervention

KW - Platelet Aggregation Inhibitors

KW - Polymers

KW - Retreatment

KW - Sirolimus

U2 - 10.1016/S0140-6736(12)61962-X

DO - 10.1016/S0140-6736(12)61962-X

M3 - Journal article

C2 - 23374649

SN - 0140-6736

VL - 381

SP - 661

EP - 669

JO - Lancet

JF - Lancet

IS - 9867

ER -

Christiansen EH, Jensen LO, Thayssen P, Tilsted H-H, Krusell LR, Hansen KN et al. Biolimus-eluting biodegradable polymer-coated stent versus durable polymer-coated sirolimus-eluting stent in unselected patients receiving percutaneous coronary intervention (SORT OUT V): a randomised non-inferiority trial. Lancet. 2013 Feb 23;381(9867):661-669. doi: 10.1016/S0140-6736(12)61962-X