Blood Card and Vesicle-based Medical Tests

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Abstract

Venous blood is a convenient source of circulating extracellular vesicles (EVs). However, blood sampling requires authorized personnel and immediate purification of the vesicles. The present study demonstrate that intact EVs can in fact be obtained from dried blood card samples (or dried blood spots; DBS), which can be prepared by unauthorized personnel, or even at home by the user and shipped by regular mail. Intact EVs can be detected in extracts from dried blood spot samples even after prolonged storage.
Being able to isolate and characterize small EVs from DBS opens up a number of new opportunities such as monitoring of disease, e.g. progression of cancer and response to treatment, only with involvement of a lab technician and responsible clinician.
Original languageEnglish
Publication date2018
Publication statusPublished - 2018
EventDanish IP Fair 2018 - Industriens Hus, København, Denmark
Duration: 29 May 201829 May 2018
https://dipfair2018.b2match.io/

Conference

ConferenceDanish IP Fair 2018
LocationIndustriens Hus
Country/TerritoryDenmark
CityKøbenhavn
Period29/05/201829/05/2018
Internet address

Bibliographical note

Invention ID: MD04

Keywords

  • Extracellular vesicles
  • Blood sampling
  • Dried blood

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