Brain state-dependent peripheral nerve stimulation for plasticity induction in stroke patients

Andrew James Thomas Stevenson, Helle Rovsing Møller Jørgensen, Kåre Eg Severinsen, Susan Aliakbaryhosseinabadi, Ning Jiang, Dario Farina, Natalie Mrachacz-Kersting

Research output: Contribution to book/anthology/report/conference proceedingArticle in proceedingResearchpeer-review

Abstract

Artificial activation of peripheral afferent fibers, with the resulting sensory feedback timed to arrive at the peak negativity of the movement-related cortical potential, induces significant increases in the excitability of cortical projections to the target muscle in healthy individuals and chronic stroke patients. In the currently ongoing study, we applied this associative brain- computer interface paradigm to sub-acute stroke patients. Compared to a sham group, where the peripheral electrical stimulation intensity was below the acti- vation threshold of the sensory afferents, the associative intervention group displayed substantial increases in corticospinal excitability to the target muscle (tibialis anterior).
Original languageEnglish
Title of host publicationConverging Clinical and Engineering Research on Neurorehabilitation III : Proceedings of the 4th International Conference on NeuroRehabilitation (ICNR2018), October 16–20, 2018, Pisa, Italy
EditorsLorenzo Masia, Silvestro Micera, Metin Akay, José L. Pons
Number of pages5
PublisherSpringer
Publication date2019
Pages1066-1070
ISBN (Print)978-3-030-01844
ISBN (Electronic)978-3-030-01845-0
DOIs
Publication statusPublished - 2019
EventInternational Conference on Neurorehabilitation - Pisa, Italy
Duration: 16 Oct 201820 Oct 2018
http://www.icnr2018.org

Conference

ConferenceInternational Conference on Neurorehabilitation
CountryItaly
CityPisa
Period16/10/201820/10/2018
Internet address
SeriesBiosystems and Biorobotics
Number21
ISSN2195-3562

Fingerprint

Peripheral Nerves
Stroke
Sensory Thresholds
Brain-Computer Interfaces
Muscles
Sensory Feedback
Brain
Electric Stimulation
Cortical Excitability

Cite this

Stevenson, A. J. T., Jørgensen, H. R. M., Severinsen, K. E., Aliakbaryhosseinabadi, S., Jiang, N., Farina, D., & Mrachacz-Kersting, N. (2019). Brain state-dependent peripheral nerve stimulation for plasticity induction in stroke patients. In L. Masia, S. Micera, M. Akay, & J. L. Pons (Eds.), Converging Clinical and Engineering Research on Neurorehabilitation III: Proceedings of the 4th International Conference on NeuroRehabilitation (ICNR2018), October 16–20, 2018, Pisa, Italy (pp. 1066-1070). Springer. Biosystems and Biorobotics, No. 21 https://doi.org/10.1007/978-3-030-01845-0_213
Stevenson, Andrew James Thomas ; Jørgensen, Helle Rovsing Møller ; Severinsen, Kåre Eg ; Aliakbaryhosseinabadi, Susan ; Jiang, Ning ; Farina, Dario ; Mrachacz-Kersting, Natalie. / Brain state-dependent peripheral nerve stimulation for plasticity induction in stroke patients. Converging Clinical and Engineering Research on Neurorehabilitation III: Proceedings of the 4th International Conference on NeuroRehabilitation (ICNR2018), October 16–20, 2018, Pisa, Italy. editor / Lorenzo Masia ; Silvestro Micera ; Metin Akay ; José L. Pons. Springer, 2019. pp. 1066-1070 (Biosystems and Biorobotics; No. 21).
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abstract = "Artificial activation of peripheral afferent fibers, with the resulting sensory feedback timed to arrive at the peak negativity of the movement-related cortical potential, induces significant increases in the excitability of cortical projections to the target muscle in healthy individuals and chronic stroke patients. In the currently ongoing study, we applied this associative brain- computer interface paradigm to sub-acute stroke patients. Compared to a sham group, where the peripheral electrical stimulation intensity was below the acti- vation threshold of the sensory afferents, the associative intervention group displayed substantial increases in corticospinal excitability to the target muscle (tibialis anterior).",
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Stevenson, AJT, Jørgensen, HRM, Severinsen, KE, Aliakbaryhosseinabadi, S, Jiang, N, Farina, D & Mrachacz-Kersting, N 2019, Brain state-dependent peripheral nerve stimulation for plasticity induction in stroke patients. in L Masia, S Micera, M Akay & JL Pons (eds), Converging Clinical and Engineering Research on Neurorehabilitation III: Proceedings of the 4th International Conference on NeuroRehabilitation (ICNR2018), October 16–20, 2018, Pisa, Italy. Springer, Biosystems and Biorobotics, no. 21, pp. 1066-1070, International Conference on Neurorehabilitation, Pisa, Italy, 16/10/2018. https://doi.org/10.1007/978-3-030-01845-0_213

Brain state-dependent peripheral nerve stimulation for plasticity induction in stroke patients. / Stevenson, Andrew James Thomas; Jørgensen, Helle Rovsing Møller; Severinsen, Kåre Eg; Aliakbaryhosseinabadi, Susan; Jiang, Ning; Farina, Dario; Mrachacz-Kersting, Natalie.

Converging Clinical and Engineering Research on Neurorehabilitation III: Proceedings of the 4th International Conference on NeuroRehabilitation (ICNR2018), October 16–20, 2018, Pisa, Italy. ed. / Lorenzo Masia; Silvestro Micera; Metin Akay; José L. Pons. Springer, 2019. p. 1066-1070.

Research output: Contribution to book/anthology/report/conference proceedingArticle in proceedingResearchpeer-review

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Stevenson AJT, Jørgensen HRM, Severinsen KE, Aliakbaryhosseinabadi S, Jiang N, Farina D et al. Brain state-dependent peripheral nerve stimulation for plasticity induction in stroke patients. In Masia L, Micera S, Akay M, Pons JL, editors, Converging Clinical and Engineering Research on Neurorehabilitation III: Proceedings of the 4th International Conference on NeuroRehabilitation (ICNR2018), October 16–20, 2018, Pisa, Italy. Springer. 2019. p. 1066-1070. (Biosystems and Biorobotics; No. 21). https://doi.org/10.1007/978-3-030-01845-0_213