Computational and cellular studies reveal structural destabilization and degradation of MLH1 variants in Lynch syndrome

Amanda B Abildgaard, Amelie Stein, Sofie V Nielsen, Katrine Schultz-Knudsen, Elena Papaleo, Amruta Shrikhande, Eva R Hoffmann, Inge Bernstein, Anne-Marie Gerdes, Masanobu Takahashi, Chikashi Ishioka, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen

Research output: Contribution to journalJournal articleResearchpeer-review

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Original languageEnglish
Article numbere49138
JournaleLife
Volume8
Number of pages28
ISSN2050-084X
DOIs
Publication statusPublished - Nov 2019

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Abildgaard, A. B., Stein, A., Nielsen, S. V., Schultz-Knudsen, K., Papaleo, E., Shrikhande, A., ... Hartmann-Petersen, R. (2019). Computational and cellular studies reveal structural destabilization and degradation of MLH1 variants in Lynch syndrome. eLife, 8, [e49138]. https://doi.org/10.7554/eLife.49138
Abildgaard, Amanda B ; Stein, Amelie ; Nielsen, Sofie V ; Schultz-Knudsen, Katrine ; Papaleo, Elena ; Shrikhande, Amruta ; Hoffmann, Eva R ; Bernstein, Inge ; Gerdes, Anne-Marie ; Takahashi, Masanobu ; Ishioka, Chikashi ; Lindorff-Larsen, Kresten ; Hartmann-Petersen, Rasmus. / Computational and cellular studies reveal structural destabilization and degradation of MLH1 variants in Lynch syndrome. In: eLife. 2019 ; Vol. 8.
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author = "Abildgaard, {Amanda B} and Amelie Stein and Nielsen, {Sofie V} and Katrine Schultz-Knudsen and Elena Papaleo and Amruta Shrikhande and Hoffmann, {Eva R} and Inge Bernstein and Anne-Marie Gerdes and Masanobu Takahashi and Chikashi Ishioka and Kresten Lindorff-Larsen and Rasmus Hartmann-Petersen",
year = "2019",
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Abildgaard, AB, Stein, A, Nielsen, SV, Schultz-Knudsen, K, Papaleo, E, Shrikhande, A, Hoffmann, ER, Bernstein, I, Gerdes, A-M, Takahashi, M, Ishioka, C, Lindorff-Larsen, K & Hartmann-Petersen, R 2019, 'Computational and cellular studies reveal structural destabilization and degradation of MLH1 variants in Lynch syndrome', eLife, vol. 8, e49138. https://doi.org/10.7554/eLife.49138

Computational and cellular studies reveal structural destabilization and degradation of MLH1 variants in Lynch syndrome. / Abildgaard, Amanda B; Stein, Amelie; Nielsen, Sofie V; Schultz-Knudsen, Katrine; Papaleo, Elena; Shrikhande, Amruta; Hoffmann, Eva R; Bernstein, Inge; Gerdes, Anne-Marie; Takahashi, Masanobu; Ishioka, Chikashi; Lindorff-Larsen, Kresten; Hartmann-Petersen, Rasmus.

In: eLife, Vol. 8, e49138, 11.2019.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - Computational and cellular studies reveal structural destabilization and degradation of MLH1 variants in Lynch syndrome

AU - Abildgaard, Amanda B

AU - Stein, Amelie

AU - Nielsen, Sofie V

AU - Schultz-Knudsen, Katrine

AU - Papaleo, Elena

AU - Shrikhande, Amruta

AU - Hoffmann, Eva R

AU - Bernstein, Inge

AU - Gerdes, Anne-Marie

AU - Takahashi, Masanobu

AU - Ishioka, Chikashi

AU - Lindorff-Larsen, Kresten

AU - Hartmann-Petersen, Rasmus

PY - 2019/11

Y1 - 2019/11

U2 - 10.7554/eLife.49138

DO - 10.7554/eLife.49138

M3 - Journal article

C2 - 31697235

VL - 8

JO - eLife

JF - eLife

SN - 2050-084X

M1 - e49138

ER -

Abildgaard AB, Stein A, Nielsen SV, Schultz-Knudsen K, Papaleo E, Shrikhande A et al. Computational and cellular studies reveal structural destabilization and degradation of MLH1 variants in Lynch syndrome. eLife. 2019 Nov;8. e49138. https://doi.org/10.7554/eLife.49138