Detecting reduced renal function in children: Comparison of GFR-models and serum markers

Trine Borup Andersen; Lars Jødal; Erland J Erlandsen; Anni Morsing; Jørgen Frøkiær; Jens Brøchner-Mortensen

doi:10.1007/s00467-012-2268-8

Detecting reduced renal function in children: Comparison of GFR-models and serum markers

Trine Borup Andersen, Lars Jødal, Erland J Erlandsen, Anni Morsing, Jørgen Frøkiær, Jens Brøchner-Mortensen

Research output: Contribution to journal › Journal article › Research › peer-review

13 Citations (Scopus)

Abstract

The aim of this study was to compare the ability of renal indicators [serum creatinine (SCr), cystatin C (SCysC)] and glomerular filtration rate (GFR)-models to discriminate normal and reduced renal function. As a single cut-off level will always lead to false classifications, we propose using two cut-off levels, dividing renal function into normal or reduced, with an intermediate "gray zone" of indeterminable results.

Original language	English
Journal	Pediatric Nephrology
Volume	28
Issue number	1
Pages (from-to)	83-92
Number of pages	10
ISSN	0931-041X
DOIs	https://doi.org/10.1007/s00467-012-2268-8
Publication status	Published - Jan 2013

Keywords

Adolescent
Child
Child, Preschool
Creatinine
Cystatin C
Female
Glomerular Filtration Rate
Humans
Kidney Diseases
Kidney Function Tests
Male

Access to Document

10.1007/s00467-012-2268-8

AUB Link

Search for the material in Aalborg University Library's search engine

Cite this

@article{521f103cf11b46f6ac611f581bedb98d,

title = "Detecting reduced renal function in children: Comparison of GFR-models and serum markers",

abstract = "The aim of this study was to compare the ability of renal indicators [serum creatinine (SCr), cystatin C (SCysC)] and glomerular filtration rate (GFR)-models to discriminate normal and reduced renal function. As a single cut-off level will always lead to false classifications, we propose using two cut-off levels, dividing renal function into normal or reduced, with an intermediate {"}gray zone{"} of indeterminable results.",

keywords = "Adolescent, Child, Child, Preschool, Creatinine, Cystatin C, Female, Glomerular Filtration Rate, Humans, Kidney Diseases, Kidney Function Tests, Male",

author = "Andersen, {Trine Borup} and Lars J{\o}dal and Erlandsen, {Erland J} and Anni Morsing and J{\o}rgen Fr{\o}ki{\ae}r and Jens Br{\o}chner-Mortensen",

year = "2013",

month = jan,

doi = "10.1007/s00467-012-2268-8",

language = "English",

volume = "28",

pages = "83--92",

journal = "Pediatric Nephrology",

issn = "0931-041X",

publisher = "Springer",

number = "1",

}

TY - JOUR

T1 - Detecting reduced renal function in children

T2 - Comparison of GFR-models and serum markers

AU - Andersen, Trine Borup

AU - Jødal, Lars

AU - Erlandsen, Erland J

AU - Morsing, Anni

AU - Frøkiær, Jørgen

AU - Brøchner-Mortensen, Jens

PY - 2013/1

Y1 - 2013/1

N2 - The aim of this study was to compare the ability of renal indicators [serum creatinine (SCr), cystatin C (SCysC)] and glomerular filtration rate (GFR)-models to discriminate normal and reduced renal function. As a single cut-off level will always lead to false classifications, we propose using two cut-off levels, dividing renal function into normal or reduced, with an intermediate "gray zone" of indeterminable results.

AB - The aim of this study was to compare the ability of renal indicators [serum creatinine (SCr), cystatin C (SCysC)] and glomerular filtration rate (GFR)-models to discriminate normal and reduced renal function. As a single cut-off level will always lead to false classifications, we propose using two cut-off levels, dividing renal function into normal or reduced, with an intermediate "gray zone" of indeterminable results.

KW - Adolescent

KW - Child

KW - Child, Preschool

KW - Creatinine

KW - Cystatin C

KW - Female

KW - Glomerular Filtration Rate

KW - Humans

KW - Kidney Diseases

KW - Kidney Function Tests

KW - Male

U2 - 10.1007/s00467-012-2268-8

DO - 10.1007/s00467-012-2268-8

M3 - Journal article

C2 - 22945867

SN - 0931-041X

VL - 28

SP - 83

EP - 92

JO - Pediatric Nephrology

JF - Pediatric Nephrology

IS - 1

ER -

Detecting reduced renal function in children: Comparison of GFR-models and serum markers

Abstract

Keywords

Access to Document

AUB Link

Fingerprint

Cite this