Determinants of plasma PTH and their implication for defining a reference interval

Lars Rejnmark; Peter Vestergaard; Lene Heickendorff; Leif Mosekilde

doi:10.1111/j.1365-2265.2010.03894.x

Determinants of plasma PTH and their implication for defining a reference interval

Lars Rejnmark, Peter Vestergaard, Lene Heickendorff, Leif Mosekilde

Research output: Contribution to journal › Journal article › Research › peer-review

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Abstract

To improve the diagnostic sensitivity of PTH measurements, more data on the upper limit of the reference interval for PTH levels were requested at a recent international consensus conference. As PTH levels vary inversely with plasma 25-hydroxyvitamin D (25OHD) levels and as vitamin D insufficiency is widespread, particular attention should be given to the influence of low vitamin D levels on the PTH reference interval. AIM, DESIGN AND METHODS: In a cross-sectional design, including 2316 women aged 17-84, we determined 95% reference interval using a nonparametric approach and studied the effects of potential predictors on plasma PTH levels.

Original language	English
Journal	Clinical Endocrinology
Volume	74
Pages (from-to)	37-43
Number of pages	7
ISSN	0300-0664
DOIs	https://doi.org/10.1111/j.1365-2265.2010.03894.x
Publication status	Published - 1 Jan 2011
Externally published	Yes

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title = "Determinants of plasma PTH and their implication for defining a reference interval",

abstract = "To improve the diagnostic sensitivity of PTH measurements, more data on the upper limit of the reference interval for PTH levels were requested at a recent international consensus conference. As PTH levels vary inversely with plasma 25-hydroxyvitamin D (25OHD) levels and as vitamin D insufficiency is widespread, particular attention should be given to the influence of low vitamin D levels on the PTH reference interval. AIM, DESIGN AND METHODS: In a cross-sectional design, including 2316 women aged 17-84, we determined 95% reference interval using a nonparametric approach and studied the effects of potential predictors on plasma PTH levels.",

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AU - Rejnmark, Lars

AU - Vestergaard, Peter

AU - Heickendorff, Lene

AU - Mosekilde, Leif

PY - 2011/1/1

Y1 - 2011/1/1

N2 - To improve the diagnostic sensitivity of PTH measurements, more data on the upper limit of the reference interval for PTH levels were requested at a recent international consensus conference. As PTH levels vary inversely with plasma 25-hydroxyvitamin D (25OHD) levels and as vitamin D insufficiency is widespread, particular attention should be given to the influence of low vitamin D levels on the PTH reference interval. AIM, DESIGN AND METHODS: In a cross-sectional design, including 2316 women aged 17-84, we determined 95% reference interval using a nonparametric approach and studied the effects of potential predictors on plasma PTH levels.

AB - To improve the diagnostic sensitivity of PTH measurements, more data on the upper limit of the reference interval for PTH levels were requested at a recent international consensus conference. As PTH levels vary inversely with plasma 25-hydroxyvitamin D (25OHD) levels and as vitamin D insufficiency is widespread, particular attention should be given to the influence of low vitamin D levels on the PTH reference interval. AIM, DESIGN AND METHODS: In a cross-sectional design, including 2316 women aged 17-84, we determined 95% reference interval using a nonparametric approach and studied the effects of potential predictors on plasma PTH levels.

U2 - 10.1111/j.1365-2265.2010.03894.x

DO - 10.1111/j.1365-2265.2010.03894.x

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SP - 37

EP - 43

JO - Clinical Endocrinology

JF - Clinical Endocrinology

ER -

Determinants of plasma PTH and their implication for defining a reference interval

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