Research output per year
Research output per year
Gustav Valentin Gade*, Martin G Jørgensen, Jesper Ryg, Tahir Masud, Lasse Hjort Jakobsen, Stig Andersen
Research output: Contribution to journal › Journal article › Research › peer-review
BACKGROUND: Falls are the leading cause of fatal and non-fatal injuries in older adults, and attention to falls prevention is imperative. Prognostic models identifying high-risk individuals could guide fall-preventive interventions in the rapidly growing older population. We aimed to develop a prognostic prediction model on falls rate in community-dwelling older adults.
METHODS: Design: prospective cohort study with 12 months follow-up and participants recruited from June 14, 2018, to July 18, 2019.
SETTING: general population.
SUBJECTS: community-dwelling older adults aged 75+ years, without dementia or acute illness, and able to stand unsupported for one minute.
OUTCOME: fall rate for 12 months.
STATISTICAL METHODS: candidate predictors were physical and cognitive tests along with self-report questionnaires. We developed a Poisson model using least absolute shrinkage and selection operator penalization, leave-one-out cross-validation, and bootstrap resampling with 1000 iterations.
RESULTS: Sample size at study start and end was 241 and 198 (82%), respectively. The number of fallers was 87 (36%), and the fall rate was 0.94 falls per person-year. Predictors included in the final model were educational level, dizziness, alcohol consumption, prior falls, self-perceived falls risk, disability, and depressive symptoms. Mean absolute error (95% CI) was 0.88 falls (0.71-1.16).
CONCLUSION: We developed a falls prediction model for community-dwelling older adults in a general population setting. The model was developed by selecting predictors from among physical and cognitive tests along with self-report questionnaires. The final model included only the questionnaire-based predictors, and its predictions had an average imprecision of less than one fall, thereby making it appropriate for clinical practice. Future external validation is needed.
TRIAL REGISTRATION: Clinicaltrials.gov ( NCT03608709 ).
Original language | English |
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Article number | 402 |
Journal | BMC Geriatrics |
Volume | 21 |
Issue number | 1 |
Number of pages | 12 |
ISSN | 1471-2318 |
DOIs | |
Publication status | Published - 30 Jun 2021 |
Jørgensen, M. G. (Creator), Ryg, J. (Creator), Gade, G. V. (Creator), Masud, T. (Creator), Andersen, L. S. (Creator) & Jakobsen, L. H. K. (Creator), Figshare, 2021
DOI: 10.6084/m9.figshare.14889895.v1, https://doi.org/10.6084%2Fm9.figshare.14889895.v1
Dataset
Gade, G. V. (Creator), Jørgensen, M. G. (Creator), Ryg, J. (Creator), Masud, T. (Creator), Jakobsen, L. H. K. (Creator) & Andersen, L. S. (Creator), Figshare, 2021
DOI: 10.6084/m9.figshare.c.5492320.v1, https://springernature.figshare.com/collections/Development_of_a_multivariable_prognostic_PREdiction_model_for_1-year_risk_of_FALLing_in_a_cohort_of_community-dwelling_older_adults_aged_75_years_and_above_PREFALL_/5492320/1
Dataset
Gade, G. V. (Creator), Jørgensen, M. G. (Creator), Ryg, J. (Creator), Masud, T. (Creator), Jakobsen, L. H. K. (Creator) & Andersen, L. S. (Creator), Figshare, 2021
DOI: 10.6084/m9.figshare.c.5492320, https://springernature.figshare.com/collections/Development_of_a_multivariable_prognostic_PREdiction_model_for_1-year_risk_of_FALLing_in_a_cohort_of_community-dwelling_older_adults_aged_75_years_and_above_PREFALL_/5492320
Dataset