TY - JOUR
T1 - Dietary patterns generated by the Treelet Transform and risk of stroke
T2 - a Danish cohort study
AU - Frederiksen, Signe B
AU - Themsen, Heidi H
AU - Overvad, Kim
AU - Dahm, Christina C
PY - 2021/1
Y1 - 2021/1
N2 - OBJECTIVE: To relate empirically derived dietary patterns identified using the Treelet Transform (TT) to risk of stroke.DESIGN: A prospective cohort study using the Danish Diet, Cancer and Health cohort. Dietary information was obtained in 1993-1997 using a validated semi-quantitative FFQ. Incident stroke diagnoses, obtained from the Danish National Patient Register, were verified by record review. Dietary patterns were generated using TT, and participants were categorised into quintiles based on their adherence to each pattern. Sex-specific Cox proportional hazard models estimated associations between dietary patterns and stroke.SETTING: Denmark.PARTICIPANTS: 55 061 men and women aged 50-64 years at the time of enrolment.RESULTS: Three dietary patterns explaining 15·4 % of the total variance were identified: a Prudent pattern, a Western pattern and a Wine & Snacks pattern. During a follow-up time of 10 years, 1513 cases occurred. Comparing the highest to lowest quintiles of intake, adherence to a Prudent pattern was inversely associated with stroke (HRmen 0·74, 95 % CI 0·60, 0·91; HRwomen 0·82, 95 % CI 0·62, 1·08), while adherence to a Western pattern was associated with greater risk (HRmen 1·61, 95 % CI 1·23, 2·10; HRwomen 2·01, 95 % CI 1·48, 2·72). No association was found for a Wine & Snacks pattern for women, but a weak inverse association was found for men (HR 0·81, 95 % CI 0·67, 0·99).CONCLUSIONS: The results of this study are broadly in line with current recommendations for a healthy diet to prevent stroke.
AB - OBJECTIVE: To relate empirically derived dietary patterns identified using the Treelet Transform (TT) to risk of stroke.DESIGN: A prospective cohort study using the Danish Diet, Cancer and Health cohort. Dietary information was obtained in 1993-1997 using a validated semi-quantitative FFQ. Incident stroke diagnoses, obtained from the Danish National Patient Register, were verified by record review. Dietary patterns were generated using TT, and participants were categorised into quintiles based on their adherence to each pattern. Sex-specific Cox proportional hazard models estimated associations between dietary patterns and stroke.SETTING: Denmark.PARTICIPANTS: 55 061 men and women aged 50-64 years at the time of enrolment.RESULTS: Three dietary patterns explaining 15·4 % of the total variance were identified: a Prudent pattern, a Western pattern and a Wine & Snacks pattern. During a follow-up time of 10 years, 1513 cases occurred. Comparing the highest to lowest quintiles of intake, adherence to a Prudent pattern was inversely associated with stroke (HRmen 0·74, 95 % CI 0·60, 0·91; HRwomen 0·82, 95 % CI 0·62, 1·08), while adherence to a Western pattern was associated with greater risk (HRmen 1·61, 95 % CI 1·23, 2·10; HRwomen 2·01, 95 % CI 1·48, 2·72). No association was found for a Wine & Snacks pattern for women, but a weak inverse association was found for men (HR 0·81, 95 % CI 0·67, 0·99).CONCLUSIONS: The results of this study are broadly in line with current recommendations for a healthy diet to prevent stroke.
KW - Dietary patterns
KW - Exploratory analysis
KW - Stroke
KW - Treelet Transform
UR - http://www.scopus.com/inward/record.url?scp=85082335936&partnerID=8YFLogxK
U2 - 10.1017/S1368980019004324
DO - 10.1017/S1368980019004324
M3 - Journal article
C2 - 32204745
SN - 1368-9800
VL - 24
SP - 84
EP - 94
JO - Public Health Nutrition
JF - Public Health Nutrition
IS - 1
ER -