Does Retrograde Femoral Nailing through a Normal Physis Impair Growth? An Experimental Porcine Model

Ahmed A Abood, Ole Rahbek, Morten L Olesen, Bjørn B Christensen, Bjarne Møller-Madsen, Søren Kold

Research output: Contribution to journalJournal articleResearchpeer-review

1 Citation (Scopus)
34 Downloads (Pure)

Abstract

Materials and methods: The study was carried out using an experimental porcine model. Eleven juvenile female porcines were randomized for insertion of a retrograde femoral nail in one limb. The other limb acted as a control. The animals were housed for 8 weeks before the nail was removed and housed for 8 additional weeks, that is, 16 weeks in total. Growth was assessed by interphyseal distance on 3D magnetic resonance imaging (MRI) after 16 weeks and the operated limb was compared to the non-operated limb. Histomorphometric analysis of the physeal canal was performed.

Results: No difference in longitudinal growth was observed when comparing the operated femur to the non-operated femur using MRI after 16 weeks. No osseous tissue crossing the physis was observed on MRI or histology. The empty canal in the physis after nail removal was filled with fibrous tissue 16 weeks after primary surgery.

Conclusion: Growth was not impaired and no bone bridges were seen on MRI or histology 16 weeks after insertion and later removal of the retrograde femoral nail.

Clinical significance: The insertion of a retrograde intramedullary femoral nail centrally through the physis and later removal might be safe, however, long-term follow-up is needed.

Aim and objective: The insertion of an intramedullary nail may be beneficial in certain cases of leg length discrepancy (LLD) in children. However, it is unknown if the physeal injury due to the surgery may cause bone bridge formation and thereby growth arrest after removal. This study aimed to assess longitudinal interphyseal growth 16 weeks after insertion and later removal of a retrograde femoral nail passing through the physis. Moreover, to analyse the tissue forming in the empty physeal canal after removal of the nail.

How to cite this article: Abood AA, Rahbek O, Olesen ML, et al. Does Retrograde Femoral Nailing through a Normal Physis Impair Growth? An Experimental Porcine Model. Strategies Trauma Limb Reconstr 2021;16(1):8-13.

Original languageEnglish
JournalStrategies in Trauma and Limb Reconstruction
Volume16
Issue number1
Pages (from-to)8-13
Number of pages6
ISSN1828-8936
DOIs
Publication statusPublished - 31 Jul 2021

Bibliographical note

Copyright © 2021; Jaypee Brothers Medical Publishers (P) Ltd.

Keywords

  • Children
  • Intramedullary nail
  • Leg length discrepancy

Fingerprint

Dive into the research topics of 'Does Retrograde Femoral Nailing through a Normal Physis Impair Growth? An Experimental Porcine Model'. Together they form a unique fingerprint.

Cite this