TY - JOUR
T1 - EHRA expert consensus document on the management of arrhythmias in frailty syndrome, endorsed by the Heart Rhythm Society (HRS), Asia Pacific Heart Rhythm Society (APHRS), Latin America Heart Rhythm Society (LAHRS), and Cardiac Arrhythmia Society of Southern Africa (CASSA)
AU - Savelieva, Irina
AU - Fumagalli, Stefano
AU - Kenny, Rose Anne
AU - Anker, Stefan
AU - Benetos, Athanase
AU - Boriani, Giuseppe
AU - Bunch, Jared
AU - Dagres, Nikolaos
AU - Dubner, Sergio
AU - Fauchier, Laurent
AU - Ferrucci, Luigi
AU - Israel, Carsten
AU - Kamel, Hooman
AU - Lane, Deirdre A.
AU - Lip, Gregory Y. H.
AU - Marchionni, Niccolò
AU - Obel, Israel
AU - Okumura, Ken
AU - Olshansky, Brian
AU - Potpara, Tatjana
AU - Stiles, Martin K.
AU - Tamargo, Juan
AU - Ungar, Andrea
AU - Document Reviewers:
A2 - Kosiuk, Jedrzej
A2 - Larsen, Torben Bjerregaard
A2 - Dinov, Borislav
A2 - Estner, Heidi
A2 - Garcia, Rodrigue
A2 - Moscoso Costa, Francisco Manuel
A2 - Lampert, Rachel
A2 - Lin, Yenn-Jiang
A2 - Chin, Ashley
A2 - Rodriguez, Heliodoro Antonio
A2 - Strandberg, Timo
A2 - Grodzicki, Tomasz
N1 - © The Author(s) 2023. Published by Oxford University Press on behalf of the European Society of Cardiology.
PY - 2023/4/15
Y1 - 2023/4/15
N2 - There is an increasing proportion of the general population surviving to old age with significant chronic disease, multi-morbidity, and disability. The prevalence of pre-frail state and frailty syndrome increases exponentially with advancing age and is associated with greater morbidity, disability, hospitalization, institutionalization, mortality, and health care resource use. Frailty represents a global problem, making early identification, evaluation, and treatment to prevent the cascade of events leading from functional decline to disability and death, one of the challenges of geriatric and general medicine. Cardiac arrhythmias are common in advancing age, chronic illness, and frailty and include a broad spectrum of rhythm and conduction abnormalities. However, no systematic studies or recommendations on the management of arrhythmias are available specifically for the elderly and frail population, and the uptake of many effective antiarrhythmic therapies in these patients remains the slowest. This European Heart Rhythm Association (EHRA) consensus document focuses on the biology of frailty, common comorbidities, and methods of assessing frailty, in respect to a specific issue of arrhythmias and conduction disease, provide evidence base advice on the management of arrhythmias in patients with frailty syndrome, and identifies knowledge gaps and directions for future research.
AB - There is an increasing proportion of the general population surviving to old age with significant chronic disease, multi-morbidity, and disability. The prevalence of pre-frail state and frailty syndrome increases exponentially with advancing age and is associated with greater morbidity, disability, hospitalization, institutionalization, mortality, and health care resource use. Frailty represents a global problem, making early identification, evaluation, and treatment to prevent the cascade of events leading from functional decline to disability and death, one of the challenges of geriatric and general medicine. Cardiac arrhythmias are common in advancing age, chronic illness, and frailty and include a broad spectrum of rhythm and conduction abnormalities. However, no systematic studies or recommendations on the management of arrhythmias are available specifically for the elderly and frail population, and the uptake of many effective antiarrhythmic therapies in these patients remains the slowest. This European Heart Rhythm Association (EHRA) consensus document focuses on the biology of frailty, common comorbidities, and methods of assessing frailty, in respect to a specific issue of arrhythmias and conduction disease, provide evidence base advice on the management of arrhythmias in patients with frailty syndrome, and identifies knowledge gaps and directions for future research.
KW - Aged
KW - Arrhythmias, Cardiac/diagnosis
KW - Cardiac Conduction System Disease
KW - Consensus
KW - Frail Elderly
KW - Frailty/diagnosis
KW - Humans
KW - Latin America
KW - Antiarrhythmic drugs
KW - Cardiac resynchronization therapy
KW - Implantable cardioverter-defibrillator
KW - Frailty syndrome
KW - Consensus document
KW - European Heart Rhythm Association
KW - Frailty
KW - Cognitive impairment
KW - Frailty domains
KW - Heart failure
KW - Position paper
KW - Anticoagulants
KW - Stroke
KW - Atrial fibrillation
KW - Pre-frailty state
KW - Ventricular tachycardia
KW - Cachexia
KW - Ablation
KW - Pacemaker
KW - Frailty assessment
KW - Cardiac resynchronization therapy-defibrillator
KW - Elderly
KW - Arrhythmias
UR - http://www.scopus.com/inward/record.url?scp=85159547318&partnerID=8YFLogxK
U2 - 10.1093/europace/euac123
DO - 10.1093/europace/euac123
M3 - Journal article
C2 - 37061780
SN - 1099-5129
VL - 25
SP - 1249
EP - 1276
JO - Europace
JF - Europace
IS - 4
ER -