Estimating the probability of allelic drop-out of STR alleles in forensic genetics

Torben Tvedebrink, Poul Svante Eriksen, Helle Smidt Mogensen, Niels Morling

Research output: Contribution to journalJournal articleResearchpeer-review

80 Citations (Scopus)

Abstract

In crime cases with available DNA evidence, the amount of DNA is often sparse due to the setting of the crime. In such cases, allelic drop-oue or more true alleles in STR typing is possible. We present a statistical model for estimating the per locus and overall probability of allelic drop-out using the results of all STR loci in the case sample as reference. The methodology of logistic regression is appropriate for this analysis, and we demonstrate how to incorporate this in a forensic genetic framework.t of on
Original languageEnglish
JournalForensic Science International: Genetics
Volume3
Issue number4
Pages (from-to)222-226
ISSN1872-4973
DOIs
Publication statusPublished - 2009

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Forensic Genetics
Crime
Alleles
DNA
Statistical Models
Logistic Models

Cite this

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Estimating the probability of allelic drop-out of STR alleles in forensic genetics. / Tvedebrink, Torben; Eriksen, Poul Svante; Mogensen, Helle Smidt; Morling, Niels.

In: Forensic Science International: Genetics, Vol. 3, No. 4, 2009, p. 222-226.

Research output: Contribution to journalJournal articleResearchpeer-review

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AU - Tvedebrink, Torben

AU - Eriksen, Poul Svante

AU - Mogensen, Helle Smidt

AU - Morling, Niels

PY - 2009

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JF - Forensic Science International: Genetics

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