Exercise and Cardiac Function by Tissue Doppler Imaging. The Copenhagen City Heart Study

Gowsini Joseph, Peter Sogaard, Gitte Nielsen, Tor Biering-Sørensen, Peter Schnohr, Jan Skov Jensen, Rasmus Møgelvang

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

45 Downloads (Pure)

Abstract

Introduction: TDI (Tissue Doppler Imaging) is a sensitive marker of myocardial dysfunction and mortality in heart disease and in the general population. Regular physical activity is associated with risk reduction in coronary heart disease and mortality. There is a need for studies to clarify whether exercise has beneficial effects on cardiac function.Hypothesis: Regular physical exercise is associated with better cardiac function measured by TDI in the general populationMethods: 2,162 persons from the general population were examined by echocardiography and TDI. Peak systolic (s'), early diastolic (e') and late diastolic (a') velocities were measured by color TDI. Longitudinal displacement (LD) was calculated from the velocity curve during ejection. Statistical tests were performed by linear univariate and multivariable regression analyses, in relation to age groups (lt;50years, 50-65 years, gt;65 years) and physical activity level: I (inactivity), II (light activity), III (moderate activity) and IV (high-level activity). These levels were graded from the physical activity questionnaire, which contained information about activity level at work and in leisure time.Results: Participants agedlt;50 years had a significantly higher level of e' and LD in the most active group: e'=11.0 (textpm standard deviation, SD=2.0), plt;0.001; LD=12.8 (SD=2.1), plt;0.003. This pattern remained significant after adjusting for sex, hypertension, diabetes, and ischaemic heart disease and after Bonferroni correction. For e', there was significant interaction between age and activity level (plt;0.001), which supports the findings of better cardiac function with increasing activity among the young age group.Conclusion: In the general population, the association between increasing level of exercise and better cardiac function was found only in the youngest age group ( lt;50 years old). Among the elder age groups higher level of activity was not correlated to better cardiac function.Author Disclosures: G. Joseph: None. P. Sogaard: Other Research Support; Modest; GE Healthcare. G. Nielsen: None. T. Biering-Sorensen: None. P. Schnohr: None. J. Skov Jensen: None. R. Mogelvang: Other Research Support; Modest; GE Healthcare.
Original languageEnglish
Publication date2016
Publication statusPublished - 2016
Event AHA Scientific Sessions 2016 - New Orleans, United States
Duration: 12 Nov 201616 Nov 2016

Conference

Conference AHA Scientific Sessions 2016
CountryUnited States
CityNew Orleans
Period12/11/201616/11/2016

Cite this

Joseph, G., Sogaard, P., Nielsen, G., Biering-Sørensen, T., Schnohr, P., Skov Jensen, J., & Møgelvang, R. (2016). Exercise and Cardiac Function by Tissue Doppler Imaging. The Copenhagen City Heart Study. Poster presented at AHA Scientific Sessions 2016, New Orleans, United States.
Joseph, Gowsini ; Sogaard, Peter ; Nielsen, Gitte ; Biering-Sørensen, Tor ; Schnohr, Peter ; Skov Jensen, Jan ; Møgelvang, Rasmus. / Exercise and Cardiac Function by Tissue Doppler Imaging. The Copenhagen City Heart Study. Poster presented at AHA Scientific Sessions 2016, New Orleans, United States.
@conference{a524d45caa54429ea06a28804bbeb83d,
title = "Exercise and Cardiac Function by Tissue Doppler Imaging. The Copenhagen City Heart Study",
abstract = "Introduction: TDI (Tissue Doppler Imaging) is a sensitive marker of myocardial dysfunction and mortality in heart disease and in the general population. Regular physical activity is associated with risk reduction in coronary heart disease and mortality. There is a need for studies to clarify whether exercise has beneficial effects on cardiac function.Hypothesis: Regular physical exercise is associated with better cardiac function measured by TDI in the general populationMethods: 2,162 persons from the general population were examined by echocardiography and TDI. Peak systolic (s'), early diastolic (e') and late diastolic (a') velocities were measured by color TDI. Longitudinal displacement (LD) was calculated from the velocity curve during ejection. Statistical tests were performed by linear univariate and multivariable regression analyses, in relation to age groups (lt;50years, 50-65 years, gt;65 years) and physical activity level: I (inactivity), II (light activity), III (moderate activity) and IV (high-level activity). These levels were graded from the physical activity questionnaire, which contained information about activity level at work and in leisure time.Results: Participants agedlt;50 years had a significantly higher level of e' and LD in the most active group: e'=11.0 (textpm standard deviation, SD=2.0), plt;0.001; LD=12.8 (SD=2.1), plt;0.003. This pattern remained significant after adjusting for sex, hypertension, diabetes, and ischaemic heart disease and after Bonferroni correction. For e', there was significant interaction between age and activity level (plt;0.001), which supports the findings of better cardiac function with increasing activity among the young age group.Conclusion: In the general population, the association between increasing level of exercise and better cardiac function was found only in the youngest age group ( lt;50 years old). Among the elder age groups higher level of activity was not correlated to better cardiac function.Author Disclosures: G. Joseph: None. P. Sogaard: Other Research Support; Modest; GE Healthcare. G. Nielsen: None. T. Biering-Sorensen: None. P. Schnohr: None. J. Skov Jensen: None. R. Mogelvang: Other Research Support; Modest; GE Healthcare.",
author = "Gowsini Joseph and Peter Sogaard and Gitte Nielsen and Tor Biering-S{\o}rensen and Peter Schnohr and {Skov Jensen}, Jan and Rasmus M{\o}gelvang",
year = "2016",
language = "English",
note = "null ; Conference date: 12-11-2016 Through 16-11-2016",

}

Joseph, G, Sogaard, P, Nielsen, G, Biering-Sørensen, T, Schnohr, P, Skov Jensen, J & Møgelvang, R 2016, 'Exercise and Cardiac Function by Tissue Doppler Imaging. The Copenhagen City Heart Study', AHA Scientific Sessions 2016, New Orleans, United States, 12/11/2016 - 16/11/2016.

Exercise and Cardiac Function by Tissue Doppler Imaging. The Copenhagen City Heart Study. / Joseph, Gowsini; Sogaard, Peter; Nielsen, Gitte; Biering-Sørensen, Tor; Schnohr, Peter; Skov Jensen, Jan; Møgelvang, Rasmus.

2016. Poster presented at AHA Scientific Sessions 2016, New Orleans, United States.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

TY - CONF

T1 - Exercise and Cardiac Function by Tissue Doppler Imaging. The Copenhagen City Heart Study

AU - Joseph, Gowsini

AU - Sogaard, Peter

AU - Nielsen, Gitte

AU - Biering-Sørensen, Tor

AU - Schnohr, Peter

AU - Skov Jensen, Jan

AU - Møgelvang, Rasmus

PY - 2016

Y1 - 2016

N2 - Introduction: TDI (Tissue Doppler Imaging) is a sensitive marker of myocardial dysfunction and mortality in heart disease and in the general population. Regular physical activity is associated with risk reduction in coronary heart disease and mortality. There is a need for studies to clarify whether exercise has beneficial effects on cardiac function.Hypothesis: Regular physical exercise is associated with better cardiac function measured by TDI in the general populationMethods: 2,162 persons from the general population were examined by echocardiography and TDI. Peak systolic (s'), early diastolic (e') and late diastolic (a') velocities were measured by color TDI. Longitudinal displacement (LD) was calculated from the velocity curve during ejection. Statistical tests were performed by linear univariate and multivariable regression analyses, in relation to age groups (lt;50years, 50-65 years, gt;65 years) and physical activity level: I (inactivity), II (light activity), III (moderate activity) and IV (high-level activity). These levels were graded from the physical activity questionnaire, which contained information about activity level at work and in leisure time.Results: Participants agedlt;50 years had a significantly higher level of e' and LD in the most active group: e'=11.0 (textpm standard deviation, SD=2.0), plt;0.001; LD=12.8 (SD=2.1), plt;0.003. This pattern remained significant after adjusting for sex, hypertension, diabetes, and ischaemic heart disease and after Bonferroni correction. For e', there was significant interaction between age and activity level (plt;0.001), which supports the findings of better cardiac function with increasing activity among the young age group.Conclusion: In the general population, the association between increasing level of exercise and better cardiac function was found only in the youngest age group ( lt;50 years old). Among the elder age groups higher level of activity was not correlated to better cardiac function.Author Disclosures: G. Joseph: None. P. Sogaard: Other Research Support; Modest; GE Healthcare. G. Nielsen: None. T. Biering-Sorensen: None. P. Schnohr: None. J. Skov Jensen: None. R. Mogelvang: Other Research Support; Modest; GE Healthcare.

AB - Introduction: TDI (Tissue Doppler Imaging) is a sensitive marker of myocardial dysfunction and mortality in heart disease and in the general population. Regular physical activity is associated with risk reduction in coronary heart disease and mortality. There is a need for studies to clarify whether exercise has beneficial effects on cardiac function.Hypothesis: Regular physical exercise is associated with better cardiac function measured by TDI in the general populationMethods: 2,162 persons from the general population were examined by echocardiography and TDI. Peak systolic (s'), early diastolic (e') and late diastolic (a') velocities were measured by color TDI. Longitudinal displacement (LD) was calculated from the velocity curve during ejection. Statistical tests were performed by linear univariate and multivariable regression analyses, in relation to age groups (lt;50years, 50-65 years, gt;65 years) and physical activity level: I (inactivity), II (light activity), III (moderate activity) and IV (high-level activity). These levels were graded from the physical activity questionnaire, which contained information about activity level at work and in leisure time.Results: Participants agedlt;50 years had a significantly higher level of e' and LD in the most active group: e'=11.0 (textpm standard deviation, SD=2.0), plt;0.001; LD=12.8 (SD=2.1), plt;0.003. This pattern remained significant after adjusting for sex, hypertension, diabetes, and ischaemic heart disease and after Bonferroni correction. For e', there was significant interaction between age and activity level (plt;0.001), which supports the findings of better cardiac function with increasing activity among the young age group.Conclusion: In the general population, the association between increasing level of exercise and better cardiac function was found only in the youngest age group ( lt;50 years old). Among the elder age groups higher level of activity was not correlated to better cardiac function.Author Disclosures: G. Joseph: None. P. Sogaard: Other Research Support; Modest; GE Healthcare. G. Nielsen: None. T. Biering-Sorensen: None. P. Schnohr: None. J. Skov Jensen: None. R. Mogelvang: Other Research Support; Modest; GE Healthcare.

M3 - Poster

ER -

Joseph G, Sogaard P, Nielsen G, Biering-Sørensen T, Schnohr P, Skov Jensen J et al. Exercise and Cardiac Function by Tissue Doppler Imaging. The Copenhagen City Heart Study. 2016. Poster presented at AHA Scientific Sessions 2016, New Orleans, United States.