Gait alteration strategies for knee osteoarthritis: a comparison of joint loading via generic and patient-specific musculoskeletal model scaling techniques

Christine Mary Dzialo, Marco Mannisi, Kimmo Halonen, Mark de Zee, Jim Woodburn, Michael Skipper Andersen

Research output: Contribution to journalJournal articleResearchpeer-review

1 Citation (Scopus)
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Abstract

Gait modifications and laterally wedged insoles are non-invasive approaches used to treat medial compartment knee osteoarthritis. However, the outcome of these alterations is still a controversial topic. This study investigates how gait alteration techniques may have a unique effect on individual patients; and furthermore, the way we scale our musculoskeletal models to estimate the medial joint contact force may influence knee loading conditions. Five patients with clinical evidence of medial knee osteoarthritis were asked to walk at a normal walking speed over force plates and simultaneously 3D motion was captured during seven conditions (0°-, 5°-, 10°-insoles, shod, toe-in, toe-out, and wide stance). We developed patient-specific musculoskeletal models, using segmentations from magnetic resonance imaging to morph a generic model to patient-specific bone geometries and applied this morphing to estimate muscle insertion sites. Additionally, models were created of these patients using a simple linear scaling method. When examining the patients’ medial compartment contact force (peak and impulse) during stance phase, a ‘one-size-fits-all’ gait alteration aimed to reduce medial knee loading did not exist. Moreover, the different scaling methods lead to differences in medial contact forces; highlighting the importance of further investigation of musculoskeletal modeling methods prior to use in the clinical setting.

Original languageEnglish
JournalInternational Biomechanics
Volume6
Issue number1
Pages (from-to)54-65
Number of pages12
ISSN2333-5432
DOIs
Publication statusPublished - 21 Jul 2019

Keywords

  • Gait modifications
  • knee contact force
  • lateral insoles
  • magnetic resonance imaging
  • medial compartment knee osteoarthritis
  • morphing
  • musculoskeletal model
  • scaling

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