Graphical models for genetic analyses

Steffen Lilholt Lauritzen, Nuala A. Sheehan

Research output: Contribution to journalJournal articleResearchpeer-review

110 Citations (Scopus)

Abstract

This paper introduces graphical models as a natural environment in which to formulate and solve problems in genetics and related areas. Particular emphasis is given to the relationships among various local computation algorithms which have been developed within the hitherto mostly separate areas of graphical models and genetics. The potential of graphical models is explored and illustrated through a number of example applications where the genetic element is substantial or dominating.
Original languageEnglish
JournalStatistical Science
Volume18
Issue number4
Pages (from-to)489-514
ISSN0883-4237
Publication statusPublished - 2003

Keywords

  • local computation
  • linkage analysis
  • Bayesian network
  • QTL analysis
  • forensic genetics

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