Handling Oxygenation Targets in the Intensive Care Unit (HOT-ICU)-Protocol for a randomised clinical trial comparing a lower vs a higher oxygenation target in adults with acute hypoxaemic respiratory failure

Olav L Schjørring, Anders Perner, Jørn Wetterslev, Theis Lange, Frederik Keus, Jon H Laake, Marjatta Okkonen, Martin Siegemund, Matthew Morgan, Katrin M Thormar, Bodil S Rasmussen, and the HOT-ICU Investigators