Healthy Worms

Rikke Hindsgaul Harders, Katrine Vogt Møller, Maria Grymer Metz Mørch, Matthew S. Gill, Anders Olsen

Research output: Contribution to book/anthology/report/conference proceedingBook chapterResearchpeer-review

Abstract

HealthHealth is often seen as the attractive opposite to diseaseDisease but what are the molecular mechanisms that underpin health and can we target these pathways to improve healthHealth? Model organisms have been instrumental in defining the molecular genetics of complex biological processes, including longevityLongevity, and now they are increasingly being used to investigate healthHealth. In this chapter, we review some of the insights that have been gained by studying healthHealth and healthspanHealthspan in the soil nematode Caenorhabditis elegans. Interestingly, several gene mutations and interventions have been shown to improve healthHealth in C. elegansC. elegans offering possibilities of translation to humans.
Original languageEnglish
Title of host publicationExplaining Health Across the Sciences
EditorsJonathan Sholl, Suresh I.S. Rattan
Number of pages24
Place of PublicationCham
PublisherSpringer Publishing Company
Publication date2020
Edition1
Pages347-370
ISBN (Print)978-3-030-52662-7, 978-3-030-52665-8
ISBN (Electronic)978-3-030-52663-4
DOIs
Publication statusPublished - 2020
SeriesHealthy Ageing and Longevity
Volume12
ISSN2199-9007

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