In vivo charge injection limits increased after 'unsafe' stimulation

Suzan Meijs; Søren Sørensen; Kristian Rechendorff; Nico Rijkhoff

doi:10.5220/0005606301010105

In vivo charge injection limits increased after 'unsafe' stimulation

Suzan Meijs, Søren Sørensen, Kristian Rechendorff, Nico Rijkhoff

Research output: Contribution to book/anthology/report/conference proceeding › Article in proceeding › Research › peer-review

Abstract

The effect of unsafe stimulation on charge injection limits (Qinj) and pulsing capacitance (Cpulse) was investigated. Four stimulation protocols were applied: 20 mA – 200 and 400 Hz, 50 mA – 200 and 400 Hz. Increasing Qinj and Cpulse were observed for all stimulation protocols. Corrosion was not observed with any of the stimulation protocols and no tissue damage was observed for the 20 mA – 200 Hz stimulation group. This indicates that the ‘safe potential window’ may not be applicable in vivo, as no damage was done stimulating with 20 mA at 200 Hz, while damage was done using the same current at 400 Hz.

Original language	English
Title of host publication	Proceedings of the 3rd International Congress on Neurotechnology, Electronics and Informatics, NEUROTECHNIX 2015, 16-17 November 2015, Lisbon, Portugal
Publisher	SCITEPRESS Digital Library
Publication date	2015
Pages	101-105
ISBN (Print)	978-989-758-161-8
DOIs	https://doi.org/10.5220/0005606301010105
Publication status	Published - 2015
Event	International Congress on Neurotechnology, Electronics and Informatics, NEUROTECHNIX - Lisbon, Portugal Duration: 16 Nov 2015 → 17 Nov 2015 Conference number: 3

Conference

Conference	International Congress on Neurotechnology, Electronics and Informatics, NEUROTECHNIX
Number	3
Country/Territory	Portugal
City	Lisbon
Period	16/11/2015 → 17/11/2015

Access to Document

10.5220/0005606301010105

http://www.scitepress.org/Portal/PublicationsDetail.aspx?ID=6BhEoeUMvSY=&t=1

AUB Link

Search for the material in Aalborg University Library's search engine

Cite this

Meijs, S., Sørensen, S., Rechendorff, K., & Rijkhoff, N. (2015). In vivo charge injection limits increased after 'unsafe' stimulation. In Proceedings of the 3rd International Congress on Neurotechnology, Electronics and Informatics, NEUROTECHNIX 2015, 16-17 November 2015, Lisbon, Portugal (pp. 101-105). SCITEPRESS Digital Library. https://doi.org/10.5220/0005606301010105

@inproceedings{34e704826f564ce7b1a59d5d3f1cb322,

title = "In vivo charge injection limits increased after 'unsafe' stimulation",

abstract = "The effect of unsafe stimulation on charge injection limits (Qinj) and pulsing capacitance (Cpulse) was investigated. Four stimulation protocols were applied: 20 mA – 200 and 400 Hz, 50 mA – 200 and 400 Hz. Increasing Qinj and Cpulse were observed for all stimulation protocols. Corrosion was not observed with any of the stimulation protocols and no tissue damage was observed for the 20 mA – 200 Hz stimulation group. This indicates that the {\textquoteleft}safe potential window{\textquoteright} may not be applicable in vivo, as no damage was done stimulating with 20 mA at 200 Hz, while damage was done using the same current at 400 Hz.",

author = "Suzan Meijs and S{\o}ren S{\o}rensen and Kristian Rechendorff and Nico Rijkhoff",

year = "2015",

doi = "10.5220/0005606301010105",

language = "English",

isbn = "978-989-758-161-8",

pages = "101--105",

booktitle = "Proceedings of the 3rd International Congress on Neurotechnology, Electronics and Informatics, NEUROTECHNIX 2015, 16-17 November 2015, Lisbon, Portugal",

publisher = "SCITEPRESS Digital Library",

note = "International Congress on Neurotechnology, Electronics and Informatics, NEUROTECHNIX ; Conference date: 16-11-2015 Through 17-11-2015",

}

Meijs, S, Sørensen, S, Rechendorff, K & Rijkhoff, N 2015, In vivo charge injection limits increased after 'unsafe' stimulation. in Proceedings of the 3rd International Congress on Neurotechnology, Electronics and Informatics, NEUROTECHNIX 2015, 16-17 November 2015, Lisbon, Portugal. SCITEPRESS Digital Library, pp. 101-105, International Congress on Neurotechnology, Electronics and Informatics, NEUROTECHNIX, Lisbon, Portugal, 16/11/2015. https://doi.org/10.5220/0005606301010105

In vivo charge injection limits increased after 'unsafe' stimulation. / Meijs, Suzan; Sørensen, Søren; Rechendorff, Kristian et al.
Proceedings of the 3rd International Congress on Neurotechnology, Electronics and Informatics, NEUROTECHNIX 2015, 16-17 November 2015, Lisbon, Portugal. SCITEPRESS Digital Library, 2015. p. 101-105.

Research output: Contribution to book/anthology/report/conference proceeding › Article in proceeding › Research › peer-review

TY - GEN

T1 - In vivo charge injection limits increased after 'unsafe' stimulation

AU - Meijs, Suzan

AU - Sørensen, Søren

AU - Rechendorff, Kristian

AU - Rijkhoff, Nico

N1 - Conference code: 3

PY - 2015

Y1 - 2015

N2 - The effect of unsafe stimulation on charge injection limits (Qinj) and pulsing capacitance (Cpulse) was investigated. Four stimulation protocols were applied: 20 mA – 200 and 400 Hz, 50 mA – 200 and 400 Hz. Increasing Qinj and Cpulse were observed for all stimulation protocols. Corrosion was not observed with any of the stimulation protocols and no tissue damage was observed for the 20 mA – 200 Hz stimulation group. This indicates that the ‘safe potential window’ may not be applicable in vivo, as no damage was done stimulating with 20 mA at 200 Hz, while damage was done using the same current at 400 Hz.

AB - The effect of unsafe stimulation on charge injection limits (Qinj) and pulsing capacitance (Cpulse) was investigated. Four stimulation protocols were applied: 20 mA – 200 and 400 Hz, 50 mA – 200 and 400 Hz. Increasing Qinj and Cpulse were observed for all stimulation protocols. Corrosion was not observed with any of the stimulation protocols and no tissue damage was observed for the 20 mA – 200 Hz stimulation group. This indicates that the ‘safe potential window’ may not be applicable in vivo, as no damage was done stimulating with 20 mA at 200 Hz, while damage was done using the same current at 400 Hz.

U2 - 10.5220/0005606301010105

DO - 10.5220/0005606301010105

M3 - Article in proceeding

SN - 978-989-758-161-8

SP - 101

EP - 105

BT - Proceedings of the 3rd International Congress on Neurotechnology, Electronics and Informatics, NEUROTECHNIX 2015, 16-17 November 2015, Lisbon, Portugal

PB - SCITEPRESS Digital Library

T2 - International Congress on Neurotechnology, Electronics and Informatics, NEUROTECHNIX

Y2 - 16 November 2015 through 17 November 2015

ER -

In vivo charge injection limits increased after 'unsafe' stimulation

Abstract

Conference

Access to Document

AUB Link

Fingerprint

Cite this