Impact of hydrochloric acid instillation on salvage of infected central venous catheters in children with acute lymphoblastic leukaemia

Mette Madsen; Steen Rosthøj

doi:10.3109/00365548.2012.708941

Impact of hydrochloric acid instillation on salvage of infected central venous catheters in children with acute lymphoblastic leukaemia

Mette Madsen, Steen Rosthøj

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

Abstract

Bacteraemia associated with indwelling central venous catheters (CVC) causes significant morbidity in children with cancer. Hydrochloric acid (HCl) instillations have been reported to salvage CVCs with antibiotic-refractory infection. We implemented this treatment in 2002. The impact on the survival of CVCs has been evaluated in a retrospective cohort study of children with acute lymphoblastic leukaemia (ALL).

Original language	English
Journal	Scandinavian Journal of Infectious Diseases
Volume	45
Issue number	1
Pages (from-to)	38-44
Number of pages	7
ISSN	0036-5548
DOIs	https://doi.org/10.3109/00365548.2012.708941
Publication status	Published - Jan 2013

Keywords

Adolescent
Bacteremia
Catheter-Related Infections
Catheterization, Central Venous
Central Venous Catheters
Child
Child, Preschool
Female
Humans
Hydrochloric Acid
Infant
Kaplan-Meier Estimate
Male
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Retrospective Studies

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title = "Impact of hydrochloric acid instillation on salvage of infected central venous catheters in children with acute lymphoblastic leukaemia",

abstract = "Bacteraemia associated with indwelling central venous catheters (CVC) causes significant morbidity in children with cancer. Hydrochloric acid (HCl) instillations have been reported to salvage CVCs with antibiotic-refractory infection. We implemented this treatment in 2002. The impact on the survival of CVCs has been evaluated in a retrospective cohort study of children with acute lymphoblastic leukaemia (ALL).",

keywords = "Adolescent, Bacteremia, Catheter-Related Infections, Catheterization, Central Venous, Central Venous Catheters, Child, Child, Preschool, Female, Humans, Hydrochloric Acid, Infant, Kaplan-Meier Estimate, Male, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Retrospective Studies",

author = "Mette Madsen and Steen Rosth{\o}j",

year = "2013",

month = jan,

doi = "10.3109/00365548.2012.708941",

language = "English",

volume = "45",

pages = "38--44",

journal = "Scandinavian Journal of Infectious Diseases",

issn = "0036-5548",

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TY - JOUR

T1 - Impact of hydrochloric acid instillation on salvage of infected central venous catheters in children with acute lymphoblastic leukaemia

AU - Madsen, Mette

AU - Rosthøj, Steen

PY - 2013/1

Y1 - 2013/1

N2 - Bacteraemia associated with indwelling central venous catheters (CVC) causes significant morbidity in children with cancer. Hydrochloric acid (HCl) instillations have been reported to salvage CVCs with antibiotic-refractory infection. We implemented this treatment in 2002. The impact on the survival of CVCs has been evaluated in a retrospective cohort study of children with acute lymphoblastic leukaemia (ALL).

AB - Bacteraemia associated with indwelling central venous catheters (CVC) causes significant morbidity in children with cancer. Hydrochloric acid (HCl) instillations have been reported to salvage CVCs with antibiotic-refractory infection. We implemented this treatment in 2002. The impact on the survival of CVCs has been evaluated in a retrospective cohort study of children with acute lymphoblastic leukaemia (ALL).

KW - Adolescent

KW - Bacteremia

KW - Catheter-Related Infections

KW - Catheterization, Central Venous

KW - Central Venous Catheters

KW - Child

KW - Child, Preschool

KW - Female

KW - Humans

KW - Hydrochloric Acid

KW - Infant

KW - Kaplan-Meier Estimate

KW - Male

KW - Precursor Cell Lymphoblastic Leukemia-Lymphoma

KW - Retrospective Studies

U2 - 10.3109/00365548.2012.708941

DO - 10.3109/00365548.2012.708941

M3 - Journal article

C2 - 22992112

SN - 0036-5548

VL - 45

SP - 38

EP - 44

JO - Scandinavian Journal of Infectious Diseases

JF - Scandinavian Journal of Infectious Diseases

IS - 1

ER -

Impact of hydrochloric acid instillation on salvage of infected central venous catheters in children with acute lymphoblastic leukaemia

Abstract

Keywords

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