Impact of percutaneous intervention compared to pharmaceutical therapy on complex arrhythmias in patients with chronic total coronary occlusion. Rationale and design of the CTO-ARRHYTHMIA study

Martin Kirk Christensen; Ashkan Eftekhari; Bent Raungaard; Terje Kristian Steigen; Indulis Kumsaars; Sam Riahi; Peter Søgaard; Leif Thuesen

doi:10.1016/j.carrev.2023.04.001

Impact of percutaneous intervention compared to pharmaceutical therapy on complex arrhythmias in patients with chronic total coronary occlusion. Rationale and design of the CTO-ARRHYTHMIA study

Martin Kirk Christensen^*, Ashkan Eftekhari, Bent Raungaard, Terje Kristian Steigen, Indulis Kumsaars, Sam Riahi, Peter Søgaard, Leif Thuesen

^*Corresponding author for this work

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Abstract

Chronic total coronary occlusions (CTO) occur in up to 50 % of patients with coronary artery disease by angiography. In CTO-patients, clinically significant arrhythmia is potentially important and insufficiently investigated. Therefore, the purpose of the CTO-ARRHYTHMIA study was to investigate the incidence of loop recorder detected clinically significant arrhythmias and the effect on arrhythmias of revascularization by CTO-PCI. The study is an independent sub-study of the NOrdic-Baltic Randomized Registry Study for Evaluation of PCI in Chronic Total Coronary Occlusion (NOBLE-CTO); ClinicalTrials.gov Identifier NCT03392415. NOBLE-CTO prospectively collects procedural data, quality of life measures, echocardiographic and cardiac MRI findings before and after treatment as well as clinical outcomes in all CTO patients that may be treated by PCI.

Original language	English
Journal	Cardiovascular Revascularization Medicine
Volume	54
Pages (from-to)	69-72
Number of pages	4
ISSN	1553-8389
DOIs	https://doi.org/10.1016/j.carrev.2023.04.001
Publication status	Published - Sept 2023

Bibliographical note

Keywords

Arrhythmias
CTO
Chronic total occlusion
Ventricular tachycardia

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Christensen, M. K., Eftekhari, A., Raungaard, B., Steigen, T. K., Kumsaars, I., Riahi, S., Søgaard, P., & Thuesen, L. (2023). Impact of percutaneous intervention compared to pharmaceutical therapy on complex arrhythmias in patients with chronic total coronary occlusion. Rationale and design of the CTO-ARRHYTHMIA study. Cardiovascular Revascularization Medicine, 54, 69-72. Advance online publication. https://doi.org/10.1016/j.carrev.2023.04.001

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title = "Impact of percutaneous intervention compared to pharmaceutical therapy on complex arrhythmias in patients with chronic total coronary occlusion. Rationale and design of the CTO-ARRHYTHMIA study",

abstract = "Chronic total coronary occlusions (CTO) occur in up to 50 % of patients with coronary artery disease by angiography. In CTO-patients, clinically significant arrhythmia is potentially important and insufficiently investigated. Therefore, the purpose of the CTO-ARRHYTHMIA study was to investigate the incidence of loop recorder detected clinically significant arrhythmias and the effect on arrhythmias of revascularization by CTO-PCI. The study is an independent sub-study of the NOrdic-Baltic Randomized Registry Study for Evaluation of PCI in Chronic Total Coronary Occlusion (NOBLE-CTO); ClinicalTrials.gov Identifier NCT03392415. NOBLE-CTO prospectively collects procedural data, quality of life measures, echocardiographic and cardiac MRI findings before and after treatment as well as clinical outcomes in all CTO patients that may be treated by PCI.",

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author = "Christensen, {Martin Kirk} and Ashkan Eftekhari and Bent Raungaard and Steigen, {Terje Kristian} and Indulis Kumsaars and Sam Riahi and Peter S{\o}gaard and Leif Thuesen",

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Christensen, MK , Eftekhari, A , Raungaard, B, Steigen, TK, Kumsaars, I, Riahi, S , Søgaard, P & Thuesen, L 2023, 'Impact of percutaneous intervention compared to pharmaceutical therapy on complex arrhythmias in patients with chronic total coronary occlusion. Rationale and design of the CTO-ARRHYTHMIA study', Cardiovascular Revascularization Medicine, vol. 54, pp. 69-72. https://doi.org/10.1016/j.carrev.2023.04.001

Impact of percutaneous intervention compared to pharmaceutical therapy on complex arrhythmias in patients with chronic total coronary occlusion. Rationale and design of the CTO-ARRHYTHMIA study. / Christensen, Martin Kirk ; Eftekhari, Ashkan ; Raungaard, Bent et al.
In: Cardiovascular Revascularization Medicine, Vol. 54, 09.2023, p. 69-72.

Research output: Contribution to journal › Journal article › Research › peer-review

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AU - Raungaard, Bent

AU - Steigen, Terje Kristian

AU - Kumsaars, Indulis

AU - Riahi, Sam

AU - Søgaard, Peter

AU - Thuesen, Leif

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AB - Chronic total coronary occlusions (CTO) occur in up to 50 % of patients with coronary artery disease by angiography. In CTO-patients, clinically significant arrhythmia is potentially important and insufficiently investigated. Therefore, the purpose of the CTO-ARRHYTHMIA study was to investigate the incidence of loop recorder detected clinically significant arrhythmias and the effect on arrhythmias of revascularization by CTO-PCI. The study is an independent sub-study of the NOrdic-Baltic Randomized Registry Study for Evaluation of PCI in Chronic Total Coronary Occlusion (NOBLE-CTO); ClinicalTrials.gov Identifier NCT03392415. NOBLE-CTO prospectively collects procedural data, quality of life measures, echocardiographic and cardiac MRI findings before and after treatment as well as clinical outcomes in all CTO patients that may be treated by PCI.

KW - Arrhythmias

KW - CTO

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DO - 10.1016/j.carrev.2023.04.001

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ER -

Christensen MK , Eftekhari A , Raungaard B, Steigen TK, Kumsaars I, Riahi S et al. Impact of percutaneous intervention compared to pharmaceutical therapy on complex arrhythmias in patients with chronic total coronary occlusion. Rationale and design of the CTO-ARRHYTHMIA study. Cardiovascular Revascularization Medicine. 2023 Sept;54:69-72. Epub 2023 Apr 10. doi: 10.1016/j.carrev.2023.04.001

Impact of percutaneous intervention compared to pharmaceutical therapy on complex arrhythmias in patients with chronic total coronary occlusion. Rationale and design of the CTO-ARRHYTHMIA study

Abstract

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Keywords

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