Abstract
The in vitro susceptibility of recent Danish human clinical isolates of Campylobacter pyloridis to cimetidine, sucralfate, bismuth subsalicylate and sixteen antimicrobial agents was determined by an agar-dilution technique. Benzylpenicillin was the most active drug (MIC90 = 0.1 microgram/ml); ampicillin, erythromycin, gentamicin and ciprofloxacin were slightly less active. All strains were resistant to 100 micrograms sulfamethizole, and nalidixic acid also had little activity on weight basis. Of the three anti-peptic ulcer drugs, bismuth subsalicylate was most active (MIC90 25 micrograms/ml), but sucralfate and cimetidine also had antibacterial activity, although only little (MIC90 3200 micrograms/ml).
Original language | English |
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Journal | Acta pathologica, microbiologica, et immunologica Scandinavica. Section B, Microbiology |
Volume | 95 |
Issue number | 2 |
Pages (from-to) | 147-9 |
Number of pages | 3 |
ISSN | 0108-0180 |
Publication status | Published - Apr 1987 |
Externally published | Yes |
Keywords
- Anti-Bacterial Agents
- Bismuth
- Campylobacter
- Cimetidine
- Humans
- Microbial Sensitivity Tests
- Organometallic Compounds
- Salicylates
- Sucralfate