Late lumen loss and intima hyperplasia after sirolimus-eluting and zotarolimus-eluting stent implantation in diabetic patients: the diabetes and drug-eluting stent (DiabeDES III) angiography and intravascular ultrasound trial

Lisette Okkels Jensen; Michael Mæng; Per Thayssen; Anton Boel Villadsen; Lars Romer Krusell; Hans Erik Botker; Knud Erik Pedersen; Jens Aaroe; Evald Høj Christiansen; Thomas Vesterlund; Knud Noerregaard Hansen; Jan Ravkilde; Hans-Henrik Tilsted Hansen; Jens Flensted Lassen; Leif Thuesen

doi:10.4244/EIJV7I3A56

Late lumen loss and intima hyperplasia after sirolimus-eluting and zotarolimus-eluting stent implantation in diabetic patients: the diabetes and drug-eluting stent (DiabeDES III) angiography and intravascular ultrasound trial

Lisette Okkels Jensen, Michael Mæng, Per Thayssen, Anton Boel Villadsen, Lars Romer Krusell, Hans Erik Botker, Knud Erik Pedersen, Jens Aaroe, Evald Høj Christiansen, Thomas Vesterlund, Knud Noerregaard Hansen, Jan Ravkilde, Hans-Henrik Tilsted Hansen, Jens Flensted Lassen, Leif Thuesen

Research output: Contribution to journal › Journal article › Research › peer-review

23 Citations (Scopus)

Abstract

Patients with diabetes mellitus have increased risk of in-stent restenosis after coronary stent implantation due to neointimal hyperplasia (NIH). The aim of this study was to use quantitative coronary angiography (QCA) and volumetric intravascular ultrasound (IVUS) to evaluate the effects of the sirolimus-eluting Cypher® stent (SES) and the zotarolimus-eluting Endeavor® stent (ZES) on angiographic late lumen loss and intima hyperplasia in diabetic patients.

Original language	English
Volume	7
Pages (from-to)	323-31
Number of pages	9
ISSN	1774-024X
DOIs	https://doi.org/10.4244/EIJV7I3A56
Publication status	Published - 2011
Externally published	Yes

Keywords

Aged
Angioplasty, Balloon, Laser-Assisted
Coronary Angiography
Coronary Artery Disease
Coronary Restenosis
Diabetes Complications
Drug-Eluting Stents
Female
Follow-Up Studies
Humans
Hyperplasia
Male
Middle Aged
Neointima
Risk Factors
Single-Blind Method
Sirolimus
Treatment Outcome
Ultrasonography, Interventional

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Jensen, L. O., Mæng, M., Thayssen, P., Boel Villadsen, A., Krusell, L. R., Botker, H. E., Pedersen, K. E., Aaroe, J., Christiansen, E. H., Vesterlund, T., Hansen, K. N., Ravkilde, J., Hansen, H-H. T., Lassen, J. F., & Thuesen, L. (2011). Late lumen loss and intima hyperplasia after sirolimus-eluting and zotarolimus-eluting stent implantation in diabetic patients: the diabetes and drug-eluting stent (DiabeDES III) angiography and intravascular ultrasound trial. 7, 323-31. https://doi.org/10.4244/EIJV7I3A56

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title = "Late lumen loss and intima hyperplasia after sirolimus-eluting and zotarolimus-eluting stent implantation in diabetic patients: the diabetes and drug-eluting stent (DiabeDES III) angiography and intravascular ultrasound trial",

abstract = "Patients with diabetes mellitus have increased risk of in-stent restenosis after coronary stent implantation due to neointimal hyperplasia (NIH). The aim of this study was to use quantitative coronary angiography (QCA) and volumetric intravascular ultrasound (IVUS) to evaluate the effects of the sirolimus-eluting Cypher{\textregistered} stent (SES) and the zotarolimus-eluting Endeavor{\textregistered} stent (ZES) on angiographic late lumen loss and intima hyperplasia in diabetic patients.",

keywords = "Aged, Angioplasty, Balloon, Laser-Assisted, Coronary Angiography, Coronary Artery Disease, Coronary Restenosis, Diabetes Complications, Drug-Eluting Stents, Female, Follow-Up Studies, Humans, Hyperplasia, Male, Middle Aged, Neointima, Risk Factors, Single-Blind Method, Sirolimus, Treatment Outcome, Ultrasonography, Interventional",

author = "Jensen, {Lisette Okkels} and Michael M{\ae}ng and Per Thayssen and {Boel Villadsen}, Anton and Krusell, {Lars Romer} and Botker, {Hans Erik} and Pedersen, {Knud Erik} and Jens Aaroe and Christiansen, {Evald H{\o}j} and Thomas Vesterlund and Hansen, {Knud Noerregaard} and Jan Ravkilde and Hansen, {Hans-Henrik Tilsted} and Lassen, {Jens Flensted} and Leif Thuesen",

year = "2011",

doi = "10.4244/EIJV7I3A56",

language = "English",

volume = "7",

pages = "323--31",

issn = "1774-024X",

publisher = "Europa Digital & Publishing",

}

Jensen, LO, Mæng, M, Thayssen, P, Boel Villadsen, A, Krusell, LR, Botker, HE, Pedersen, KE, Aaroe, J, Christiansen, EH, Vesterlund, T, Hansen, KN, Ravkilde, J, Hansen, H-HT, Lassen, JF & Thuesen, L 2011, 'Late lumen loss and intima hyperplasia after sirolimus-eluting and zotarolimus-eluting stent implantation in diabetic patients: the diabetes and drug-eluting stent (DiabeDES III) angiography and intravascular ultrasound trial', vol. 7, pp. 323-31. https://doi.org/10.4244/EIJV7I3A56

Late lumen loss and intima hyperplasia after sirolimus-eluting and zotarolimus-eluting stent implantation in diabetic patients: the diabetes and drug-eluting stent (DiabeDES III) angiography and intravascular ultrasound trial. / Jensen, Lisette Okkels; Mæng, Michael; Thayssen, Per et al.
Vol. 7, 2011, p. 323-31.

Research output: Contribution to journal › Journal article › Research › peer-review

TY - JOUR

T1 - Late lumen loss and intima hyperplasia after sirolimus-eluting and zotarolimus-eluting stent implantation in diabetic patients: the diabetes and drug-eluting stent (DiabeDES III) angiography and intravascular ultrasound trial

AU - Jensen, Lisette Okkels

AU - Mæng, Michael

AU - Thayssen, Per

AU - Boel Villadsen, Anton

AU - Krusell, Lars Romer

AU - Botker, Hans Erik

AU - Pedersen, Knud Erik

AU - Aaroe, Jens

AU - Christiansen, Evald Høj

AU - Vesterlund, Thomas

AU - Hansen, Knud Noerregaard

AU - Ravkilde, Jan

AU - Hansen, Hans-Henrik Tilsted

AU - Lassen, Jens Flensted

AU - Thuesen, Leif

PY - 2011

Y1 - 2011

N2 - Patients with diabetes mellitus have increased risk of in-stent restenosis after coronary stent implantation due to neointimal hyperplasia (NIH). The aim of this study was to use quantitative coronary angiography (QCA) and volumetric intravascular ultrasound (IVUS) to evaluate the effects of the sirolimus-eluting Cypher® stent (SES) and the zotarolimus-eluting Endeavor® stent (ZES) on angiographic late lumen loss and intima hyperplasia in diabetic patients.

AB - Patients with diabetes mellitus have increased risk of in-stent restenosis after coronary stent implantation due to neointimal hyperplasia (NIH). The aim of this study was to use quantitative coronary angiography (QCA) and volumetric intravascular ultrasound (IVUS) to evaluate the effects of the sirolimus-eluting Cypher® stent (SES) and the zotarolimus-eluting Endeavor® stent (ZES) on angiographic late lumen loss and intima hyperplasia in diabetic patients.

KW - Aged

KW - Angioplasty, Balloon, Laser-Assisted

KW - Coronary Angiography

KW - Coronary Artery Disease

KW - Coronary Restenosis

KW - Diabetes Complications

KW - Drug-Eluting Stents

KW - Female

KW - Follow-Up Studies

KW - Humans

KW - Hyperplasia

KW - Male

KW - Middle Aged

KW - Neointima

KW - Risk Factors

KW - Single-Blind Method

KW - Sirolimus

KW - Treatment Outcome

KW - Ultrasonography, Interventional

U2 - 10.4244/EIJV7I3A56

DO - 10.4244/EIJV7I3A56

M3 - Journal article

SN - 1774-024X

VL - 7

SP - 323

EP - 331

ER -