Abstract
Phrenic nerve stimulation is a major obstacle in cardiac resynchronization therapy (CRT). Activation characteristics of the heart and phrenic nerve are different with higher chronaxie for the heart. Therefore, longer pulse durations could be beneficial in preventing phrenic nerve stimulation during CRT due to a decreased threshold for the heart compared to the phrenic nerve. We investigated if long pulse durations decreased left ventricular (LV) thresholds relatively to phrenic nerve thresholds in humans.
| Original language | English |
|---|---|
| Journal | Journal of Cardiovascular Electrophysiology |
| Volume | 25 |
| Issue number | 5 |
| Pages (from-to) | 485-490 |
| Number of pages | 6 |
| ISSN | 1045-3873 |
| DOIs | |
| Publication status | Published - 2014 |
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