LPV Based Control of Glucose Concentration in Type 2 Diabetes

Deividas Eringis; Peter Aurelius Munk; Benjamin Keldberg Andersen; Rahul Sylvester Suresh; John Leth

doi:10.1016/j.ifacol.2020.12.675

LPV Based Control of Glucose Concentration in Type 2 Diabetes

Deividas Eringis, Peter Aurelius Munk, Benjamin Keldberg Andersen, Rahul Sylvester Suresh, John Leth

Research output: Contribution to journal › Conference article in Journal › Research › peer-review

3 Citations (Scopus)

Abstract

This paper investigates continuous-time LPV dynamic-output feedback for controlling a type 2 diabetes patients' fasting glucose concentration. To emulate a real life scenario, the input and measurement were specified only once per day, and biological variance was introduced. The results were evaluated by examining the settling time, variance after settling, and the violation of the nominal fasting glucose concentration range of 4 - 5 [mmol/l]. The LPV dynamic-output feedback controller was compared to a simple rule based titration algorithm and a PI controller tuned by LPV methods. The LPV dynamic-output feedback controller, proved to deliver better results, in particular for the transient period.

Original language	English
Book series	IFAC-PapersOnLine
Volume	53
Issue number	2
Pages (from-to)	16386-16393
Number of pages	8
ISSN	2405-8963
DOIs	https://doi.org/10.1016/j.ifacol.2020.12.675
Publication status	Published - 2020
Event	21st IFAC World Congress 2020 - Berlin, Germany Duration: 12 Jul 2020 → 17 Jul 2020

Conference

Conference	21st IFAC World Congress 2020
Country/Territory	Germany
City	Berlin
Period	12/07/2020 → 17/07/2020

Bibliographical note

Publisher Copyright:
© 2020 Elsevier B.V.. All rights reserved.

Keywords

Diabetes
LPV control
Type 2 Diabetes

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title = "LPV Based Control of Glucose Concentration in Type 2 Diabetes",

abstract = "This paper investigates continuous-time LPV dynamic-output feedback for controlling a type 2 diabetes patients' fasting glucose concentration. To emulate a real life scenario, the input and measurement were specified only once per day, and biological variance was introduced. The results were evaluated by examining the settling time, variance after settling, and the violation of the nominal fasting glucose concentration range of 4 - 5 [mmol/l]. The LPV dynamic-output feedback controller was compared to a simple rule based titration algorithm and a PI controller tuned by LPV methods. The LPV dynamic-output feedback controller, proved to deliver better results, in particular for the transient period.",

keywords = "Diabetes, LPV control, Type 2 Diabetes",

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AU - Andersen, Benjamin Keldberg

AU - Suresh, Rahul Sylvester

AU - Leth, John

PY - 2020

Y1 - 2020

N2 - This paper investigates continuous-time LPV dynamic-output feedback for controlling a type 2 diabetes patients' fasting glucose concentration. To emulate a real life scenario, the input and measurement were specified only once per day, and biological variance was introduced. The results were evaluated by examining the settling time, variance after settling, and the violation of the nominal fasting glucose concentration range of 4 - 5 [mmol/l]. The LPV dynamic-output feedback controller was compared to a simple rule based titration algorithm and a PI controller tuned by LPV methods. The LPV dynamic-output feedback controller, proved to deliver better results, in particular for the transient period.

AB - This paper investigates continuous-time LPV dynamic-output feedback for controlling a type 2 diabetes patients' fasting glucose concentration. To emulate a real life scenario, the input and measurement were specified only once per day, and biological variance was introduced. The results were evaluated by examining the settling time, variance after settling, and the violation of the nominal fasting glucose concentration range of 4 - 5 [mmol/l]. The LPV dynamic-output feedback controller was compared to a simple rule based titration algorithm and a PI controller tuned by LPV methods. The LPV dynamic-output feedback controller, proved to deliver better results, in particular for the transient period.

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KW - LPV control

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M3 - Conference article in Journal

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VL - 53

SP - 16386

EP - 16393

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JF - IFAC-PapersOnLine

IS - 2

T2 - 21st IFAC World Congress 2020

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ER -

LPV Based Control of Glucose Concentration in Type 2 Diabetes

Abstract

Conference

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Keywords

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