Management of Endocrine Disease: Diabetes and osteoporosis: cause for concern?

Jakob Starup-Linde, Peter Vestergaard

Research output: Contribution to journalReview articlepeer-review

54 Citations (Scopus)

Abstract

Diabetes and osteoporosis are both frequent conditions, and they may thus occur simultaneously by chance. However, a growing body of evidence suggests that hyperglycemia may impair bone matrix formation and biochemical competence. Decreased biomechanical competence may be present even in a setting of increased bone mineral density, as assessed by traditional dual energy X-ray absorptiometry or normal structural parameters by quantitative computed tomography. Also, the absence of endogenous insulin secretion in type 1 diabetes (T1D) and insulin resistance or, in some cases, frank hyperinsulinemia in T2D may play a role.

Original languageEnglish
JournalEuropean Journal of Endocrinology
Volume173
Issue number3
Pages (from-to)R93-99
Number of pages7
ISSN0804-4643
DOIs
Publication statusPublished - Sept 2015

Bibliographical note

This article has been found as a 'Free Version' from the Publisher on July 26th 2018. When the access to the article closes, please notify vbn@aub.aau.dk”

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