Metabolic engineering of Aspergillus niger via ribonucleoprotein-based CRISPR–Cas9 system for succinic acid production from renewable biomass

Lei Yang; Mikkel Møller Henriksen; Rasmus Syrach Hansen; Mette Lübeck; Jesper Vang; Julie Egelund Andersen; Signe Bille; Peter Stephensen Lübeck

doi:10.1186/s13068-020-01850-5

Metabolic engineering of Aspergillus niger via ribonucleoprotein-based CRISPR–Cas9 system for succinic acid production from renewable biomass

Lei Yang^*, Mikkel Møller Henriksen, Rasmus Syrach Hansen, Mette Lübeck, Jesper Vang, Julie Egelund Andersen, Signe Bille, Peter Stephensen Lübeck

^*Corresponding author

Research output: Contribution to journal › Journal article › Research › peer-review

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Original language	English
Article number	206
Journal	Biotechnology for Biofuels
Volume	13
Issue number	1
ISSN	1754-6834
DOIs	https://doi.org/10.1186/s13068-020-01850-5
Publication status	Published - Dec 2020

Keywords

Aspergillus niger
CRISPR–Cas9 system
Metabolic engineering
Succinic acid production

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10.1186/s13068-020-01850-5

s13068-020-01850-5Final published version, 1.71 MBLicence: CC BY 4.0

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@article{14f832a6cee74a2491b0709f80b5f312,

title = "Metabolic engineering of Aspergillus niger via ribonucleoprotein-based CRISPR–Cas9 system for succinic acid production from renewable biomass",

keywords = "Aspergillus niger, CRISPR–Cas9 system, Metabolic engineering, Succinic acid production",

author = "Lei Yang and Henriksen, {Mikkel M{\o}ller} and Hansen, {Rasmus Syrach} and Mette L{\"u}beck and Jesper Vang and Andersen, {Julie Egelund} and Signe Bille and L{\"u}beck, {Peter Stephensen}",

note = "Funding Information: Financial support from the Danish Strategic Research Program MycoFuelChem (DSF Grant No. 11-116803) is acknowledged. Publisher Copyright: {\textcopyright} 2020, The Author(s). Copyright: Copyright 2020 Elsevier B.V., All rights reserved.",

year = "2020",

month = dec,

doi = "10.1186/s13068-020-01850-5",

language = "English",

volume = "13",

journal = "Biotechnology for Biofuels",

issn = "1754-6834",

publisher = "BioMed Central",

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Metabolic engineering of Aspergillus niger via ribonucleoprotein-based CRISPR–Cas9 system for succinic acid production from renewable biomass. / Yang, Lei; Henriksen, Mikkel Møller; Hansen, Rasmus Syrach; Lübeck, Mette; Vang, Jesper; Andersen, Julie Egelund; Bille, Signe; Lübeck, Peter Stephensen.

In: Biotechnology for Biofuels, Vol. 13, No. 1, 206, 12.2020.

Research output: Contribution to journal › Journal article › Research › peer-review

TY - JOUR

T1 - Metabolic engineering of Aspergillus niger via ribonucleoprotein-based CRISPR–Cas9 system for succinic acid production from renewable biomass

AU - Yang, Lei

AU - Henriksen, Mikkel Møller

AU - Hansen, Rasmus Syrach

AU - Lübeck, Mette

AU - Vang, Jesper

AU - Andersen, Julie Egelund

AU - Bille, Signe

AU - Lübeck, Peter Stephensen

N1 - Funding Information: Financial support from the Danish Strategic Research Program MycoFuelChem (DSF Grant No. 11-116803) is acknowledged. Publisher Copyright: © 2020, The Author(s). Copyright: Copyright 2020 Elsevier B.V., All rights reserved.

PY - 2020/12

Y1 - 2020/12

KW - Aspergillus niger

KW - CRISPR–Cas9 system

KW - Metabolic engineering

KW - Succinic acid production

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U2 - 10.1186/s13068-020-01850-5

DO - 10.1186/s13068-020-01850-5

M3 - Journal article

AN - SCOPUS:85097582626

VL - 13

JO - Biotechnology for Biofuels

JF - Biotechnology for Biofuels

SN - 1754-6834

IS - 1

M1 - 206

ER -