Migralepsy: The Two-Faced Janus of Neurology

Giorgia Sforza; Claudia Ruscitto; Romina Moavero; Fabiana Ursitti; Michela Ada Noris Ferilli; Samuela Tarantino; Martina Balestri; Federico Vigevano; Massimiliano Valeriani; Laura Papetti

doi:10.3389/fneur.2021.711858

Migralepsy: The Two-Faced Janus of Neurology

Giorgia Sforza, Claudia Ruscitto, Romina Moavero, Fabiana Ursitti, Michela Ada Noris Ferilli, Samuela Tarantino, Martina Balestri, Federico Vigevano, Massimiliano Valeriani, Laura Papetti

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Abstract

We report three cases of pediatric patients suffering from migraine aura triggered seizures. This entity, also called migralepsy, still does not have a unique definition today. Migraine and epilepsy are both episodic neurological disorders with periods of interictal well-being; this is indicative of similar pathophysiological mechanisms, such as increased neuronal excitation and ion channel dysfunction. The purpose of this paper is to discuss the clinical and instrumental features of migralepsy through the description of three clinical cases in which the symptoms of the usual migraine aura developed into a generalized tonic-clonic or focal seizure.

Original language	English
Article number	711858
Journal	Frontiers in Neurology
Volume	12
Number of pages	5
ISSN	1664-2295
DOIs	https://doi.org/10.3389/fneur.2021.711858
Publication status	Published - 11 Oct 2021

Bibliographical note

Keywords

aura
epilepsy
migraine
migralepsy
seizure

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10.3389/fneur.2021.711858Licence: CC BY 4.0

Open Access articleFinal published version, 148 KBLicence: CC BY 4.0

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title = "Migralepsy: The Two-Faced Janus of Neurology",

abstract = "We report three cases of pediatric patients suffering from migraine aura triggered seizures. This entity, also called migralepsy, still does not have a unique definition today. Migraine and epilepsy are both episodic neurological disorders with periods of interictal well-being; this is indicative of similar pathophysiological mechanisms, such as increased neuronal excitation and ion channel dysfunction. The purpose of this paper is to discuss the clinical and instrumental features of migralepsy through the description of three clinical cases in which the symptoms of the usual migraine aura developed into a generalized tonic-clonic or focal seizure.",

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AU - Sforza, Giorgia

AU - Ruscitto, Claudia

AU - Moavero, Romina

AU - Ursitti, Fabiana

AU - Ferilli, Michela Ada Noris

AU - Tarantino, Samuela

AU - Balestri, Martina

AU - Vigevano, Federico

AU - Valeriani, Massimiliano

AU - Papetti, Laura

PY - 2021/10/11

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N2 - We report three cases of pediatric patients suffering from migraine aura triggered seizures. This entity, also called migralepsy, still does not have a unique definition today. Migraine and epilepsy are both episodic neurological disorders with periods of interictal well-being; this is indicative of similar pathophysiological mechanisms, such as increased neuronal excitation and ion channel dysfunction. The purpose of this paper is to discuss the clinical and instrumental features of migralepsy through the description of three clinical cases in which the symptoms of the usual migraine aura developed into a generalized tonic-clonic or focal seizure.

AB - We report three cases of pediatric patients suffering from migraine aura triggered seizures. This entity, also called migralepsy, still does not have a unique definition today. Migraine and epilepsy are both episodic neurological disorders with periods of interictal well-being; this is indicative of similar pathophysiological mechanisms, such as increased neuronal excitation and ion channel dysfunction. The purpose of this paper is to discuss the clinical and instrumental features of migralepsy through the description of three clinical cases in which the symptoms of the usual migraine aura developed into a generalized tonic-clonic or focal seizure.

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DO - 10.3389/fneur.2021.711858

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Migralepsy: The Two-Faced Janus of Neurology

Abstract

Bibliographical note

Keywords

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