MiR-155 is overexpressed in atopic dermatitis and modulates T cell proliferative responses by targeting CTLA-4

Enikö Sonkoly; Peter Janson; Marja-Leena Majuri; Terhi Savinko; Nanna Fyhrquist; Liv Eidsmo; Ning Xu; Florian Meisgen; Tianling Wei; Maria Bradley; Jan Stenvang; Sakari Kauppinen; Harri Alenius; Antti Lauerma; Bernhard Homey; Ola Winqvist; Mona Ståhle; Andor Pivarcsi

doi:10.1038/jid.2010.238

MiR-155 is overexpressed in atopic dermatitis and modulates T cell proliferative responses by targeting CTLA-4

Enikö Sonkoly, Peter Janson, Marja-Leena Majuri, Terhi Savinko, Nanna Fyhrquist, Liv Eidsmo, Ning Xu, Florian Meisgen, Tianling Wei, Maria Bradley, Jan Stenvang, Sakari Kauppinen, Harri Alenius, Antti Lauerma, Bernhard Homey, Ola Winqvist, Mona Ståhle, Andor Pivarcsi

Department of Chemistry and Bioscience

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

278 Citations (Scopus)

Abstract

MicroRNAs (miRNAs) are short noncoding RNAs that suppress gene expression at the posttranscriptional level. Atopic dermatitis is a common chronic inflammatory skin disease characterized by the presence of activated T cells within the skin.

Original language	English
Journal	Journal of Investigative Dermatology
Volume	130
Issue number	S2
Pages (from-to)	S3-S3
Number of pages	1
ISSN	0022-202X
DOIs	https://doi.org/10.1038/jid.2010.238
Publication status	Published - 2010

Keywords

Animals
Antigens, CD
Cell Proliferation
Dermatitis, Atopic
Dogs
Gene Expression
Humans
Lymphocyte Activation
Mice
MicroRNAs
Rats
Reverse Transcriptase Polymerase Chain Reaction
Skin
T-Lymphocytes
T-Lymphocytes, Cytotoxic

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Sonkoly, E., Janson, P., Majuri, M.-L., Savinko, T., Fyhrquist, N., Eidsmo, L., Xu, N., Meisgen, F., Wei, T., Bradley, M., Stenvang, J., Kauppinen, S., Alenius, H., Lauerma, A., Homey, B., Winqvist, O., Ståhle, M., & Pivarcsi, A. (2010). MiR-155 is overexpressed in atopic dermatitis and modulates T cell proliferative responses by targeting CTLA-4. Journal of Investigative Dermatology, 130(S2), S3-S3. https://doi.org/10.1038/jid.2010.238

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title = "MiR-155 is overexpressed in atopic dermatitis and modulates T cell proliferative responses by targeting CTLA-4",

abstract = "MicroRNAs (miRNAs) are short noncoding RNAs that suppress gene expression at the posttranscriptional level. Atopic dermatitis is a common chronic inflammatory skin disease characterized by the presence of activated T cells within the skin.",

keywords = "Animals, Antigens, CD, Cell Proliferation, Dermatitis, Atopic, Dogs, Gene Expression, Humans, Lymphocyte Activation, Mice, MicroRNAs, Rats, Reverse Transcriptase Polymerase Chain Reaction, Skin, T-Lymphocytes, T-Lymphocytes, Cytotoxic",

author = "Enik{\"o} Sonkoly and Peter Janson and Marja-Leena Majuri and Terhi Savinko and Nanna Fyhrquist and Liv Eidsmo and Ning Xu and Florian Meisgen and Tianling Wei and Maria Bradley and Jan Stenvang and Sakari Kauppinen and Harri Alenius and Antti Lauerma and Bernhard Homey and Ola Winqvist and Mona St{\aa}hle and Andor Pivarcsi",

note = "Suppl. 2",

year = "2010",

doi = "10.1038/jid.2010.238",

language = "English",

volume = "130",

pages = "S3--S3",

journal = "Journal of Investigative Dermatology",

issn = "0022-202X",

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Sonkoly, E, Janson, P, Majuri, M-L, Savinko, T, Fyhrquist, N, Eidsmo, L, Xu, N, Meisgen, F, Wei, T, Bradley, M, Stenvang, J, Kauppinen, S, Alenius, H, Lauerma, A, Homey, B, Winqvist, O, Ståhle, M & Pivarcsi, A 2010, 'MiR-155 is overexpressed in atopic dermatitis and modulates T cell proliferative responses by targeting CTLA-4', Journal of Investigative Dermatology, vol. 130, no. S2, pp. S3-S3. https://doi.org/10.1038/jid.2010.238

TY - ABST

T1 - MiR-155 is overexpressed in atopic dermatitis and modulates T cell proliferative responses by targeting CTLA-4

AU - Sonkoly, Enikö

AU - Janson, Peter

AU - Majuri, Marja-Leena

AU - Savinko, Terhi

AU - Fyhrquist, Nanna

AU - Eidsmo, Liv

AU - Xu, Ning

AU - Meisgen, Florian

AU - Wei, Tianling

AU - Bradley, Maria

AU - Stenvang, Jan

AU - Kauppinen, Sakari

AU - Alenius, Harri

AU - Lauerma, Antti

AU - Homey, Bernhard

AU - Winqvist, Ola

AU - Ståhle, Mona

AU - Pivarcsi, Andor

N1 - Suppl. 2

PY - 2010

Y1 - 2010

N2 - MicroRNAs (miRNAs) are short noncoding RNAs that suppress gene expression at the posttranscriptional level. Atopic dermatitis is a common chronic inflammatory skin disease characterized by the presence of activated T cells within the skin.

AB - MicroRNAs (miRNAs) are short noncoding RNAs that suppress gene expression at the posttranscriptional level. Atopic dermatitis is a common chronic inflammatory skin disease characterized by the presence of activated T cells within the skin.

KW - Animals

KW - Antigens, CD

KW - Cell Proliferation

KW - Dermatitis, Atopic

KW - Dogs

KW - Gene Expression

KW - Humans

KW - Lymphocyte Activation

KW - Mice

KW - MicroRNAs

KW - Rats

KW - Reverse Transcriptase Polymerase Chain Reaction

KW - Skin

KW - T-Lymphocytes

KW - T-Lymphocytes, Cytotoxic

U2 - 10.1038/jid.2010.238

DO - 10.1038/jid.2010.238

M3 - Conference abstract in journal

C2 - 20673989

SN - 0022-202X

VL - 130

SP - S3-S3

JO - Journal of Investigative Dermatology

JF - Journal of Investigative Dermatology

IS - S2

ER -

MiR-155 is overexpressed in atopic dermatitis and modulates T cell proliferative responses by targeting CTLA-4

Abstract

Keywords

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