Mitigating Teclistamab Toxicity: Prophylactic Tocilizumab and Timing of Immunoglobulin Replacement Therapy in a Nationwide Cohort

Astrid Hundebøll Torpe; Jonathan Thorsen; Gustav Mathiasen; Katrine Fladeland Iversen; Sarah Farmer; Thomas Lund; Charlotte Toftmann Hansen; Lene Kongsgaard Nielsen; Nicolai Grønne Dahlager Jørgensen; Maja Ølholm Vase; Elena Manuela Teodorescu; Morten Salomo; Christina Wennerström; Tobias S. Slørdahl; Agoston Gyula Szabo

doi:10.1002/ajh.70383

Mitigating Teclistamab Toxicity: Prophylactic Tocilizumab and Timing of Immunoglobulin Replacement Therapy in a Nationwide Cohort

Astrid Hundebøll Torpe
, Jonathan Thorsen
, Gustav Mathiasen
, Katrine Fladeland Iversen
, Sarah Farmer
, Thomas Lund
, Charlotte Toftmann Hansen
, Lene Kongsgaard Nielsen
, Nicolai Grønne Dahlager Jørgensen
, Maja Ølholm Vase
, Elena Manuela Teodorescu
, Morten Salomo
, Christina Wennerström
, Tobias S. Slørdahl
, Agoston Gyula Szabo^*

^*Corresponding author for this work

Research output: Contribution to journal › Letter › peer-review

1 Citation (Scopus)

8 Downloads (Pure)

Original language	English
Journal	American Journal of Hematology
Volume	101
Issue number	8
Pages (from-to)	2081-2085
Number of pages	5
ISSN	0361-8609
DOIs	https://doi.org/10.1002/ajh.70383
Publication status	Published - Aug 2026

Keywords

bispecific antibodies
cytokine release syndrome
IgRT
immunoglobulin
immunoglobulin replacement therapy
infections
multiple myeloma
prophylactic tocilizumab

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American J Hematol - 2026 - Torpe - Mitigating Teclistamab Toxicity Prophylactic Tocilizumab and Timing of ImmunoglobulinFinal published version, 564 KBLicence: CC BY-NC 4.0

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Torpe, A. H., Thorsen, J., Mathiasen, G., Iversen, K. F., Farmer, S., Lund, T., Hansen, C. T., Nielsen, L. K., Jørgensen, N. G. D., Vase, M. Ø., Teodorescu, E. M., Salomo, M., Wennerström, C., Slørdahl, T. S., & Szabo, A. G. (2026). Mitigating Teclistamab Toxicity: Prophylactic Tocilizumab and Timing of Immunoglobulin Replacement Therapy in a Nationwide Cohort. American Journal of Hematology, 101(8), 2081-2085. https://doi.org/10.1002/ajh.70383

@article{3dad1b6323d549acb68114ee4e007a17,

title = "Mitigating Teclistamab Toxicity: Prophylactic Tocilizumab and Timing of Immunoglobulin Replacement Therapy in a Nationwide Cohort",

keywords = "bispecific antibodies, cytokine release syndrome, IgRT, immunoglobulin, immunoglobulin replacement therapy, infections, multiple myeloma, prophylactic tocilizumab",

author = "Torpe, \{Astrid Hundeb{\o}ll\} and Jonathan Thorsen and Gustav Mathiasen and Iversen, \{Katrine Fladeland\} and Sarah Farmer and Thomas Lund and Hansen, \{Charlotte Toftmann\} and Nielsen, \{Lene Kongsgaard\} and J{\o}rgensen, \{Nicolai Gr{\o}nne Dahlager\} and Vase, \{Maja {\O}lholm\} and Teodorescu, \{Elena Manuela\} and Morten Salomo and Christina Wennerstr{\"o}m and Sl{\o}rdahl, \{Tobias S.\} and Szabo, \{Agoston Gyula\}",

year = "2026",

month = aug,

doi = "10.1002/ajh.70383",

language = "English",

volume = "101",

pages = "2081--2085",

journal = "American Journal of Hematology",

issn = "0361-8609",

publisher = "Wiley",

number = "8",

}

Torpe, AH, Thorsen, J, Mathiasen, G, Iversen, KF, Farmer, S, Lund, T, Hansen, CT, Nielsen, LK, Jørgensen, NGD, Vase, MØ, Teodorescu, EM, Salomo, M, Wennerström, C, Slørdahl, TS & Szabo, AG 2026, 'Mitigating Teclistamab Toxicity: Prophylactic Tocilizumab and Timing of Immunoglobulin Replacement Therapy in a Nationwide Cohort', American Journal of Hematology, vol. 101, no. 8, pp. 2081-2085. https://doi.org/10.1002/ajh.70383

TY - JOUR

T1 - Mitigating Teclistamab Toxicity

T2 - Prophylactic Tocilizumab and Timing of Immunoglobulin Replacement Therapy in a Nationwide Cohort

AU - Torpe, Astrid Hundebøll

AU - Thorsen, Jonathan

AU - Mathiasen, Gustav

AU - Iversen, Katrine Fladeland

AU - Farmer, Sarah

AU - Lund, Thomas

AU - Hansen, Charlotte Toftmann

AU - Nielsen, Lene Kongsgaard

AU - Jørgensen, Nicolai Grønne Dahlager

AU - Vase, Maja Ølholm

AU - Teodorescu, Elena Manuela

AU - Salomo, Morten

AU - Wennerström, Christina

AU - Slørdahl, Tobias S.

AU - Szabo, Agoston Gyula

PY - 2026/8

Y1 - 2026/8

KW - bispecific antibodies

KW - cytokine release syndrome

KW - IgRT

KW - immunoglobulin

KW - immunoglobulin replacement therapy

KW - infections

KW - multiple myeloma

KW - prophylactic tocilizumab

UR - https://www.scopus.com/pages/publications/105040079683

U2 - 10.1002/ajh.70383

DO - 10.1002/ajh.70383

M3 - Letter

C2 - 42192604

AN - SCOPUS:105040079683

SN - 0361-8609

VL - 101

SP - 2081

EP - 2085

JO - American Journal of Hematology

JF - American Journal of Hematology

IS - 8

ER -

Mitigating Teclistamab Toxicity: Prophylactic Tocilizumab and Timing of Immunoglobulin Replacement Therapy in a Nationwide Cohort

Keywords

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