Modulation of cortical activity by selective steady-state somatosensory stimulation

Research output: Contribution to book/anthology/report/conference proceedingArticle in proceedingResearchpeer-review

1 Citation (Scopus)

Abstract

Phantom limb pain (PLP) represents a major debilitating condition for amputees. No effective therapy has been reported. Non-painful surface electrical stimulation may induce temporary significant alleviation of PLP. Preliminary results of a study attempting to design a methodology for delivery and evaluation of possible quantifiable effects at the cortical level of steady-state surface stimulation are presented for two healthy subjects. Somatosensory evoked potentials (SEP) were evaluated before and after delivery of a steady-state stimulus applied at wrist along the median nerve. Characterization of evoked sensation induced in hand by the steady-state stimuli was performed. The sensory input artificially generated by the steady-state stimuli influenced cortical activation reflected in changes in N1 and P2 components of SEP. N1 suppression and changes in P2 amplitude after steady state stimulation between 1 to 7 minutes were observed. Analysis of changes in SEP components in a larger population may contribute to defining markers of temporary cortical plastic changes driven by steady-state stimuli possibly assessing the efficacy of these stimuli when attempting to reverse cortical plastic changes following amputation and relief of PLP upon specific delivery through surface electrical stimulation in the periphery.
Original languageEnglish
Title of host publication 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
Number of pages4
PublisherIEEE
Publication date2019
Pages421-424
Article number8856443
ISBN (Print)978-1-5386-1312-2
ISBN (Electronic)978-1-5386-1311-5
DOIs
Publication statusPublished - 2019
Event41st International Engineering in Medicine and Biology Conference (EMB) 2019 - Berlin, Germany
Duration: 23 Jul 201927 Jul 2019
Conference number: 41
https://embc.embs.org/2019/

Conference

Conference41st International Engineering in Medicine and Biology Conference (EMB) 2019
Number41
CountryGermany
CityBerlin
Period23/07/201927/07/2019
Internet address
SeriesConference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference
ISSN1557-170X

Keywords

  • Phantom Limb Pain
  • Sensory Feedback
  • Cortical Reorganization

Fingerprint Dive into the research topics of 'Modulation of cortical activity by selective steady-state somatosensory stimulation'. Together they form a unique fingerprint.

Cite this