Modulation of the Viscoelastic Response of Hydrogels with Supramolecular Bonds

Aleksey D. Drozdov*

*Corresponding author for this work

Research output: Contribution to book/anthology/report/conference proceedingBook chapterResearchpeer-review

Abstract

The viscoelastic response of supramolecular gels (whose polymer networks are formed by chains bridged by supramolecular and dynamic covalent bonds) can be tuned in a rather wide interval by changes in chemistry of the surrounding solutions. This property plays an important role in biomedical applications of these materials for stem cell therapy, regenerative medicine, and neuromodulation. A simple model is developed in finite viscoelasticity of supramolecular gels. An advantage of the constitutive equations is that they involve only three material parameters. The ability of the model to describe experimental data is confirmed by fitting observations on hyaluronic acid gels, poly(ethylene glycol) gels, and poly(acrylamide) gels with reversible bonds in uniaxial tensile and compressive tests with large strains and in small-amplitude shear oscillatory tests.

Original languageEnglish
Title of host publicationAdvances in Mechanics of Time-Dependent Materials
EditorsHolm Altenbach, Julius Kaplunov, Hongbing Lu, Masayuki Nakada
Number of pages18
PublisherSpringer
Publication date2023
Pages39-56
Chapter3
ISBN (Print)978-3-031-22400-3
ISBN (Electronic)978-3-031-22401-0
DOIs
Publication statusPublished - 2023
SeriesAdvanced Structured Materials
Volume188
ISSN1869-8433

Bibliographical note

Publisher Copyright:
© 2023, The Author(s), under exclusive license to Springer Nature Switzerland AG.

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