Abstract
The effect of positive expiratory pressure (PEP) and inhaled terbutaline was evaluated in ten patients with chronic obstructive pulmonary disease in a randomized cross-over study with three 2 weeks periods. In one period 5 mg terbutaline was inhaled 3 times daily from a nebulizer combined with PEP. In a second period 5 mg terbutaline was inhaled similarly but without PEP and in a third period placebo inhalations were combined with PEP. Symptom score and peak expiratory flow (PEF) measured before and after each inhalation was noted in a diary. The treatment with nebulized terbutaline combined with PEP gave the best relief in symptoms. All treatments increased PEF significantly. PEP alone gave the least increase in PEF (25 1/min), and there was no difference between the increase in PEF after terbutaline inhaled with PEP (28 1/min) compared to terbutaline alone (29 1/min).
Original language | English |
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Journal | Broncho-pneumologie |
Volume | 45 |
Issue number | 3 |
Pages (from-to) | 105-109 |
Number of pages | 5 |
ISSN | 0934-8387 |
Publication status | Published - 1991 |
Externally published | Yes |
Keywords
- Adult
- Aged
- Female
- Humans
- Lung Diseases, Obstructive
- Male
- Middle Aged
- Nebulizers and Vaporizers
- Peak Expiratory Flow Rate
- Positive-Pressure Respiration
- Terbutaline